PDB: 1fi8 Compound: natural killer cell protease 1 Classification: HYDROLASE/HYDROLASE INHIBITOR Entry date in PDB: 2000-09-13 Resolution [Å]: 2.20 R-Factor: 0.218

CHAIN: A SWISS-PROT/TREMBL: P18291    KEYWORD: 3D-structure    Cytolysis    Hydrolase    Serine protease    Signal    T-cell    Zymogen    EC: 3.4.21.- SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Granzyme B    Rat (Rattus norvegicus) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P18291    KEYWORD: 3D-structure    Cytolysis    Hydrolase    Serine protease    Signal    T-cell    Zymogen    EC: 3.4.21.- SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Granzyme B    Rat (Rattus norvegicus) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: D SWISS-PROT/TREMBL: P23827    KEYWORD: 3D-structure    Complete proteome    Periplasmic    Serine protease inhibitor    Signal    SCOP: b.16.1.1 All beta proteins    Ecotin, trypsin inhibitor    Ecotin, trypsin inhibitor    Ecotin, trypsin inhibitor    Ecotin, trypsin inhibitor    Escherichia coli GO:   CHAIN: F SWISS-PROT/TREMBL: P23827    KEYWORD: 3D-structure    Complete proteome    Periplasmic    Serine protease inhibitor    Signal    SCOP: b.16.1.1 All beta proteins    Ecotin, trypsin inhibitor    Ecotin, trypsin inhibitor    Ecotin, trypsin inhibitor    Ecotin, trypsin inhibitor    Escherichia coli GO:

Image Source: PDB

Loops in ArchDB95 clusters

1fi8_A_226 - EH => SUBCLASS : 0.1.2
1fi8_A_51 - AR => SUBCLASS : 7.7.1
1fi8_A_104 - AR => SUBCLASS : 26.1.1
1fi8_A_198 - HA => SUBCLASS : 2.1.2
1fi8_A_81 - HA => SUBCLASS : 12.1.1
1fi8_A_64 - HA => SUBCLASS : 12.2.1
1fi8_A_135 - HA => SUBCLASS : 14.4.1

Loops in ArchDB-EC clusters

1fi8_A_64 - HA => SUBCLASS : 12.2.1

Loops not clustered in ArchDB

1fi8_A_51 - AR
1fi8_A_20 - AR
1fi8_A_180 - AR
1fi8_A_104 - AR
1fi8_A_20 - AR
1fi8_A_180 - AR
1fi8_A_156 - EH
1fi8_A_135 - HA
1fi8_A_81 - HA
1fi8_A_198 - HA
1fi8_A_64 - HA
1fi8_A_41 - HA
1fi8_A_30 - HA
1fi8_A_204 - HA
1fi8_A_41 - HA
1fi8_A_30 - HA
1fi8_C_58 - HA
1fi8_A_204 - HA
1fi8_A_165 - HE

1euf A - percentage of sequence identity: 61
1ezs A - percentage of sequence identity: 93
1fi8 A - percentage of sequence identity: 100
1fi8 B - percentage of sequence identity: 100
1fq3 A - percentage of sequence identity: 69
1fq3 B - percentage of sequence identity: 69
1iau A - percentage of sequence identity: 70
1slu A - percentage of sequence identity: 98