PDB: 1e8c Compound: udp-n-acetylmuramoylalanyl-d-glutamate--2,6- diami Classification: LIGASE Entry date in PDB: 2001-09-13 Resolution [Å]: 2.00 R-Factor: 0.202

CHAIN: A SWISS-PROT/TREMBL: P22188    KEYWORD: 3D-structure    ATP-binding    Cell division    Cell wall    Complete proteome    Ligase    Peptidoglycan synthesis    EC: 6.3.2.13 SCOP: c.98.1.1 Alpha and beta proteins (a/b)    MurF and HprK N-domain-like    MurE/MurF N-terminal domain    MurE/MurF N-terminal domain    UDP-N-acetylmuramyl tripeptide synthetase MurE    Escherichia coli SCOP: c.59.1.1 Alpha and beta proteins (a/b)    MurD-like peptide ligases, peptide-binding domain    MurD-like peptide ligases, peptide-binding domain    MurCDEF C-terminal domain    UDP-N-acetylmuramyl tripeptide synthetase MurE    Escherichia coli SCOP: c.72.2.1 Alpha and beta proteins (a/b)    Ribokinase-like    MurD-like peptide ligases, catalytic domain    MurCDEF    UDP-N-acetylmuramyl tripeptide synthetase MurE    Escherichia coli GO:  cytoplasm    acid-amino acid ligase activity    ATP binding    ligase activity    biosynthesis    cell wall biosynthesis (sensu Bacteria)    CHAIN: B SWISS-PROT/TREMBL: P22188    KEYWORD: 3D-structure    ATP-binding    Cell division    Cell wall    Complete proteome    Ligase    Peptidoglycan synthesis    EC: 6.3.2.13 SCOP: c.98.1.1 Alpha and beta proteins (a/b)    MurF and HprK N-domain-like    MurE/MurF N-terminal domain    MurE/MurF N-terminal domain    UDP-N-acetylmuramyl tripeptide synthetase MurE    Escherichia coli SCOP: c.59.1.1 Alpha and beta proteins (a/b)    MurD-like peptide ligases, peptide-binding domain    MurD-like peptide ligases, peptide-binding domain    MurCDEF C-terminal domain    UDP-N-acetylmuramyl tripeptide synthetase MurE    Escherichia coli SCOP: c.72.2.1 Alpha and beta proteins (a/b)    Ribokinase-like    MurD-like peptide ligases, catalytic domain    MurCDEF    UDP-N-acetylmuramyl tripeptide synthetase MurE    Escherichia coli GO:  cytoplasm    acid-amino acid ligase activity    ATP binding    ligase activity    biosynthesis    cell wall biosynthesis (sensu Bacteria)

Image Source: PDB

Loops in ArchDB40 clusters

1e8c_A_470 - HA => SUBCLASS : 2.3.1
1e8c_A_344 - HA => SUBCLASS : 5.28.1
1e8c_A_476 - EH => SUBCLASS : 0.1.52
1e8c_A_476 - EH => SUBCLASS : 1.1.50
1e8c_A_83 - EH => SUBCLASS : 2.6.4
1e8c_A_235 - EH => SUBCLASS : 3.1.1
1e8c_A_352 - EH => SUBCLASS : 4.24.3
1e8c_A_305 - HH => SUBCLASS : 3.3.1

Loops in ArchDB95 clusters

1e8c_A_476 - EH => SUBCLASS : 2.2.4
1e8c_A_83 - EH => SUBCLASS : 2.6.3
1e8c_A_235 - EH => SUBCLASS : 3.2.1
1e8c_A_352 - EH => SUBCLASS : 4.6.1
1e8c_A_305 - HH => SUBCLASS : 3.2.1
1e8c_A_119 - HE => SUBCLASS : 2.1.1
1e8c_A_399 - HE => SUBCLASS : 2.3.1
1e8c_A_399 - HE => SUBCLASS : 2.3.5
1e8c_A_51 - HE => SUBCLASS : 3.1.1
1e8c_A_161 - HE => SUBCLASS : 3.1.1
1e8c_A_51 - HE => SUBCLASS : 3.1.4
1e8c_A_243 - HE => SUBCLASS : 3.4.1
1e8c_A_243 - HE => SUBCLASS : 3.4.2
1e8c_A_361 - HE => SUBCLASS : 3.15.2
1e8c_A_361 - HE => SUBCLASS : 4.37.1
1e8c_A_470 - HA => SUBCLASS : 2.3.1

Loops in ArchDB-EC clusters

1e8c_A_305 - HH => SUBCLASS : 3.3.1

Loops not clustered in ArchDB

1e8c_A_61 - AR
1e8c_A_459 - AR
1e8c_A_61 - AR
1e8c_A_459 - AR
1e8c_A_407 - EH
1e8c_A_379 - EH
1e8c_A_296 - EH
1e8c_A_200 - EH
1e8c_A_178 - EH
1e8c_A_137 - EH
1e8c_A_109 - EH
1e8c_A_36 - EH
1e8c_A_285 - HA
1e8c_A_75 - HA
1e8c_A_256 - HA
1e8c_A_271 - HA
1e8c_A_285 - HA
1e8c_A_344 - HA
1e8c_A_271 - HA
1e8c_A_256 - HA
1e8c_A_75 - HA
1e8c_A_470 - HA
1e8c_A_5 - HE
1e8c_A_89 - HE
1e8c_A_185 - HE
1e8c_A_226 - HE
1e8c_A_325 - HE
1e8c_A_443 - HE
1e8c_A_211 - HH
1e8c_A_420 - HH
1e8c_A_219 - HH

1e8c A - percentage of sequence identity: 100
1e8c B - percentage of sequence identity: 100