PDB: 1fmc Compound: 7 alpha-hydroxysteroid dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 1996-11-08 Resolution [Å]: 1.80 R-Factor: 0.207

CHAIN: A SWISS-PROT/TREMBL: P25529    KEYWORD: 3D-structure    Bile acid catabolism    Complete proteome    NAD    Oxidoreductase    EC: 1.1.1.159 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    7-alpha-hydroxysteroid dehydrogenase    Escherichia coli GO:  oxidoreductase activity    oxidoreductase activity    metabolism    metabolism    CHAIN: B SWISS-PROT/TREMBL: P25529    KEYWORD: 3D-structure    Bile acid catabolism    Complete proteome    NAD    Oxidoreductase    EC: 1.1.1.159 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    7-alpha-hydroxysteroid dehydrogenase    Escherichia coli GO:  oxidoreductase activity    oxidoreductase activity    metabolism    metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1fmc_A_37 - EH => SUBCLASS : 2.1.1
1fmc_A_62 - EH => SUBCLASS : 4.1.1
1fmc_A_13 - EH => SUBCLASS : 5.13.1
1fmc_A_182 - EH => SUBCLASS : 5.29.1
1fmc_A_139 - EH => SUBCLASS : 11.1.1
1fmc_A_195 - HH => SUBCLASS : 2.1.9

Loops in ArchDB95 clusters

1fmc_A_37 - EH => SUBCLASS : 2.1.1
1fmc_A_37 - EH => SUBCLASS : 2.1.8
1fmc_A_62 - EH => SUBCLASS : 4.1.1
1fmc_A_13 - EH => SUBCLASS : 5.17.1
1fmc_A_182 - EH => SUBCLASS : 5.34.1
1fmc_A_139 - EH => SUBCLASS : 11.1.1
1fmc_A_22 - HE => SUBCLASS : 1.1.1
1fmc_A_45 - HE => SUBCLASS : 2.1.1
1fmc_A_221 - HE => SUBCLASS : 9.1.1

Loops in ArchDB-EC clusters

1fmc_A_195 - HH => SUBCLASS : 2.1.6

Loops not clustered in ArchDB

1fmc_A_91 - EH
1fmc_A_72 - HE
1fmc_A_120 - HE
1fmc_A_157 - HE
1fmc_A_108 - HH
1fmc_A_203 - HH

1ahh A - percentage of sequence identity: 100
1ahh B - percentage of sequence identity: 100
1ahi A - percentage of sequence identity: 100
1ahi B - percentage of sequence identity: 100
1fmc A - percentage of sequence identity: 100
1fmc B - percentage of sequence identity: 100