PDB: 1fkn Compound: memapsin 2 Classification: HYDROLASE Entry date in PDB: 2000-10-09 Resolution [Å]: 1.90 R-Factor: 0.180

CHAIN: A SWISS-PROT/TREMBL: P56817    KEYWORD: 3D-structure    Alternative splicing    Aspartyl protease    Glycoprotein    Hydrolase    Signal    Transmembrane    Zymogen    EC: 3.4.23.46 SCOP: b.50.1.2 All beta proteins    Acid proteases    Acid proteases    Pepsin-like    beta-secretase (memapsin)    Human (Homo sapiens) GO:  aspartic-type endopeptidase activity    aspartic-type signal peptidase activity    pepsin A activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P56817    KEYWORD: 3D-structure    Alternative splicing    Aspartyl protease    Glycoprotein    Hydrolase    Signal    Transmembrane    Zymogen    EC: 3.4.23.46 SCOP: b.50.1.2 All beta proteins    Acid proteases    Acid proteases    Pepsin-like    beta-secretase (memapsin)    Human (Homo sapiens) GO:  aspartic-type endopeptidase activity    aspartic-type signal peptidase activity    pepsin A activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1fkn_A_341 - HA => SUBCLASS : 4.1.1
1fkn_A_283 - HA => SUBCLASS : 4.15.1
1fkn_A_13 - HA => SUBCLASS : 4.31.1
1fkn_A_294 - EH => SUBCLASS : 0.1.3
1fkn_A_294 - EH => SUBCLASS : 1.1.2
1fkn_A_294 - EH => SUBCLASS : 1.1.4
1fkn_A_25 - AR => SUBCLASS : 4.7.1
1fkn_A_225 - AR => SUBCLASS : 4.9.1

Loops in ArchDB95 clusters

1fkn_A_234 - EH => SUBCLASS : 0.1.4
1fkn_A_294 - EH => SUBCLASS : 1.1.5
1fkn_A_225 - AR => SUBCLASS : 4.7.1
1fkn_A_25 - AR => SUBCLASS : 5.2.1
1fkn_A_172 - AR => SUBCLASS : 7.15.1
1fkn_A_6 - HA => SUBCLASS : 3.3.9
1fkn_A_341 - HA => SUBCLASS : 4.1.1
1fkn_A_283 - HA => SUBCLASS : 4.12.1
1fkn_A_13 - HA => SUBCLASS : 4.15.2

Loops in ArchDB-EC clusters

1fkn_A_259 - HE => SUBCLASS : 4.49.1

Loops not clustered in ArchDB

1fkn_A_351 - AR
1fkn_A_318 - AR
1fkn_A_324 - AR
1fkn_A_351 - AR
1fkn_A_25 - AR
1fkn_A_38 - AR
1fkn_A_94 - AR
1fkn_A_172 - AR
1fkn_A_184 - AR
1fkn_A_211 - AR
1fkn_A_225 - AR
1fkn_A_268 - AR
1fkn_A_318 - AR
1fkn_A_324 - AR
1fkn_A_268 - AR
1fkn_A_211 - AR
1fkn_A_184 - AR
1fkn_A_94 - AR
1fkn_A_38 - AR
1fkn_A_150 - EH
1fkn_A_331 - EH
1fkn_A_117 - EH
1fkn_A_75 - HA
1fkn_A_305 - HA
1fkn_A_203 - HA
1fkn_A_305 - HA
1fkn_A_203 - HA
1fkn_A_341 - HA
1fkn_A_6 - HA
1fkn_A_13 - HA
1fkn_A_75 - HA
1fkn_A_61 - HA
1fkn_A_61 - HA
1fkn_A_283 - HA
1fkn_A_136 - HE
1fkn_A_163 - HE
1fkn_A_302 - HE
1fkn_A_335 - HE
1fkn_A_238 - HH

1fkn A - percentage of sequence identity: 100
1fkn B - percentage of sequence identity: 100
1m4h A - percentage of sequence identity: 100
1m4h B - percentage of sequence identity: 100
1sgz A - percentage of sequence identity: 100
1sgz B - percentage of sequence identity: 100
1sgz C - percentage of sequence identity: 100
1sgz D - percentage of sequence identity: 100
1tqf A - percentage of sequence identity: 99
1w50 A - percentage of sequence identity: 99
1w51 A - percentage of sequence identity: 99
1xn2 A - percentage of sequence identity: 100
1xn2 B - percentage of sequence identity: 100
1xn2 C - percentage of sequence identity: 100
1xn2 D - percentage of sequence identity: 100
1xn3 A - percentage of sequence identity: 100
1xn3 B - percentage of sequence identity: 100
1xn3 C - percentage of sequence identity: 100
1xn3 D - percentage of sequence identity: 100
1xs7 D - percentage of sequence identity: 100
1ym2 A - percentage of sequence identity: 100
1ym2 B - percentage of sequence identity: 100
1ym2 C - percentage of sequence identity: 100
1ym4 A - percentage of sequence identity: 100
1ym4 B - percentage of sequence identity: 100
1ym4 C - percentage of sequence identity: 100
2b8l A - percentage of sequence identity: 99
2b8v A - percentage of sequence identity: 99
2fdp A - percentage of sequence identity: 100
2fdp B - percentage of sequence identity: 100
2fdp C - percentage of sequence identity: 100