PDB: 1b6c Compound: fk506-binding protein Classification: COMPLEX (ISOMERASE/PROTEIN KINASE) Entry date in PDB: 1999-06-15 Resolution [Å]: 2.60 R-Factor: 0.249

CHAIN: B SWISS-PROT/TREMBL: P36897    KEYWORD: 3D-structure    ATP-binding    Glycoprotein    Receptor    Serine/threonine-protein kinase    Signal    Transferase    Transmembrane    EC: 2.7.1.37 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Type I TGF-beta receptor R4    Human (Homo sapiens) GO:  membrane    ATP binding    protein kinase activity    protein serine/threonine kinase activity    receptor signaling protein serine/threonine kinase activity    transforming growth factor beta receptor activity    transmembrane receptor protein serine/threonine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein serine/threonine kinase signaling pathway    CHAIN: D SWISS-PROT/TREMBL: P36897    KEYWORD: 3D-structure    ATP-binding    Glycoprotein    Receptor    Serine/threonine-protein kinase    Signal    Transferase    Transmembrane    EC: 2.7.1.37 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Type I TGF-beta receptor R4    Human (Homo sapiens) GO:  membrane    ATP binding    protein kinase activity    protein serine/threonine kinase activity    receptor signaling protein serine/threonine kinase activity    transforming growth factor beta receptor activity    transmembrane receptor protein serine/threonine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein serine/threonine kinase signaling pathway    CHAIN: F SWISS-PROT/TREMBL: P36897    KEYWORD: 3D-structure    ATP-binding    Glycoprotein    Receptor    Serine/threonine-protein kinase    Signal    Transferase    Transmembrane    EC: 2.7.1.37 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Type I TGF-beta receptor R4    Human (Homo sapiens) GO:  membrane    ATP binding    protein kinase activity    protein serine/threonine kinase activity    receptor signaling protein serine/threonine kinase activity    transforming growth factor beta receptor activity    transmembrane receptor protein serine/threonine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein serine/threonine kinase signaling pathway    CHAIN: H SWISS-PROT/TREMBL: P36897    KEYWORD: 3D-structure    ATP-binding    Glycoprotein    Receptor    Serine/threonine-protein kinase    Signal    Transferase    Transmembrane    EC: 2.7.1.37 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Type I TGF-beta receptor R4    Human (Homo sapiens) GO:  membrane    ATP binding    protein kinase activity    protein serine/threonine kinase activity    receptor signaling protein serine/threonine kinase activity    transforming growth factor beta receptor activity    transmembrane receptor protein serine/threonine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein serine/threonine kinase signaling pathway

Image Source: PDB

Loops in ArchDB-EC clusters

1b6c_B_462 - HH => SUBCLASS : 9.1.1

Loops in ArchDB-KI clusters

1b6c_B_347 - AR => SUBCLASS : 5.1.1
1b6c_B_328 - AR => SUBCLASS : 8.1.1
1b6c_B_276 - EH => SUBCLASS : 7.2.1
1b6c_B_356 - HA => SUBCLASS : 4.1.1
1b6c_B_339 - HA => SUBCLASS : 4.1.1
1b6c_B_462 - HH => SUBCLASS : 9.1.1

Loops not clustered in ArchDB

1b6c_B_347 - AR
1b6c_B_328 - AR
1b6c_B_227 - EH
1b6c_B_276 - EH
1b6c_B_364 - EH
1b6c_B_339 - HA
1b6c_B_262 - HA
1b6c_B_217 - HA
1b6c_B_206 - HA
1b6c_B_356 - HA
1b6c_B_299 - HE
1b6c_B_239 - HE
1b6c_B_195 - HE
1b6c_B_438 - HH
1b6c_B_381 - HH
1b6c_B_288 - HH
1b6c_B_177 - HH
1b6c_B_393 - HH

Loops not clustered in ArchDB-KI

1b6c_B_227 - EH
1b6c_B_364 - EH
1b6c_B_206 - HA
1b6c_B_217 - HA
1b6c_B_262 - HA
1b6c_B_239 - HE
1b6c_B_195 - HE
1b6c_B_299 - HE
1b6c_B_381 - HH
1b6c_B_177 - HH
1b6c_B_288 - HH
1b6c_B_393 - HH
1b6c_B_438 - HH

1b6c B - percentage of sequence identity: 100
1b6c D - percentage of sequence identity: 100
1b6c F - percentage of sequence identity: 100
1b6c H - percentage of sequence identity: 100
1bkf - - percentage of sequence identity: 98
1c9h A - percentage of sequence identity: 83
1fkl - - percentage of sequence identity: 97
1ias A - percentage of sequence identity: 100
1ias B - percentage of sequence identity: 100
1ias C - percentage of sequence identity: 100
1ias D - percentage of sequence identity: 100
1ias E - percentage of sequence identity: 100
1py5 A - percentage of sequence identity: 100
1rw8 A - percentage of sequence identity: 100
1vjy A - percentage of sequence identity: 100