PDB: 1jbq Compound: cystathionine beta-synthase Classification: LYASE Entry date in PDB: 2001-08-12 Resolution [Å]: 2.60 R-Factor: 0.257

CHAIN: A SWISS-PROT/TREMBL: P35520    KEYWORD: 3D-structure    Alternative splicing    CBS domain    Cysteine biosynthesis    Disease mutation    Heme    Iron    Lyase    Pyridoxal phosphate    EC: 4.2.1.22 SCOP: c.79.1.1 Alpha and beta proteins (a/b)    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Cystathionine beta-synthase    Human (Homo sapiens) GO:  cytoplasm    catalytic activity    cystathionine beta-synthase activity    cysteine biosynthesis from serine    cysteine biosynthesis via cystathione    metabolism    CHAIN: B SWISS-PROT/TREMBL: P35520    KEYWORD: 3D-structure    Alternative splicing    CBS domain    Cysteine biosynthesis    Disease mutation    Heme    Iron    Lyase    Pyridoxal phosphate    EC: 4.2.1.22 SCOP: c.79.1.1 Alpha and beta proteins (a/b)    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Cystathionine beta-synthase    Human (Homo sapiens) GO:  cytoplasm    catalytic activity    cystathionine beta-synthase activity    cysteine biosynthesis from serine    cysteine biosynthesis via cystathione    metabolism    CHAIN: C SWISS-PROT/TREMBL: P35520    KEYWORD: 3D-structure    Alternative splicing    CBS domain    Cysteine biosynthesis    Disease mutation    Heme    Iron    Lyase    Pyridoxal phosphate    EC: 4.2.1.22 SCOP: c.79.1.1 Alpha and beta proteins (a/b)    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Cystathionine beta-synthase    Human (Homo sapiens) GO:  cytoplasm    catalytic activity    cystathionine beta-synthase activity    cysteine biosynthesis from serine    cysteine biosynthesis via cystathione    metabolism    CHAIN: D SWISS-PROT/TREMBL: P35520    KEYWORD: 3D-structure    Alternative splicing    CBS domain    Cysteine biosynthesis    Disease mutation    Heme    Iron    Lyase    Pyridoxal phosphate    EC: 4.2.1.22 SCOP: c.79.1.1 Alpha and beta proteins (a/b)    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Cystathionine beta-synthase    Human (Homo sapiens) GO:  cytoplasm    catalytic activity    cystathionine beta-synthase activity    cysteine biosynthesis from serine    cysteine biosynthesis via cystathione    metabolism    CHAIN: E SWISS-PROT/TREMBL: P35520    KEYWORD: 3D-structure    Alternative splicing    CBS domain    Cysteine biosynthesis    Disease mutation    Heme    Iron    Lyase    Pyridoxal phosphate    EC: 4.2.1.22 SCOP: c.79.1.1 Alpha and beta proteins (a/b)    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Cystathionine beta-synthase    Human (Homo sapiens) GO:  cytoplasm    catalytic activity    cystathionine beta-synthase activity    cysteine biosynthesis from serine    cysteine biosynthesis via cystathione    metabolism    CHAIN: F SWISS-PROT/TREMBL: P35520    KEYWORD: 3D-structure    Alternative splicing    CBS domain    Cysteine biosynthesis    Disease mutation    Heme    Iron    Lyase    Pyridoxal phosphate    EC: 4.2.1.22 SCOP: c.79.1.1 Alpha and beta proteins (a/b)    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Tryptophan synthase beta subunit-like PLP-dependent enzymes    Cystathionine beta-synthase    Human (Homo sapiens) GO:  cytoplasm    catalytic activity    cystathionine beta-synthase activity    cysteine biosynthesis from serine    cysteine biosynthesis via cystathione    metabolism

Image Source: PDB

Loops in ArchDB-EC clusters

1jbq_A_328 - HH => SUBCLASS : 5.8.1

Loops not clustered in ArchDB

1jbq_A_89 - EH
1jbq_A_104 - EH
1jbq_A_141 - EH
1jbq_A_164 - EH
1jbq_A_187 - EH
1jbq_A_217 - EH
1jbq_A_250 - EH
1jbq_A_322 - EH
1jbq_A_369 - EH
1jbq_A_276 - HA
1jbq_A_119 - HE
1jbq_A_149 - HE
1jbq_A_175 - HE
1jbq_A_203 - HE
1jbq_A_236 - HE
1jbq_A_259 - HE
1jbq_A_348 - HE
1jbq_A_95 - HE
1jbq_A_227 - HH

1jbq A - percentage of sequence identity: 100
1jbq B - percentage of sequence identity: 100
1jbq C - percentage of sequence identity: 100
1jbq D - percentage of sequence identity: 100
1jbq E - percentage of sequence identity: 100
1jbq F - percentage of sequence identity: 100
1m54 A - percentage of sequence identity: 99
1m54 B - percentage of sequence identity: 99
1m54 C - percentage of sequence identity: 99
1m54 D - percentage of sequence identity: 99
1m54 E - percentage of sequence identity: 99
1m54 F - percentage of sequence identity: 99