PDB: 1h6v Compound: thioredoxin reductase Classification: OXIDOREDUCTASE Entry date in PDB: 2001-08-14 Resolution [Å]: 3.00 R-Factor: 0.226

CHAIN: A SWISS-PROT/TREMBL: O89049    KEYWORD: FAD    Flavoprotein    Oxidoreductase    Redox-active center    EC: 1.8.1.9 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) GO:  cytoplasm    disulfide oxidoreductase activity    FAD binding    oxidoreductase activity    oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor    electron transport    CHAIN: B SWISS-PROT/TREMBL: O89049    KEYWORD: FAD    Flavoprotein    Oxidoreductase    Redox-active center    EC: 1.8.1.9 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) GO:  cytoplasm    disulfide oxidoreductase activity    FAD binding    oxidoreductase activity    oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor    electron transport    CHAIN: C SWISS-PROT/TREMBL: O89049    KEYWORD: FAD    Flavoprotein    Oxidoreductase    Redox-active center    EC: 1.8.1.9 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) GO:  cytoplasm    disulfide oxidoreductase activity    FAD binding    oxidoreductase activity    oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor    electron transport    CHAIN: D SWISS-PROT/TREMBL: O89049    KEYWORD: FAD    Flavoprotein    Oxidoreductase    Redox-active center    EC: 1.8.1.9 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) GO:  cytoplasm    disulfide oxidoreductase activity    FAD binding    oxidoreductase activity    oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor    electron transport    CHAIN: E SWISS-PROT/TREMBL: O89049    KEYWORD: FAD    Flavoprotein    Oxidoreductase    Redox-active center    EC: 1.8.1.9 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) GO:  cytoplasm    disulfide oxidoreductase activity    FAD binding    oxidoreductase activity    oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor    electron transport    CHAIN: F SWISS-PROT/TREMBL: O89049    KEYWORD: FAD    Flavoprotein    Oxidoreductase    Redox-active center    EC: 1.8.1.9 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Mammalian thioredoxin reductase    Rat (Rattus norvegicus) GO:  cytoplasm    disulfide oxidoreductase activity    FAD binding    oxidoreductase activity    oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor    electron transport

Image Source: PDB

Loops in ArchDB-EC clusters

1h6v_A_445 - HH => SUBCLASS : 3.3.1

Loops not clustered in ArchDB

1h6v_A_126 - AR
1h6v_A_149 - AR
1h6v_A_245 - AR
1h6v_A_278 - AR
1h6v_A_286 - AR
1h6v_A_293 - AR
1h6v_A_380 - EH
1h6v_A_38 - EH
1h6v_A_163 - EH
1h6v_A_13 - EH
1h6v_A_193 - EH
1h6v_A_216 - EH
1h6v_A_329 - EH
1h6v_A_434 - EH
1h6v_A_399 - EH
1h6v_A_372 - HA
1h6v_A_252 - HA
1h6v_A_139 - HA
1h6v_A_131 - HA
1h6v_A_266 - HA
1h6v_A_421 - HA
1h6v_A_409 - HE
1h6v_A_22 - HE
1h6v_A_98 - HE
1h6v_A_180 - HE
1h6v_A_200 - HE
1h6v_A_230 - HE
1h6v_A_343 - HE
1h6v_A_387 - HE
1h6v_A_57 - HH
1h6v_A_64 - HH
1h6v_A_173 - HH

1h6v A - percentage of sequence identity: 100
1h6v B - percentage of sequence identity: 100
1h6v C - percentage of sequence identity: 100
1h6v D - percentage of sequence identity: 100
1h6v E - percentage of sequence identity: 100
1h6v F - percentage of sequence identity: 100