PDB: 1bbz Compound: abl tyrosine kinase Classification: COMPLEX (TRANSFERASE/PEPTIDE) Entry date in PDB: 1998-11-25 Resolution [Å]: 1.65 R-Factor: 0.205

CHAIN: A SWISS-PROT/TREMBL: P00519    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Abl tyrosine kinase, SH3 domain    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation    CHAIN: C SWISS-PROT/TREMBL: P00519    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Abl tyrosine kinase, SH3 domain    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation    CHAIN: E SWISS-PROT/TREMBL: P00519    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Abl tyrosine kinase, SH3 domain    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation    CHAIN: G SWISS-PROT/TREMBL: P00519    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Abl tyrosine kinase, SH3 domain    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation

Image Source: PDB

Loops in ArchDB40 clusters

1bbz_A_36 - HA => SUBCLASS : 2.2.2
1bbz_A_24 - HA => SUBCLASS : 5.2.1
1bbz_A_44 - AR => SUBCLASS : 3.4.1

Loops in ArchDB95 clusters

1bbz_A_44 - AR => SUBCLASS : 3.2.2
1bbz_A_44 - AR => SUBCLASS : 3.2.4
1bbz_A_36 - HA => SUBCLASS : 2.2.2
1bbz_A_24 - HA => SUBCLASS : 5.2.1

Loops in ArchDB-EC clusters

1bbz_A_24 - HA => SUBCLASS : 5.2.2

Loops not clustered in ArchDB

1bbz_A_44 - AR
1bbz_A_2 - HA
1bbz_A_2 - HA
1bbz_A_24 - HA
1bbz_A_36 - HA

1abo A - percentage of sequence identity: 100
1abo B - percentage of sequence identity: 100
1abq - - percentage of sequence identity: 100
1awo - - percentage of sequence identity: 96
1bbz A - percentage of sequence identity: 100
1bbz C - percentage of sequence identity: 100
1bbz E - percentage of sequence identity: 98
1bbz G - percentage of sequence identity: 100
1ju5 C - percentage of sequence identity: 100
1opk A - percentage of sequence identity: 100
1opl A - percentage of sequence identity: 100
1opl B - percentage of sequence identity: 100
2abl - - percentage of sequence identity: 100