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Information on 1cs8
PDB: 1cs8
Compound: human procathepsin l
Classification: HYDROLASE
Entry date in PDB: 1999-08-23
Resolution [Å]: 1.80
R-Factor: 0.207


CHAIN: A
SWISS-PROT/TREMBL: P07711
   KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Lysosome    Signal    Thiol protease    Zymogen   
EC: 3.4.22.15
SCOP: d.3.1.1 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Papain-like    (Pro)cathepsin L    Human (Homo sapiens)
GO:  cysteine-type endopeptidase activity    cysteine-type peptidase activity    proteolysis and peptidolysis   
1cs8 Image
Image Source: PDB

Stored Loops of 1cs8

Loops in ArchDB40 clusters

1cs8_A_119 - HE => SUBCLASS : 2.9.3
1cs8_A_27 - HE => SUBCLASS : 4.2.3
1cs8_A_180 - HA => SUBCLASS : 10.1.1
1cs8_A_132 - EH => SUBCLASS : 4.9.1
1cs8_A_112 - EH => SUBCLASS : 4.17.2

Loops in ArchDB95 clusters

1cs8_A_132 - EH => SUBCLASS : 4.1.4
1cs8_A_112 - EH => SUBCLASS : 4.15.3
1cs8_A_119 - HE => SUBCLASS : 2.8.1
1cs8_A_119 - HE => SUBCLASS : 2.8.2
1cs8_A_27 - HE => SUBCLASS : 4.2.5
1cs8_A_180 - HA => SUBCLASS : 11.1.1

Loops in ArchDB-EC clusters

1cs8_A_27 - HE => SUBCLASS : 4.2.4

Loops not clustered in ArchDB

1cs8_A_198 - AR
1cs8_A_146 - AR
1cs8_A_105 - AR
1cs8_A_87 - AR
1cs8_A_198 - AR
1cs8_A_146 - AR
1cs8_A_105 - AR
1cs8_A_87 - AR
1cs8_A_56 - EH
1cs8_A_5 - EH
1cs8_A_180 - HA
1cs8_A_163 - HA
1cs8_A_83 - HA
1cs8_A_163 - HA
1cs8_A_83 - HA
1cs8_A_70 - HE
1cs8_A_141 - HE
1cs8_A_68 - HE
1cs8_A_9 - HH
1cs8_A_50 - HH

Homologous structures to 1cs8 classified in ArchDB

1cjl - - percentage of sequence identity: 98
1fh0 B - percentage of sequence identity: 79
1icf A - percentage of sequence identity: 99
1icf B - percentage of sequence identity: 100
1icf C - percentage of sequence identity: 99
1icf D - percentage of sequence identity: 100
1mhw B - percentage of sequence identity: 99
1mhw C - percentage of sequence identity: 100
1mhw D - percentage of sequence identity: 100