PDB: 1ad5 Compound: haematopoetic cell kinase hck Classification: TYROSINE-PROTEIN KINASE Entry date in PDB: 1997-05-15 Resolution [Å]: 2.60 R-Factor: 0.239

CHAIN: A SWISS-PROT/TREMBL: P08631    KEYWORD: 3D-structure    Alternative initiation    ATP-binding    Lipoprotein    Myristate    Palmitate    Phosphorylation    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Hemapoetic cell kinase Hck    Human (Homo sapiens) SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    Hemopoetic cell kinase Hck    Human (Homo sapiens) SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Haemopoetic cell kinase Hck    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation    CHAIN: B SWISS-PROT/TREMBL: P08631    KEYWORD: 3D-structure    Alternative initiation    ATP-binding    Lipoprotein    Myristate    Palmitate    Phosphorylation    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Hemapoetic cell kinase Hck    Human (Homo sapiens) SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    Hemopoetic cell kinase Hck    Human (Homo sapiens) SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Haemopoetic cell kinase Hck    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation

Image Source: PDB

Loops in ArchDB-KI clusters

1ad5_A_129 - AR => SUBCLASS : 3.2.1
1ad5_A_279 - HA => SUBCLASS : 3.3.1
1ad5_A_118 - HA => SUBCLASS : 4.1.1
1ad5_A_392 - HA => SUBCLASS : 4.1.1
1ad5_A_172 - HA => SUBCLASS : 7.1.1
1ad5_A_85 - HA => SUBCLASS : 18.1.1
1ad5_A_304 - HE => SUBCLASS : 8.1.1
1ad5_A_431 - HH => SUBCLASS : 4.2.1
1ad5_A_489 - HH => SUBCLASS : 9.1.4
1ad5_A_469 - HH => SUBCLASS : 11.1.1

Loops not clustered in ArchDB-KI

1ad5_A_195 - AR
1ad5_A_334 - AR
1ad5_A_137 - AR
1ad5_A_149 - EH
1ad5_A_400 - EH
1ad5_A_290 - EH
1ad5_A_212 - EH
1ad5_A_344 - EH
1ad5_A_184 - HA
1ad5_A_107 - HA
1ad5_A_267 - HA
1ad5_A_205 - HA
1ad5_A_325 - HA
1ad5_A_223 - HE
1ad5_A_360 - HE
1ad5_A_155 - HE
1ad5_A_346 - HH
1ad5_A_353 - HH
1ad5_A_441 - HH

1cwd L - percentage of sequence identity: 72
1efn A - percentage of sequence identity: 63
1fmk - - percentage of sequence identity: 61
1lck A - percentage of sequence identity: 64
1lkk A - percentage of sequence identity: 70
1qcf A - percentage of sequence identity: 97
1qpc A - percentage of sequence identity: 73
1shf A - percentage of sequence identity: 61