PDB: 1aky Compound: adenylate kinase Classification: TRANSFERASE (PHOSPHOTRANSFERASE) Entry date in PDB: 1995-11-14 Resolution [Å]: 1.63 R-Factor: 0.194

CHAIN: - SWISS-PROT/TREMBL: P07170    KEYWORD: 3D-structure    Acetylation    ATP-binding    Kinase    Transferase    EC: 2.7.4.3 SCOP: c.37.1.1 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    Nucleotide and nucleoside kinases    Adenylate kinase    Baker's yeast (Saccharomyces cerevisiae) SCOP: c.37.1.1 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    Nucleotide and nucleoside kinases    Adenylate kinase    Baker's yeast (Saccharomyces cerevisiae) SCOP: g.41.2.1 Small proteins    Rubredoxin-like    Microbial and mitochondrial ADK, insert "zinc finger" domain    Microbial and mitochondrial ADK, insert "zinc finger" domain    Microbial and mitochondrial ADK, insert "zinc finger" domain    Baker's yeast (Saccharomyces cerevisiae) GO:  adenylate kinase activity    ATP binding    nucleotide kinase activity    phosphotransferase activity, phosphate group as acceptor    nucleobase, nucleoside, nucleotide and nucleic acid metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1aky_*_17 - HE => SUBCLASS : 1.1.1
1aky_*_17 - HE => SUBCLASS : 1.1.4
1aky_*_186 - HE => SUBCLASS : 2.4.1
1aky_*_65 - HE => SUBCLASS : 7.10.1
1aky_*_132 - HA => SUBCLASS : 4.1.2
1aky_*_132 - HA => SUBCLASS : 6.1.1
1aky_*_31 - EH => SUBCLASS : 0.1.2
1aky_*_114 - EH => SUBCLASS : 1.1.5
1aky_*_197 - EH => SUBCLASS : 5.1.2
1aky_*_6 - EH => SUBCLASS : 5.7.1
1aky_*_35 - HH => SUBCLASS : 2.2.3
1aky_*_48 - HH => SUBCLASS : 5.3.1

Loops in ArchDB95 clusters

1aky_*_31 - EH => SUBCLASS : 0.1.1
1aky_*_114 - EH => SUBCLASS : 1.1.3
1aky_*_197 - EH => SUBCLASS : 4.2.3
1aky_*_6 - EH => SUBCLASS : 5.5.1
1aky_*_35 - HH => SUBCLASS : 2.2.4
1aky_*_48 - HH => SUBCLASS : 5.4.1
1aky_*_17 - HE => SUBCLASS : 1.1.1
1aky_*_17 - HE => SUBCLASS : 1.2.2
1aky_*_17 - HE => SUBCLASS : 1.2.3
1aky_*_186 - HE => SUBCLASS : 2.4.1
1aky_*_65 - HE => SUBCLASS : 7.9.1
1aky_*_132 - HA => SUBCLASS : 4.1.1

Loops in ArchDB-EC clusters

1aky_*_48 - HH => SUBCLASS : 5.3.2

Loops in ArchDB-KI clusters

1aky_*_31 - EH => SUBCLASS : 0.1.1
1aky_*_114 - EH => SUBCLASS : 1.1.1
1aky_*_197 - EH => SUBCLASS : 4.1.1
1aky_*_86 - EH => SUBCLASS : 5.1.1
1aky_*_6 - EH => SUBCLASS : 6.1.1
1aky_*_132 - HA => SUBCLASS : 4.1.1
1aky_*_122 - HE => SUBCLASS : 0.1.1
1aky_*_17 - HE => SUBCLASS : 2.1.1
1aky_*_186 - HE => SUBCLASS : 2.4.1
1aky_*_95 - HE => SUBCLASS : 5.1.1
1aky_*_65 - HE => SUBCLASS : 7.1.1
1aky_*_35 - HH => SUBCLASS : 2.2.1
1aky_*_48 - HH => SUBCLASS : 5.1.1

Loops not clustered in ArchDB

1aky_*_86 - EH
1aky_*_141 - EH
1aky_*_132 - HA
1aky_*_95 - HE
1aky_*_122 - HE
1aky_*_170 - HH

Loops not clustered in ArchDB-KI

1aky_*_141 - EH
1aky_*_170 - HH

1dvr A - percentage of sequence identity: 99
1dvr B - percentage of sequence identity: 99
2aky - - percentage of sequence identity: 100
3aky - - percentage of sequence identity: 99