PDB: 1bia Compound: Bira bifunctional protein (acts as biotin operon r Classification: TRANSCRIPTION REGULATION Entry date in PDB: 1993-10-31 Resolution [Å]: 2.30 R-Factor: 0.190

CHAIN: - SWISS-PROT/TREMBL: P06709    KEYWORD: 3D-structure    Biotin    Complete proteome    DNA-binding    Ligase    Repressor    Transcription regulation    EC: 6.3.4.15 SCOP: a.4.5.1 All alpha proteins    DNA/RNA-binding 3-helical bundle    "Winged helix" DNA-binding domain    Biotin repressor-like    Biotin repressor, N-terminal domain    Escherichia coli SCOP: b.34.1.1 All beta proteins    SH3-like barrel    C-terminal domain of transcriptional repressors    Biotin repressor (BirA)    Biotin repressor/biotin holoenzyme synthetase, C-terminal domain    Escherichia coli SCOP: d.104.1.2 Alpha and beta proteins (a+b)    Class II aaRS and biotin synthetases    Class II aaRS and biotin synthetases    Biotin holoenzyme synthetase    Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain    Escherichia coli GO:  biotin-[acetyl-CoA-carboxylase] ligase activity    catalytic activity    transcriptional repressor activity    protein modification    regulation of transcription, DNA-dependent

Image Source: PDB

Loops in ArchDB40 clusters

1bia_*_33 - HE => SUBCLASS : 3.2.1
1bia_*_147 - HE => SUBCLASS : 5.34.1
1bia_*_176 - HA => SUBCLASS : 2.4.6
1bia_*_170 - HA => SUBCLASS : 3.28.1
1bia_*_283 - HA => SUBCLASS : 5.3.9
1bia_*_305 - AR => SUBCLASS : 3.21.1
1bia_*_305 - AR => SUBCLASS : 4.35.1
1bia_*_22 - HH => SUBCLASS : 3.1.1
1bia_*_5 - HH => SUBCLASS : 5.24.1

Loops in ArchDB95 clusters

1bia_*_305 - AR => SUBCLASS : 3.21.1
1bia_*_22 - HH => SUBCLASS : 3.1.1
1bia_*_5 - HH => SUBCLASS : 5.18.1
1bia_*_5 - HH => SUBCLASS : 5.18.2
1bia_*_33 - HE => SUBCLASS : 3.5.1
1bia_*_147 - HE => SUBCLASS : 5.23.3
1bia_*_176 - HA => SUBCLASS : 2.5.3
1bia_*_170 - HA => SUBCLASS : 3.25.1
1bia_*_283 - HA => SUBCLASS : 5.4.10

Loops in ArchDB-EC clusters

1bia_*_5 - HH => SUBCLASS : 5.3.4

Loops not clustered in ArchDB

1bia_*_305 - AR
1bia_*_57 - EH
1bia_*_199 - EH
1bia_*_130 - EH
1bia_*_81 - EH
1bia_*_106 - HA
1bia_*_170 - HA
1bia_*_176 - HA
1bia_*_182 - HA
1bia_*_275 - HA
1bia_*_283 - HA
1bia_*_298 - HA
1bia_*_51 - HA
1bia_*_298 - HA
1bia_*_182 - HA
1bia_*_106 - HA
1bia_*_51 - HA
1bia_*_275 - HA
1bia_*_262 - HE
1bia_*_90 - HE
1bia_*_69 - HE
1bia_*_235 - HH

1bib - - percentage of sequence identity: 100
1hxd A - percentage of sequence identity: 100
1hxd B - percentage of sequence identity: 100
2ewn A - percentage of sequence identity: 100
2ewn B - percentage of sequence identity: 100