PDB: 1apy Compound: aspartylglucosaminidase Classification: HYDROLASE Entry date in PDB: 1996-12-23 Resolution [Å]: 2.00 R-Factor: 0.169

CHAIN: A SWISS-PROT/TREMBL: P20933    KEYWORD: 3D-structure    Disease mutation    Glycoprotein    Hydrolase    Lysosome    Signal    EC: 3.5.1.26 SCOP: d.153.1.5 Alpha and beta proteins (a+b)    Ntn hydrolase-like    N-terminal nucleophile aminohydrolases (Ntn hydrolases)    (Glycosyl)asparaginase    Glycosylasparaginase (aspartylglucosaminidase, AGA)    Human (Homo sapiens) GO:  asparaginase activity    glycoprotein catabolism    CHAIN: B SWISS-PROT/TREMBL: P20933    KEYWORD: 3D-structure    Disease mutation    Glycoprotein    Hydrolase    Lysosome    Signal    EC: 3.5.1.26 SCOP: d.153.1.5 Alpha and beta proteins (a+b)    Ntn hydrolase-like    N-terminal nucleophile aminohydrolases (Ntn hydrolases)    (Glycosyl)asparaginase    Glycosylasparaginase (aspartylglucosaminidase, AGA)    Human (Homo sapiens) GO:  asparaginase activity    glycoprotein catabolism    CHAIN: C SWISS-PROT/TREMBL: P20933    KEYWORD: 3D-structure    Disease mutation    Glycoprotein    Hydrolase    Lysosome    Signal    EC: 3.5.1.26 SCOP: d.153.1.5 Alpha and beta proteins (a+b)    Ntn hydrolase-like    N-terminal nucleophile aminohydrolases (Ntn hydrolases)    (Glycosyl)asparaginase    Glycosylasparaginase (aspartylglucosaminidase, AGA)    Human (Homo sapiens) GO:  asparaginase activity    glycoprotein catabolism    CHAIN: D SWISS-PROT/TREMBL: P20933    KEYWORD: 3D-structure    Disease mutation    Glycoprotein    Hydrolase    Lysosome    Signal    EC: 3.5.1.26 SCOP: d.153.1.5 Alpha and beta proteins (a+b)    Ntn hydrolase-like    N-terminal nucleophile aminohydrolases (Ntn hydrolases)    (Glycosyl)asparaginase    Glycosylasparaginase (aspartylglucosaminidase, AGA)    Human (Homo sapiens) GO:  asparaginase activity    glycoprotein catabolism

Image Source: PDB

Loops in ArchDB40 clusters

1apy_B_184 - HA => SUBCLASS : 3.1.1
1apy_B_222 - HA => SUBCLASS : 3.2.2
1apy_A_64 - HA => SUBCLASS : 4.1.1
1apy_B_279 - HA => SUBCLASS : 4.2.1
1apy_A_64 - HA => SUBCLASS : 6.1.1
1apy_B_302 - HA => SUBCLASS : 7.2.1
1apy_B_229 - EH => SUBCLASS : 1.1.32
1apy_A_76 - EH => SUBCLASS : 2.9.1
1apy_A_14 - HH => SUBCLASS : 3.3.1
1apy_B_245 - HH => SUBCLASS : 3.3.1

Loops in ArchDB95 clusters

1apy_B_229 - EH => SUBCLASS : 1.1.30
1apy_B_229 - EH => SUBCLASS : 2.5.1
1apy_A_76 - EH => SUBCLASS : 3.19.2
1apy_A_14 - HH => SUBCLASS : 3.2.1
1apy_B_245 - HH => SUBCLASS : 3.2.1
1apy_A_88 - HE => SUBCLASS : 4.44.1
1apy_B_184 - HA => SUBCLASS : 3.1.1
1apy_B_279 - HA => SUBCLASS : 3.1.2
1apy_B_222 - HA => SUBCLASS : 3.3.3
1apy_A_64 - HA => SUBCLASS : 4.1.1
1apy_B_302 - HA => SUBCLASS : 6.6.1

Loops in ArchDB-EC clusters

1apy_A_14 - HH => SUBCLASS : 3.2.1

Loops not clustered in ArchDB

1apy_B_290 - AR
1apy_B_195 - AR
1apy_B_195 - AR
1apy_B_290 - AR
1apy_A_103 - EH
1apy_B_279 - HA
1apy_B_222 - HA
1apy_B_184 - HA
1apy_A_64 - HA
1apy_B_302 - HA
1apy_B_259 - HE
1apy_A_30 - HE
1apy_B_237 - HH
1apy_A_106 - HH

1apy B - percentage of sequence identity: 100
1apy D - percentage of sequence identity: 100
1apz B - percentage of sequence identity: 100
1apz D - percentage of sequence identity: 100