PDB: 1hwg Compound: growth hormone Classification: COMPLEX (HORMONE/RECEPTOR) Entry date in PDB: 1997-11-19 Resolution [Å]: 2.50 R-Factor: 0.199

CHAIN: A SWISS-PROT/TREMBL: P01241    KEYWORD: 3D-structure    Alternative splicing    Disease mutation    Dwarfism    Hormone    Pharmaceutical    Phosphorylation    Pituitary    Polymorphism    Signal    SCOP: a.26.1.1 All alpha proteins    4-helical cytokines    4-helical cytokines    Long-chain cytokines    Growth hormone, somatotropin    Human (Homo sapiens) GO:  extracellular region    hormone activity    CHAIN: B SWISS-PROT/TREMBL: P10912    KEYWORD: 3D-structure    Alternative splicing    Disease mutation    Dwarfism    Endocytosis    Glycoprotein    Phosphorylation    Polymorphism    Receptor    Signal    Transmembrane    Ubl conjugation    SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Growth hormone receptor    Human (Homo sapiens) SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Growth hormone receptor    Human (Homo sapiens) GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity    CHAIN: C SWISS-PROT/TREMBL: P10912    KEYWORD: 3D-structure    Alternative splicing    Disease mutation    Dwarfism    Endocytosis    Glycoprotein    Phosphorylation    Polymorphism    Receptor    Signal    Transmembrane    Ubl conjugation    SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Growth hormone receptor    Human (Homo sapiens) SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Growth hormone receptor    Human (Homo sapiens) GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity

Image Source: PDB

1axi B - percentage of sequence identity: 98
1huw - - percentage of sequence identity: 92