PDB: 1dug Compound: chimera of glutathione s-transferase-synthetic lin Classification: TRANSFERASE, BLOOD CLOTTING Entry date in PDB: 2000-02-02 Resolution [Å]: 1.80 R-Factor: 0.185

CHAIN: A SWISS-PROT/TREMBL: P08515    KEYWORD: 3D-structure    Antigen    Multigene family    Transferase    3D-structure    Antigen    Multigene family    Transferase    3D-structure    Alternative splicing    Blood coagulation    Calcium    Disease mutation    Glycoprotein    Plasma    Platelet    Polymorphism    Signal    Sulfation    EC: 2.5.1.18 SCOP: a.45.1.1 All alpha proteins    Glutathione S-transferase (GST), C-terminal domain    Glutathione S-transferase (GST), C-terminal domain    Glutathione S-transferase (GST), C-terminal domain    Class alpha GST    Schistosoma japonicum SCOP: c.47.1.5 Alpha and beta proteins (a/b)    Thioredoxin fold    Thioredoxin-like    Glutathione S-transferase (GST), N-terminal domain    Class alpha GST    Schistosoma japonicum GO:  fibrinogen complex    platelet activation    protein polymerization    signal transduction    CHAIN: B SWISS-PROT/TREMBL: P08515    KEYWORD: 3D-structure    Antigen    Multigene family    Transferase    3D-structure    Antigen    Multigene family    Transferase    3D-structure    Alternative splicing    Blood coagulation    Calcium    Disease mutation    Glycoprotein    Plasma    Platelet    Polymorphism    Signal    Sulfation    EC: 2.5.1.18 SCOP: a.45.1.1 All alpha proteins    Glutathione S-transferase (GST), C-terminal domain    Glutathione S-transferase (GST), C-terminal domain    Glutathione S-transferase (GST), C-terminal domain    Class alpha GST    Schistosoma japonicum SCOP: c.47.1.5 Alpha and beta proteins (a/b)    Thioredoxin fold    Thioredoxin-like    Glutathione S-transferase (GST), N-terminal domain    Class alpha GST    Schistosoma japonicum GO:  fibrinogen complex    platelet activation    protein polymerization    signal transduction

Image Source: PDB

Loops in ArchDB40 clusters

1dug_A_14 - HE => SUBCLASS : 3.2.1
1dug_A_56 - HA => SUBCLASS : 2.2.1
1dug_A_28 - EH => SUBCLASS : 1.1.7
1dug_A_3 - EH => SUBCLASS : 4.42.1
1dug_A_67 - HH => SUBCLASS : 6.13.1
1dug_A_149 - HH => SUBCLASS : 8.4.1

Loops in ArchDB95 clusters

1dug_A_28 - EH => SUBCLASS : 1.1.12
1dug_A_3 - EH => SUBCLASS : 4.25.1
1dug_A_67 - HH => SUBCLASS : 6.5.1
1dug_A_149 - HH => SUBCLASS : 8.3.1
1dug_A_14 - HE => SUBCLASS : 3.5.1
1dug_A_37 - HE => SUBCLASS : 8.7.1
1dug_A_56 - HA => SUBCLASS : 2.2.1

Loops in ArchDB-EC clusters

1dug_A_149 - HH => SUBCLASS : 8.1.1

Loops not clustered in ArchDB

1dug_A_63 - EH
1dug_A_56 - HA
1dug_A_85 - HH
1dug_A_114 - HH
1dug_A_173 - HH

1b8x A - percentage of sequence identity: 100
1bg5 - - percentage of sequence identity: 100
1dug A - percentage of sequence identity: 100
1dug B - percentage of sequence identity: 100
1gne - - percentage of sequence identity: 100
1gta - - percentage of sequence identity: 100
1gtb - - percentage of sequence identity: 100
1m99 A - percentage of sequence identity: 100
1m9a A - percentage of sequence identity: 100
1m9b A - percentage of sequence identity: 100
1u87 A - percentage of sequence identity: 99
1u88 A - percentage of sequence identity: 99
1u88 B - percentage of sequence identity: 99
1ua5 A - percentage of sequence identity: 100
1y6e A - percentage of sequence identity: 100
1y6e B - percentage of sequence identity: 100
2fhe A - percentage of sequence identity: 60
2fhe B - percentage of sequence identity: 60