PDB: 1cu1 Compound: proteaseHELICASE NS3 Classification: HYDROLASE Entry date in PDB: 2000-08-23 Resolution [Å]: 2.50 R-Factor: 0.200

CHAIN: A SWISS-PROT/TREMBL: P26663    KEYWORD: 3D-structure    ATP-binding    Coat protein    Core protein    Envelope protein    Glycoprotein    Helicase    Hydrolase    Nonstructural protein    Polyprotein    RNA-directed RNA polymerase    Serine protease    Transferase    Transmembrane    EC: 2.7.7.48 SCOP: b.47.1.3 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral proteases    NS3 protease    Human hepatitis C virus (HCV), different isolates SCOP: b.47.1.3 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral proteases    NS3 protease    Human hepatitis C virus (HCV), different isolates SCOP: c.37.1.14 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    RNA helicase    HCV helicase domain    Human hepatitis C virus (HCV), different isolates SCOP: c.37.1.14 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    RNA helicase    HCV helicase domain    Human hepatitis C virus (HCV), different isolates GO:  viral capsid    viral envelope    ATP binding    ATP-dependent helicase activity    helicase activity    nucleic acid binding    RNA binding    RNA-directed RNA polymerase activity    serine-type peptidase activity    structural molecule activity    proteolysis and peptidolysis    transcription    viral genome replication    viral transformation    CHAIN: B SWISS-PROT/TREMBL: P26663    KEYWORD: 3D-structure    ATP-binding    Coat protein    Core protein    Envelope protein    Glycoprotein    Helicase    Hydrolase    Nonstructural protein    Polyprotein    RNA-directed RNA polymerase    Serine protease    Transferase    Transmembrane    EC: 2.7.7.48 SCOP: b.47.1.3 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral proteases    NS3 protease    Human hepatitis C virus (HCV), different isolates SCOP: b.47.1.3 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral proteases    NS3 protease    Human hepatitis C virus (HCV), different isolates SCOP: c.37.1.14 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    RNA helicase    HCV helicase domain    Human hepatitis C virus (HCV), different isolates SCOP: c.37.1.14 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    RNA helicase    HCV helicase domain    Human hepatitis C virus (HCV), different isolates GO:  viral capsid    viral envelope    ATP binding    ATP-dependent helicase activity    helicase activity    nucleic acid binding    RNA binding    RNA-directed RNA polymerase activity    serine-type peptidase activity    structural molecule activity    proteolysis and peptidolysis    transcription    viral genome replication    viral transformation

Image Source: PDB

Loops in ArchDB95 clusters

1cu1_A_51 - EH => SUBCLASS : 0.1.4
1cu1_A_406 - EH => SUBCLASS : 1.1.54
1cu1_A_363 - EH => SUBCLASS : 2.1.3
1cu1_A_363 - EH => SUBCLASS : 2.1.11
1cu1_A_445 - EH => SUBCLASS : 2.2.1
1cu1_A_5 - EH => SUBCLASS : 3.4.3
1cu1_A_488 - HH => SUBCLASS : 3.1.1
1cu1_A_488 - HH => SUBCLASS : 3.2.1
1cu1_A_544 - HH => SUBCLASS : 4.10.2
1cu1_A_33 - HA => SUBCLASS : 2.2.1
1cu1_A_103 - HA => SUBCLASS : 3.1.1
1cu1_A_73 - HA => SUBCLASS : 4.1.7
1cu1_A_113 - HA => SUBCLASS : 4.2.1
1cu1_A_142 - HA => SUBCLASS : 4.5.2

Loops not clustered in ArchDB

1cu1_A_336 - AR
1cu1_A_82 - AR
1cu1_A_123 - AR
1cu1_A_424 - AR
1cu1_A_317 - AR
1cu1_A_352 - AR
1cu1_A_198 - EH
1cu1_A_225 - EH
1cu1_A_265 - EH
1cu1_A_286 - EH
1cu1_A_471 - EH
1cu1_A_609 - EH
1cu1_A_163 - EH
1cu1_A_708 - HA
1cu1_A_596 - HA
1cu1_A_42 - HA
1cu1_A_150 - HA
1cu1_A_251 - HA
1cu1_A_347 - HA
1cu1_A_388 - HA
1cu1_A_430 - HA
1cu1_A_614 - HE
1cu1_A_558 - HE
1cu1_A_455 - HE
1cu1_A_414 - HE
1cu1_A_372 - HE
1cu1_A_297 - HE
1cu1_A_270 - HE
1cu1_A_232 - HE
1cu1_A_213 - HE
1cu1_A_172 - HE
1cu1_A_56 - HE
1cu1_A_13 - HE
1cu1_A_506 - HH
1cu1_A_529 - HH

1a1q A - percentage of sequence identity: 100
1a1q B - percentage of sequence identity: 100
1a1q C - percentage of sequence identity: 100
1a1r A - percentage of sequence identity: 89
1a1r B - percentage of sequence identity: 89
1a1v A - percentage of sequence identity: 94
1bt7 - - percentage of sequence identity: 99
1cu1 A - percentage of sequence identity: 100
1cu1 B - percentage of sequence identity: 100
1dxp A - percentage of sequence identity: 96
1dxp B - percentage of sequence identity: 96
1dxw A - percentage of sequence identity: 99
1dy8 A - percentage of sequence identity: 96
1dy8 B - percentage of sequence identity: 96
1dy9 A - percentage of sequence identity: 96
1dy9 B - percentage of sequence identity: 96
1hei A - percentage of sequence identity: 94
1hei B - percentage of sequence identity: 94
1jr6 A - percentage of sequence identity: 78
1jxp A - percentage of sequence identity: 99
1jxp B - percentage of sequence identity: 99
1n1l A - percentage of sequence identity: 88
1n1l B - percentage of sequence identity: 88
1ns3 A - percentage of sequence identity: 99
1ns3 B - percentage of sequence identity: 99
1onb A - percentage of sequence identity: 78
1rgq A - percentage of sequence identity: 88
1rgq B - percentage of sequence identity: 88
1rtl A - percentage of sequence identity: 88
1rtl B - percentage of sequence identity: 88
1w3c A - percentage of sequence identity: 96
1w3c B - percentage of sequence identity: 96
2f55 A - percentage of sequence identity: 96
2f55 B - percentage of sequence identity: 96
2f55 C - percentage of sequence identity: 96
2fm2 A - percentage of sequence identity: 89
2fm2 C - percentage of sequence identity: 89
8ohm - - percentage of sequence identity: 96