ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 7.4.1

Subclass Accession number: 9162
Subclass: 7.4.1

Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 6

Average sequence ID (%) : 42.1 +/- 24.5
Average RMSD (Å) : 0.417 +/- 0.117

Consensus geometry

d (Å): 17

delta (°): 90-135

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	XQRXhMVQTpX
(φψ)-conformation:	aabplplabaa

Pattern:	[IMV]	[fkqy]	[GKQ]	[ftv]	[ILV]	[kqst]	x	[ILMV]	[R]	[AKST]	[QY]	[R]	[cnps]	[agy]	[LM]	[IV]	[Q]	[T]	[DEP]	[ad]	[Q]	[LY]	x	[fl]	[ci]	[HY]	x	[A]	[AILV]	[ail]	[EHQ]	[afgy]
Conservation:	0.273	-1.154	-0.631	-1.023	0.295	-1.053	-1.191	0.035	1.548	-0.577	0.292	1.548	-1.228	-1.020	0.838	0.759	1.548	1.548	0.015	-0.909	1.548	0.773	-0.872	-0.379	-0.729	1.646	-0.955	0.982	-0.332	-0.951	0.248	-0.890

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1fpr_A_486	1fpr	A	486	517	IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQF	HHHHHHHHHTTSTTSS-SSHHHHHHHHHHHHH	aaaaaaaaaaabxgpvabaaaaaaaaaaaaaa
1l8k_A_244	1l8k	A	244	275	IKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEG	HHHHHHHHTTTBTT-S-SHHHHHHHHHHHHHH	aaaaaaaaaaabxvpMabaaaaaaaaaaaaaa
1lar_A_1550	1lar	A	1550	1581	IYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA	HHHHHHHHHTTSTTSS-SHHHHHHHHHHHHHH	aaaaaaaaaaabplpvabaaaaaaaaaaaaaa
1lar_A_1841	1lar	A	1841	1872	MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY	HHHHHHHHTTTSTTSS-SHHHHHHHHHHHHHH	aaaaaaaaaaabxvpvabaaaaaaaaaaaaaa
1yfo_A_461	1yfo	A	461	492	VYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH	HHHHHHHHTTTSTTSS-SHHHHHHHHHHHHHH	aaaaaaaaaaabxlxvabaaaaaaaaaaaaaa
2shp_A_490	2shp	A	490	521	VPKTIQMVRSQRSGMVQTEAQYRSIYMAVQHY	HHHHHHHHHTTSTTSS--HHHHHHHHHHHHHH	aaaaaaaaaaabxvpMabaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1fpr_A_486	1fpr	A	PTRO-PHOSPHOTYROSINE	Q - 502
1fpr_A_486	1fpr	A	PTRO-PHOSPHOTYROSINE	Q - 506
2shp_A_490	2shp	A	CATDODECANE-TRIMETHYLAMINE	Q - 510
2shp_A_490	2shp	A	CATDODECANE-TRIMETHYLAMINE	S - 513
2shp_A_490	2shp	A	CATDODECANE-TRIMETHYLAMINE	I - 514
2shp_A_490	2shp	A	CATDODECANE-TRIMETHYLAMINE	M - 516
2shp_A_490	2shp	A	CATDODECANE-TRIMETHYLAMINE	A - 517

Clusters included in this Subclass