PDB: 1i50 Compound: DNA-directed RNA polymerase ii largest subunit Classification: TRANSCRIPTION Entry date in PDB: 2001-04-23 Resolution [Å]: 2.80 R-Factor: 0.229

CHAIN: A SWISS-PROT/TREMBL: P04050    KEYWORD: 3D-structure    DNA-binding    DNA-directed RNA polymerase    Nuclear protein    Phosphorylation    Repeat    Transcription    Transferase    Zinc    Zinc-finger    EC: 2.7.7.6 SCOP: e.29.1.2 Multi-domain proteins (alpha and beta)    beta and beta-prime subunits of DNA dependent RNA-polymerase    beta and beta-prime subunits of DNA dependent RNA-polymerase    RNA-polymerase beta-prime    RBP1    Baker's yeast (Saccharomyces cerevisiae) GO:  DNA-directed RNA polymerase II, core complex    nucleus    DNA binding    DNA-directed RNA polymerase activity    transcription    transcription from RNA polymerase II promoter    CHAIN: B SWISS-PROT/TREMBL: P08518    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Nuclear protein    Transcription    Transferase    Zinc    Zinc-finger    EC: 2.7.7.6 SCOP: e.29.1.1 Multi-domain proteins (alpha and beta)    beta and beta-prime subunits of DNA dependent RNA-polymerase    beta and beta-prime subunits of DNA dependent RNA-polymerase    RNA-polymerase beta    RBP2    Baker's yeast (Saccharomyces cerevisiae) GO:  DNA binding    DNA-directed RNA polymerase activity    transcription    CHAIN: C SWISS-PROT/TREMBL: P16370    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Nuclear protein    Transcription    Transferase    EC: 2.7.7.6 SCOP: d.74.3.1 Alpha and beta proteins (a+b)    DCoH-like    RBP11-like subunits of RNA polymerase    RNA polymerase alpha subunit dimerisation domain    RPB3    Baker's yeast (Saccharomyces cerevisiae) SCOP: d.74.3.1 Alpha and beta proteins (a+b)    DCoH-like    RBP11-like subunits of RNA polymerase    RNA polymerase alpha subunit dimerisation domain    RPB3    Baker's yeast (Saccharomyces cerevisiae) SCOP: d.181.1.1 Alpha and beta proteins (a+b)    Insert subdomain of RNA polymerase alpha subunit    Insert subdomain of RNA polymerase alpha subunit    Insert subdomain of RNA polymerase alpha subunit    RPB3    Baker's yeast (Saccharomyces cerevisiae) GO:  nucleus    DNA binding    DNA-directed RNA polymerase activity    protein dimerization activity    transcription    CHAIN: E SWISS-PROT/TREMBL: P20434    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Nuclear protein    Transcription    Transferase    EC: 2.7.7.6 SCOP: c.52.3.1 Alpha and beta proteins (a/b)    Restriction endonuclease-like    Eukaryotic RPB5 N-terminal domain    Eukaryotic RPB5 N-terminal domain    Eukaryotic RPB5 N-terminal domain    Baker's yeast (Saccharomyces cerevisiae) SCOP: d.78.1.1 Alpha and beta proteins (a+b)    RPB5-like RNA polymerase subunit    RPB5-like RNA polymerase subunit    RPB5    Eukaryotic RPB5 C-terminal domain    Baker's yeast (Saccharomyces cerevisiae) GO:  DNA binding    DNA-directed RNA polymerase activity    transcription    CHAIN: F SWISS-PROT/TREMBL: P20435    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Nuclear protein    Transcription    Transferase    EC: 2.7.7.6 SCOP: d.78.1.2 Alpha and beta proteins (a+b)    RPB5-like RNA polymerase subunit    RPB5-like RNA polymerase subunit    RPB6    RPB6    Baker's yeast (Saccharomyces cerevisiae) GO:  RNA polymerase complex    DNA binding    DNA-directed RNA polymerase activity    regulation of transcription    transcription, DNA-dependent    CHAIN: H SWISS-PROT/TREMBL: P20436    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Nuclear protein    Transcription    Transferase    EC: 2.7.7.6 SCOP: b.40.4.8 All beta proteins    OB-fold    Nucleic acid-binding proteins    RNA polymerase subunit RBP8    RNA polymerase subunit RBP8    Baker's yeast (Saccharomyces cerevisiae) GO:  transcription    CHAIN: I SWISS-PROT/TREMBL: P27999    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Nuclear protein    Transcription    Transferase    Zinc-finger    EC: 2.7.7.6 SCOP: g.41.3.1 Small proteins    Rubredoxin-like    Zinc beta-ribbon    Transcriptional factor domain    RBP9 subunit of RNA polymerase II    Baker's yeast (Saccharomyces cerevisiae) SCOP: g.41.3.1 Small proteins    Rubredoxin-like    Zinc beta-ribbon    Transcriptional factor domain    RBP9 subunit of RNA polymerase II    Baker's yeast (Saccharomyces cerevisiae) GO:  DNA binding    DNA-directed RNA polymerase activity    transcription factor activity    regulation of transcription, DNA-dependent    RNA elongation    transcription    CHAIN: J SWISS-PROT/TREMBL: P22139    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Metal-binding    Nuclear protein    Transcription    Transferase    Zinc    EC: 2.7.7.6 SCOP: a.4.11.1 All alpha proteins    DNA/RNA-binding 3-helical bundle    RNA polymerase subunit RPB10    RNA polymerase subunit RPB10    RNA polymerase subunit RPB10    Baker's yeast (Saccharomyces cerevisiae) GO:  DNA binding    DNA-directed RNA polymerase activity    regulation of transcription    transcription    CHAIN: K SWISS-PROT/TREMBL: P38902    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Nuclear protein    Transcription    Transferase    EC: 2.7.7.6 SCOP: d.74.3.2 Alpha and beta proteins (a+b)    DCoH-like    RBP11-like subunits of RNA polymerase    RPB11    RPB11    Baker's yeast (Saccharomyces cerevisiae) GO:  DNA binding    DNA-directed RNA polymerase activity    protein dimerization activity    transcription    CHAIN: L SWISS-PROT/TREMBL: P40422    KEYWORD: 3D-structure    DNA-directed RNA polymerase    Metal-binding    Nuclear protein    Transcription    Transferase    Zinc-finger    EC: 2.7.7.6 SCOP: g.41.9.2 Small proteins    Rubredoxin-like    RBP12 subunit of RNA polymerase II    RBP12 subunit of RNA polymerase II    RBP12 subunit of RNA polymerase II    Baker's yeast (Saccharomyces cerevisiae) GO:  nucleus    DNA binding    DNA-directed RNA polymerase activity    transcription

Image Source: PDB

Loops in ArchDB-EC clusters

1i50_J_32 - HH => SUBCLASS : 4.5.1

Loops not clustered in ArchDB

1i50_I_35 - AR
1i50_B_1001 - AR
1i50_B_987 - AR
1i50_B_962 - AR
1i50_B_935 - AR
1i50_B_853 - AR
1i50_B_821 - AR
1i50_B_804 - AR
1i50_B_792 - AR
1i50_B_564 - AR
1i50_B_536 - AR
1i50_B_214 - AR
1i50_B_208 - AR
1i50_B_1069 - AR
1i50_B_1072 - AR
1i50_H_54 - AR
1i50_H_121 - AR
1i50_H_95 - AR
1i50_H_37 - AR
1i50_C_152 - AR
1i50_C_143 - AR
1i50_C_129 - AR
1i50_C_119 - AR
1i50_C_111 - AR
1i50_C_97 - AR
1i50_C_72 - AR
1i50_B_1179 - AR
1i50_B_1157 - AR
1i50_B_623 - AR
1i50_B_1085 - EH
1i50_B_633 - EH
1i50_B_404 - EH
1i50_C_17 - EH
1i50_B_1191 - EH
1i50_B_480 - EH
1i50_B_544 - EH
1i50_B_585 - EH
1i50_B_1042 - EH
1i50_B_690 - EH
1i50_B_740 - EH
1i50_B_838 - EH
1i50_C_173 - EH
1i50_B_280 - EH
1i50_K_70 - EH
1i50_K_30 - EH
1i50_B_1010 - EH
1i50_B_110 - EH
1i50_C_228 - EH
1i50_C_43 - EH
1i50_B_166 - EH
1i50_B_910 - HA
1i50_B_979 - HA
1i50_B_234 - HA
1i50_B_948 - HA
1i50_B_1172 - HA
1i50_F_133 - HA
1i50_K_56 - HA
1i50_K_19 - HA
1i50_I_99 - HA
1i50_I_83 - HA
1i50_I_70 - HA
1i50_I_24 - HA
1i50_I_15 - HA
1i50_H_100 - HA
1i50_B_125 - HA
1i50_H_23 - HA
1i50_H_9 - HA
1i50_B_703 - HA
1i50_B_224 - HA
1i50_B_203 - HA
1i50_B_253 - HA
1i50_B_269 - HA
1i50_B_497 - HA
1i50_B_91 - HA
1i50_H_112 - HA
1i50_B_578 - HA
1i50_B_614 - HA
1i50_F_117 - HE
1i50_B_681 - HE
1i50_K_40 - HE
1i50_C_197 - HE
1i50_C_60 - HE
1i50_C_27 - HE
1i50_B_1052 - HE
1i50_B_1023 - HE
1i50_B_843 - HE
1i50_B_764 - HE
1i50_B_695 - HE
1i50_B_1144 - HE
1i50_B_114 - HE
1i50_B_552 - HE
1i50_B_186 - HE
1i50_B_488 - HE
1i50_B_593 - HE
1i50_B_451 - HE
1i50_B_371 - HE
1i50_B_58 - HE
1i50_B_45 - HH
1i50_B_655 - HH
1i50_J_44 - HH
1i50_J_18 - HH
1i50_B_409 - HH
1i50_B_345 - HH
1i50_B_327 - HH
1i50_B_308 - HH
1i50_B_294 - HH
1i50_B_282 - HH
1i50_F_87 - HH
1i50_B_30 - HH
1i50_B_1132 - HH

1dzf A - percentage of sequence identity: 100
1i3q C - percentage of sequence identity: 100
1i6h C - percentage of sequence identity: 100
1k83 C - percentage of sequence identity: 100
1nik C - percentage of sequence identity: 100
1nt9 C - percentage of sequence identity: 100
1pqv C - percentage of sequence identity: 100
1r5u C - percentage of sequence identity: 100
1r9s C - percentage of sequence identity: 100
1r9t C - percentage of sequence identity: 100
1sfo C - percentage of sequence identity: 100
1twa C - percentage of sequence identity: 100
1twc C - percentage of sequence identity: 100
1twf C - percentage of sequence identity: 100
1twg C - percentage of sequence identity: 100
1twh C - percentage of sequence identity: 100
1wcm C - percentage of sequence identity: 100
1y1v C - percentage of sequence identity: 100
1y1w C - percentage of sequence identity: 100
1y1y C - percentage of sequence identity: 100
1y77 C - percentage of sequence identity: 100
2b63 C - percentage of sequence identity: 100
null nu - percentage of sequence identity: 0