PDB: 1b6a Compound: methionine aminopeptidase Classification: ANGIOGENESIS INHIBITOR Entry date in PDB: 2000-01-13 Resolution [Å]: 1.60 R-Factor: 0.187

CHAIN: - SWISS-PROT/TREMBL: P50579    KEYWORD: 3D-structure    Aminopeptidase    Cobalt    Hydrolase    EC: 3.4.11.18 SCOP: a.4.5.25 All alpha proteins    DNA/RNA-binding 3-helical bundle    "Winged helix" DNA-binding domain    Methionine aminopeptidase, insert domain    Methionine aminopeptidase, insert domain    Human (Homo sapiens) SCOP: d.127.1.1 Alpha and beta proteins (a+b)    Creatinase/aminopeptidase    Creatinase/aminopeptidase    Creatinase/aminopeptidase    Methionine aminopeptidase    Human (Homo sapiens) SCOP: d.127.1.1 Alpha and beta proteins (a+b)    Creatinase/aminopeptidase    Creatinase/aminopeptidase    Creatinase/aminopeptidase    Methionine aminopeptidase    Human (Homo sapiens) GO:  metalloexopeptidase activity    methionyl aminopeptidase activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1b6a_*_297 - HE => SUBCLASS : 1.2.1
1b6a_*_429 - HE => SUBCLASS : 2.4.1
1b6a_*_248 - HA => SUBCLASS : 2.1.1
1b6a_*_248 - HA => SUBCLASS : 2.1.3
1b6a_*_248 - HA => SUBCLASS : 2.1.4
1b6a_*_455 - HA => SUBCLASS : 3.8.2
1b6a_*_323 - AR => SUBCLASS : 4.3.8
1b6a_*_447 - AR => SUBCLASS : 4.4.5
1b6a_*_447 - AR => SUBCLASS : 4.41.1
1b6a_*_163 - HH => SUBCLASS : 6.1.1

Loops in ArchDB95 clusters

1b6a_*_447 - AR => SUBCLASS : 4.5.1
1b6a_*_323 - AR => SUBCLASS : 4.6.7
1b6a_*_163 - HH => SUBCLASS : 6.2.1
1b6a_*_297 - HE => SUBCLASS : 1.3.6
1b6a_*_429 - HE => SUBCLASS : 2.4.1
1b6a_*_397 - HE => SUBCLASS : 3.24.1
1b6a_*_248 - HA => SUBCLASS : 2.1.1
1b6a_*_248 - HA => SUBCLASS : 2.1.4
1b6a_*_455 - HA => SUBCLASS : 3.12.4

Loops in ArchDB-EC clusters

1b6a_*_163 - HH => SUBCLASS : 6.2.3

Loops not clustered in ArchDB

1b6a_*_360 - AR
1b6a_*_318 - AR
1b6a_*_375 - AR
1b6a_*_228 - AR
1b6a_*_441 - AR
1b6a_*_228 - AR
1b6a_*_318 - AR
1b6a_*_323 - AR
1b6a_*_343 - AR
1b6a_*_360 - AR
1b6a_*_375 - AR
1b6a_*_441 - AR
1b6a_*_447 - AR
1b6a_*_343 - AR
1b6a_*_133 - EH
1b6a_*_259 - EH
1b6a_*_382 - EH
1b6a_*_415 - EH
1b6a_*_329 - HA
1b6a_*_329 - HA
1b6a_*_455 - HA
1b6a_*_312 - HA
1b6a_*_248 - HA
1b6a_*_215 - HA
1b6a_*_215 - HA
1b6a_*_312 - HA
1b6a_*_193 - HE
1b6a_*_120 - HE
1b6a_*_274 - HH
1b6a_*_417 - HH
1b6a_*_154 - HH

1b59 A - percentage of sequence identity: 100
1bn5 - - percentage of sequence identity: 99
1boa - - percentage of sequence identity: 99
1kq0 A - percentage of sequence identity: 99
1kq9 A - percentage of sequence identity: 99
1qzy A - percentage of sequence identity: 99
1r58 A - percentage of sequence identity: 99
1r5g A - percentage of sequence identity: 99
1r5h A - percentage of sequence identity: 99
1yw7 A - percentage of sequence identity: 99
1yw8 A - percentage of sequence identity: 99
1yw9 A - percentage of sequence identity: 99
2adu A - percentage of sequence identity: 99