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Information on 1ee4
PDB: 1ee4
Compound: karyopherin alpha
Classification: TRANSPORT PROTEIN
Entry date in PDB: 2000-03-29
Resolution [Å]: 2.10
R-Factor: 0.246


CHAIN: A
SWISS-PROT/TREMBL: Q02821
   KEYWORD: 3D-structure    Nuclear protein    Protein transport    Repeat    Transport   
SCOP: a.118.1.1 All alpha proteins    alpha-alpha superhelix    ARM repeat    Armadillo repeat    Karyopherin alpha    Baker's yeast (Saccharomyces cerevisiae)
GO:  binding    protein transporter activity    intracellular protein transport    protein-nucleus import   


CHAIN: B
SWISS-PROT/TREMBL: Q02821
   KEYWORD: 3D-structure    Nuclear protein    Protein transport    Repeat    Transport   
SCOP: a.118.1.1 All alpha proteins    alpha-alpha superhelix    ARM repeat    Armadillo repeat    Karyopherin alpha    Baker's yeast (Saccharomyces cerevisiae)
GO:  binding    protein transporter activity    intracellular protein transport    protein-nucleus import   


CHAIN: C
SWISS-PROT/TREMBL: P01106
   KEYWORD: 3D-structure    Activator    DNA-binding    Glycoprotein    Nuclear protein    Phosphorylation    Polymorphism    Proto-oncogene    Transcription regulation   
GO:  nucleus    transcription factor activity    transcription regulator activity    regulation of transcription    regulation of transcription, DNA-dependent   


CHAIN: D
SWISS-PROT/TREMBL: P01106
   KEYWORD: 3D-structure    Activator    DNA-binding    Glycoprotein    Nuclear protein    Phosphorylation    Polymorphism    Proto-oncogene    Transcription regulation   
GO:  nucleus    transcription factor activity    transcription regulator activity    regulation of transcription    regulation of transcription, DNA-dependent   


CHAIN: E
SWISS-PROT/TREMBL: P01106
   KEYWORD: 3D-structure    Activator    DNA-binding    Glycoprotein    Nuclear protein    Phosphorylation    Polymorphism    Proto-oncogene    Transcription regulation   
GO:  nucleus    transcription factor activity    transcription regulator activity    regulation of transcription    regulation of transcription, DNA-dependent   


CHAIN: F
SWISS-PROT/TREMBL: P01106
   KEYWORD: 3D-structure    Activator    DNA-binding    Glycoprotein    Nuclear protein    Phosphorylation    Polymorphism    Proto-oncogene    Transcription regulation   
GO:  nucleus    transcription factor activity    transcription regulator activity    regulation of transcription    regulation of transcription, DNA-dependent   
1ee4 Image
Image Source: PDB

Stored Loops of 1ee4

Loops in ArchDB40 clusters

1ee4_A_289 - HH => SUBCLASS : 1.3.1
1ee4_A_163 - HH => SUBCLASS : 1.3.1
1ee4_A_472 - HH => SUBCLASS : 1.3.1
1ee4_A_331 - HH => SUBCLASS : 1.3.1
1ee4_A_205 - HH => SUBCLASS : 1.3.3
1ee4_A_373 - HH => SUBCLASS : 1.3.3
1ee4_A_123 - HH => SUBCLASS : 1.3.3
1ee4_A_418 - HH => SUBCLASS : 1.3.4
1ee4_A_373 - HH => SUBCLASS : 1.3.14
1ee4_A_418 - HH => SUBCLASS : 1.3.16
1ee4_A_418 - HH => SUBCLASS : 1.3.18
1ee4_A_385 - HH => SUBCLASS : 2.1.18
1ee4_A_174 - HH => SUBCLASS : 2.1.18
1ee4_A_217 - HH => SUBCLASS : 2.4.5
1ee4_A_300 - HH => SUBCLASS : 3.4.1
1ee4_A_482 - HH => SUBCLASS : 3.4.1
1ee4_A_342 - HH => SUBCLASS : 3.4.1
1ee4_A_259 - HH => SUBCLASS : 3.4.1
1ee4_A_430 - HH => SUBCLASS : 3.4.1
1ee4_A_89 - HH => SUBCLASS : 3.4.2
1ee4_A_89 - HH => SUBCLASS : 3.4.3

Loops in ArchDB95 clusters

1ee4_A_289 - HH => SUBCLASS : 1.3.1
1ee4_A_472 - HH => SUBCLASS : 1.3.1
1ee4_A_373 - HH => SUBCLASS : 1.3.4
1ee4_A_205 - HH => SUBCLASS : 1.3.4
1ee4_A_331 - HH => SUBCLASS : 1.3.4
1ee4_A_123 - HH => SUBCLASS : 1.3.4
1ee4_A_418 - HH => SUBCLASS : 1.3.4
1ee4_A_331 - HH => SUBCLASS : 1.3.5
1ee4_A_163 - HH => SUBCLASS : 1.3.20
1ee4_A_145 - HH => SUBCLASS : 2.1.6
1ee4_A_355 - HH => SUBCLASS : 2.1.6
1ee4_A_313 - HH => SUBCLASS : 2.1.6
1ee4_A_385 - HH => SUBCLASS : 2.1.9
1ee4_A_217 - HH => SUBCLASS : 2.5.7
1ee4_A_300 - HH => SUBCLASS : 3.3.1
1ee4_A_482 - HH => SUBCLASS : 3.3.1
1ee4_A_89 - HH => SUBCLASS : 3.3.1
1ee4_A_259 - HH => SUBCLASS : 3.3.1
1ee4_A_430 - HH => SUBCLASS : 3.3.1
1ee4_A_342 - HH => SUBCLASS : 3.3.1
1ee4_A_430 - HH => SUBCLASS : 3.3.4
1ee4_A_132 - HH => SUBCLASS : 5.3.1

Loops not clustered in ArchDB

1ee4_A_101 - HH
1ee4_A_187 - HH
1ee4_A_229 - HH
1ee4_A_252 - HH
1ee4_A_271 - HH
1ee4_A_397 - HH
1ee4_A_442 - HH

Homologous structures to 1ee4 classified in ArchDB

1bk5 A - percentage of sequence identity: 99
1bk5 B - percentage of sequence identity: 99
1bk6 A - percentage of sequence identity: 99
1bk6 B - percentage of sequence identity: 99
1ee4 A - percentage of sequence identity: 100
1ee4 B - percentage of sequence identity: 100
1ee5 A - percentage of sequence identity: 100
1un0 A - percentage of sequence identity: 100
1un0 B - percentage of sequence identity: 100
1wa5 B - percentage of sequence identity: 99
2c1t A - percentage of sequence identity: 100
2c1t B - percentage of sequence identity: 100