PDB: 1du3 Compound: death receptor 5 Classification: APOPTOSIS Entry date in PDB: 2000-09-27 Resolution [Å]: 2.20 R-Factor: 0.291

CHAIN: B SWISS-PROT/TREMBL: O14763    KEYWORD: 3D-structure    Alternative splicing    Apoptosis    Polymorphism    Receptor    Repeat    Signal    Transmembrane    SCOP: g.24.1.1 Small proteins    TNF receptor-like    TNF receptor-like    TNF receptor-like    Death receptor-5 (dr5) fragment    Human (Homo sapiens) SCOP: g.24.1.1 Small proteins    TNF receptor-like    TNF receptor-like    TNF receptor-like    Death receptor-5 (dr5) fragment    Human (Homo sapiens) SCOP: g.24.1.1 Small proteins    TNF receptor-like    TNF receptor-like    TNF receptor-like    Death receptor-5 (dr5) fragment    Human (Homo sapiens) GO:  protein binding    receptor activity    signal transduction    CHAIN: D SWISS-PROT/TREMBL: P50591    KEYWORD: 3D-structure    Apoptosis    Cytokine    Metal-binding    Signal-anchor    Transmembrane    Zinc    SCOP: b.22.1.1 All beta proteins    TNF-like    TNF-like    TNF-like    Apoptosis-2 ligand, apo2l/TRAIL    Human (Homo sapiens) GO:  membrane    tumor necrosis factor receptor binding    immune response    CHAIN: E SWISS-PROT/TREMBL: P50591    KEYWORD: 3D-structure    Apoptosis    Cytokine    Metal-binding    Signal-anchor    Transmembrane    Zinc    SCOP: b.22.1.1 All beta proteins    TNF-like    TNF-like    TNF-like    Apoptosis-2 ligand, apo2l/TRAIL    Human (Homo sapiens) GO:  membrane    tumor necrosis factor receptor binding    immune response    CHAIN: F SWISS-PROT/TREMBL: P50591    KEYWORD: 3D-structure    Apoptosis    Cytokine    Metal-binding    Signal-anchor    Transmembrane    Zinc    SCOP: b.22.1.1 All beta proteins    TNF-like    TNF-like    TNF-like    Apoptosis-2 ligand, apo2l/TRAIL    Human (Homo sapiens) GO:  membrane    tumor necrosis factor receptor binding    immune response    CHAIN: G SWISS-PROT/TREMBL: O14763    KEYWORD: 3D-structure    Alternative splicing    Apoptosis    Polymorphism    Receptor    Repeat    Signal    Transmembrane    SCOP: g.24.1.1 Small proteins    TNF receptor-like    TNF receptor-like    TNF receptor-like    Death receptor-5 (dr5) fragment    Human (Homo sapiens) SCOP: g.24.1.1 Small proteins    TNF receptor-like    TNF receptor-like    TNF receptor-like    Death receptor-5 (dr5) fragment    Human (Homo sapiens) SCOP: g.24.1.1 Small proteins    TNF receptor-like    TNF receptor-like    TNF receptor-like    Death receptor-5 (dr5) fragment    Human (Homo sapiens) GO:  protein binding    receptor activity    signal transduction    CHAIN: J SWISS-PROT/TREMBL: P50591    KEYWORD: 3D-structure    Apoptosis    Cytokine    Metal-binding    Signal-anchor    Transmembrane    Zinc    SCOP: b.22.1.1 All beta proteins    TNF-like    TNF-like    TNF-like    Apoptosis-2 ligand, apo2l/TRAIL    Human (Homo sapiens) GO:  membrane    tumor necrosis factor receptor binding    immune response    CHAIN: K SWISS-PROT/TREMBL: P50591    KEYWORD: 3D-structure    Apoptosis    Cytokine    Metal-binding    Signal-anchor    Transmembrane    Zinc    SCOP: b.22.1.1 All beta proteins    TNF-like    TNF-like    TNF-like    Apoptosis-2 ligand, apo2l/TRAIL    Human (Homo sapiens) GO:  membrane    tumor necrosis factor receptor binding    immune response    CHAIN: L SWISS-PROT/TREMBL: P50591    KEYWORD: 3D-structure    Apoptosis    Cytokine    Metal-binding    Signal-anchor    Transmembrane    Zinc    SCOP: b.22.1.1 All beta proteins    TNF-like    TNF-like    TNF-like    Apoptosis-2 ligand, apo2l/TRAIL    Human (Homo sapiens) GO:  membrane    tumor necrosis factor receptor binding    immune response

Image Source: PDB

Loops in ArchDB95 clusters

1du3_A_83 - AR => SUBCLASS : 1.1.1
1du3_A_83 - AR => SUBCLASS : 4.2.5
1du3_A_91 - HA => SUBCLASS : 2.2.21
1du3_A_32 - HA => SUBCLASS : 5.2.2
1du3_A_70 - HA => SUBCLASS : 8.7.1

Loops not clustered in ArchDB

1du3_A_41 - AR
1du3_A_61 - AR
1du3_A_49 - HA

1d0g R - percentage of sequence identity: 100
1d0g S - percentage of sequence identity: 100
1d0g T - percentage of sequence identity: 100
1d4v A - percentage of sequence identity: 100
1dg6 A - percentage of sequence identity: 99
1du3 A - percentage of sequence identity: 100
1du3 B - percentage of sequence identity: 100
1du3 C - percentage of sequence identity: 100
1du3 G - percentage of sequence identity: 100
1du3 H - percentage of sequence identity: 100
1du3 I - percentage of sequence identity: 100
1za3 R - percentage of sequence identity: 100
1za3 S - percentage of sequence identity: 100