PDB: 1ek6 Compound: udp-galactose 4-epimerase Classification: ISOMERASE Entry date in PDB: 2000-05-17 Resolution [Å]: 1.50 R-Factor: 0.169

CHAIN: A SWISS-PROT/TREMBL: Q14376    KEYWORD: 3D-structure    Disease mutation    Galactose metabolism    Isomerase    NAD    Polymorphism    EC: 5.1.3.2 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase)    Human (Homo sapiens) GO:  catalytic activity    NAD binding    racemase and epimerase activity, acting on carbohydrates and derivatives    UDP-glucose 4-epimerase activity    carbohydrate metabolism    galactose metabolism    nucleotide-sugar metabolism    CHAIN: B SWISS-PROT/TREMBL: Q14376    KEYWORD: 3D-structure    Disease mutation    Galactose metabolism    Isomerase    NAD    Polymorphism    EC: 5.1.3.2 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase)    Human (Homo sapiens) GO:  catalytic activity    NAD binding    racemase and epimerase activity, acting on carbohydrates and derivatives    UDP-glucose 4-epimerase activity    carbohydrate metabolism    galactose metabolism    nucleotide-sugar metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1ek6_A_61 - EH => SUBCLASS : 4.1.1
1ek6_A_4 - EH => SUBCLASS : 4.14.1
1ek6_A_264 - AR => SUBCLASS : 4.36.1

Loops in ArchDB95 clusters

1ek6_A_61 - EH => SUBCLASS : 4.1.1
1ek6_A_4 - EH => SUBCLASS : 4.7.1
1ek6_A_264 - AR => SUBCLASS : 2.8.2
1ek6_A_312 - HH => SUBCLASS : 7.5.1
1ek6_A_70 - HE => SUBCLASS : 0.1.4
1ek6_A_70 - HE => SUBCLASS : 0.1.5
1ek6_A_13 - HE => SUBCLASS : 2.1.1
1ek6_A_70 - HE => SUBCLASS : 2.6.1
1ek6_A_101 - HE => SUBCLASS : 3.1.1
1ek6_A_277 - HE => SUBCLASS : 3.2.3
1ek6_A_156 - HE => SUBCLASS : 3.4.2
1ek6_A_208 - HE => SUBCLASS : 4.4.1
1ek6_A_47 - HE => SUBCLASS : 5.10.1

Loops in ArchDB-EC clusters

1ek6_A_312 - HH => SUBCLASS : 7.5.1

Loops not clustered in ArchDB

1ek6_A_294 - AR
1ek6_A_264 - AR
1ek6_A_223 - AR
1ek6_A_179 - AR
1ek6_A_294 - AR
1ek6_A_223 - AR
1ek6_A_179 - AR
1ek6_A_29 - EH
1ek6_A_82 - EH
1ek6_A_126 - EH
1ek6_A_187 - EH
1ek6_A_241 - EH
1ek6_A_275 - EH
1ek6_A_306 - EH
1ek6_A_238 - HA
1ek6_A_238 - HA
1ek6_A_244 - HE
1ek6_A_94 - HH

1ek5 A - percentage of sequence identity: 100
1ek6 A - percentage of sequence identity: 100
1ek6 B - percentage of sequence identity: 100
1hzj A - percentage of sequence identity: 99
1hzj B - percentage of sequence identity: 99
1i3k A - percentage of sequence identity: 99
1i3k B - percentage of sequence identity: 99
1i3l A - percentage of sequence identity: 99
1i3l B - percentage of sequence identity: 99
1i3m A - percentage of sequence identity: 99
1i3m B - percentage of sequence identity: 99
1i3n A - percentage of sequence identity: 99
1i3n B - percentage of sequence identity: 99