PDB: 1dmt Compound: neutral endopeptidase Classification: HYDROLASE Entry date in PDB: 2000-12-20 Resolution [Å]: 2.10 R-Factor: 0.195

CHAIN: A SWISS-PROT/TREMBL: P08473    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal-anchor    Transmembrane    Zinc    EC: 3.4.24.11 SCOP: d.92.1.4 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Neutral endopeptidase (neprilysin)    Neutral endopeptidase (neprilysin)    Human (Homo sapiens) GO:  membrane    metallopeptidase activity    neprilysin activity    zinc ion binding    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1dmt_A_462 - HE => SUBCLASS : 0.1.2
1dmt_A_608 - HE => SUBCLASS : 1.2.1
1dmt_A_295 - HE => SUBCLASS : 1.2.10
1dmt_A_544 - HA => SUBCLASS : 4.1.1
1dmt_A_629 - HA => SUBCLASS : 5.7.1
1dmt_A_695 - EH => SUBCLASS : 1.1.2
1dmt_A_342 - EH => SUBCLASS : 2.1.21
1dmt_A_342 - EH => SUBCLASS : 2.1.30
1dmt_A_714 - HH => SUBCLASS : 1.1.2
1dmt_A_714 - HH => SUBCLASS : 1.1.3
1dmt_A_145 - HH => SUBCLASS : 1.4.4
1dmt_A_348 - HH => SUBCLASS : 2.1.2
1dmt_A_419 - HH => SUBCLASS : 2.3.13
1dmt_A_238 - HH => SUBCLASS : 5.1.1
1dmt_A_435 - HH => SUBCLASS : 5.25.1

Loops in ArchDB95 clusters

1dmt_A_695 - EH => SUBCLASS : 1.1.5
1dmt_A_342 - EH => SUBCLASS : 2.1.18
1dmt_A_342 - EH => SUBCLASS : 2.1.29
1dmt_A_714 - HH => SUBCLASS : 1.1.1
1dmt_A_714 - HH => SUBCLASS : 1.1.4
1dmt_A_145 - HH => SUBCLASS : 1.4.2
1dmt_A_348 - HH => SUBCLASS : 2.1.3
1dmt_A_348 - HH => SUBCLASS : 2.1.5
1dmt_A_173 - HH => SUBCLASS : 2.1.41
1dmt_A_238 - HH => SUBCLASS : 5.1.1
1dmt_A_462 - HE => SUBCLASS : 0.1.3
1dmt_A_608 - HE => SUBCLASS : 1.3.3
1dmt_A_295 - HE => SUBCLASS : 2.6.9
1dmt_A_295 - HE => SUBCLASS : 2.7.9
1dmt_A_544 - HA => SUBCLASS : 4.1.1
1dmt_A_629 - HA => SUBCLASS : 5.7.1

Loops in ArchDB-EC clusters

1dmt_A_238 - HH => SUBCLASS : 5.1.1

Loops not clustered in ArchDB

1dmt_A_102 - EH
1dmt_A_636 - EH
1dmt_A_551 - EH
1dmt_A_476 - EH
1dmt_A_301 - EH
1dmt_A_210 - EH
1dmt_A_544 - HA
1dmt_A_201 - HA
1dmt_A_201 - HA
1dmt_A_629 - HA
1dmt_A_681 - HE
1dmt_A_506 - HE
1dmt_A_322 - HE
1dmt_A_183 - HE
1dmt_A_82 - HE
1dmt_A_699 - HH
1dmt_A_644 - HH
1dmt_A_577 - HH
1dmt_A_570 - HH
1dmt_A_489 - HH
1dmt_A_484 - HH
1dmt_A_406 - HH
1dmt_A_59 - HH
1dmt_A_105 - HH
1dmt_A_130 - HH
1dmt_A_154 - HH
1dmt_A_304 - HH
1dmt_A_363 - HH
1dmt_A_384 - HH
1dmt_A_391 - HH
1dmt_A_265 - HH

1r1h A - percentage of sequence identity: 100
1r1i A - percentage of sequence identity: 100
1r1j A - percentage of sequence identity: 100
1y8j A - percentage of sequence identity: 100