PDB: 1hye Compound: l-lactateMALATE DEHYDROGENASE Classification: OXIDOREDUCTASE Entry date in PDB: 2001-04-18 Resolution [Å]: 1.90 R-Factor: 0.194

CHAIN: A SWISS-PROT/TREMBL: Q60176    KEYWORD: 3D-structure    Complete proteome    NAD    NADP    Oxidoreductase    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    MJ0490, lactate/malate dehydrogenase    Archaeon Methanococcus jannaschii SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    MJ0490, lactate/malate dehydrogenase    Archaeon Methanococcus jannaschii GO:  cytoplasm    L-lactate dehydrogenase activity    oxidoreductase activity    anaerobic glycolysis    glycolysis    tricarboxylic acid cycle intermediate metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1hye_A_265 - HA => SUBCLASS : 2.2.15
1hye_A_174 - HA => SUBCLASS : 7.17.1
1hye_A_28 - EH => SUBCLASS : 1.1.7
1hye_A_143 - EH => SUBCLASS : 2.7.2
1hye_A_2 - EH => SUBCLASS : 4.14.1
1hye_A_117 - EH => SUBCLASS : 4.28.1
1hye_A_279 - EH => SUBCLASS : 6.12.1
1hye_A_182 - AR => SUBCLASS : 5.2.1

Loops in ArchDB95 clusters

1hye_A_28 - EH => SUBCLASS : 1.2.2
1hye_A_143 - EH => SUBCLASS : 2.7.2
1hye_A_2 - EH => SUBCLASS : 4.7.1
1hye_A_117 - EH => SUBCLASS : 4.17.1
1hye_A_279 - EH => SUBCLASS : 6.8.1
1hye_A_182 - AR => SUBCLASS : 3.2.1
1hye_A_232 - HE => SUBCLASS : 3.17.1
1hye_A_92 - HE => SUBCLASS : 3.37.1
1hye_A_11 - HE => SUBCLASS : 5.2.5
1hye_A_149 - HE => SUBCLASS : 6.1.1
1hye_A_125 - HE => SUBCLASS : 6.2.1
1hye_A_265 - HA => SUBCLASS : 2.2.22
1hye_A_174 - HA => SUBCLASS : 7.10.1

Loops in ArchDB-EC clusters

1hye_A_149 - HE => SUBCLASS : 6.2.1

Loops not clustered in ArchDB

1hye_A_170 - AR
1hye_A_60 - AR
1hye_A_182 - AR
1hye_A_170 - AR
1hye_A_60 - AR
1hye_A_194 - EH
1hye_A_77 - EH
1hye_A_190 - HA
1hye_A_249 - HA
1hye_A_174 - HA
1hye_A_249 - HA
1hye_A_190 - HA
1hye_A_265 - HA
1hye_A_38 - HE
1hye_A_207 - HH

1hyg A - percentage of sequence identity: 100
1hyg B - percentage of sequence identity: 100