PDB: 1jtv Compound: 17 beta-hydroxysteroid dehydrogenase type 1 Classification: OXIDOREDUCTASE Entry date in PDB: 2003-06-24 Resolution [Å]: 1.54 R-Factor: 0.196

CHAIN: A SWISS-PROT/TREMBL: P14061    KEYWORD: 3D-structure    Multigene family    NAD    Oxidoreductase    Polymorphism    Steroid biosynthesis    EC: 1.1.1.62 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Human estrogenic 17beta-hydroxysteroid dehydrogenase    Human (Homo sapiens) GO:  cytoplasm    estradiol 17-beta-dehydrogenase activity    oxidoreductase activity    estrogen biosynthesis    metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1jtv_A_59 - EH => SUBCLASS : 4.1.1
1jtv_A_3 - EH => SUBCLASS : 5.13.1
1jtv_A_86 - EH => SUBCLASS : 14.1.1
1jtv_A_200 - HH => SUBCLASS : 2.1.3
1jtv_A_200 - HH => SUBCLASS : 2.1.12
1jtv_A_209 - HH => SUBCLASS : 3.7.5
1jtv_A_209 - HH => SUBCLASS : 3.7.6
1jtv_A_260 - HH => SUBCLASS : 4.33.1

Loops in ArchDB95 clusters

1jtv_A_30 - EH => SUBCLASS : 2.1.25
1jtv_A_59 - EH => SUBCLASS : 4.1.1
1jtv_A_3 - EH => SUBCLASS : 5.17.1
1jtv_A_86 - EH => SUBCLASS : 14.1.1
1jtv_A_200 - HH => SUBCLASS : 2.1.11
1jtv_A_200 - HH => SUBCLASS : 2.3.1
1jtv_A_209 - HH => SUBCLASS : 3.8.6
1jtv_A_260 - HH => SUBCLASS : 4.44.1
1jtv_A_153 - HE => SUBCLASS : 1.2.7
1jtv_A_233 - HE => SUBCLASS : 6.10.3

Loops in ArchDB-EC clusters

1jtv_A_209 - HH => SUBCLASS : 3.9.3

Loops not clustered in ArchDB

1jtv_A_135 - EH
1jtv_A_178 - EH
1jtv_A_252 - EH
1jtv_A_13 - HE
1jtv_A_43 - HE
1jtv_A_69 - HE
1jtv_A_116 - HE
1jtv_A_104 - HH

1a27 - - percentage of sequence identity: 100
1bhs - - percentage of sequence identity: 100
1dht A - percentage of sequence identity: 100
1equ A - percentage of sequence identity: 100
1equ B - percentage of sequence identity: 100
1fds - - percentage of sequence identity: 99
1fdt - - percentage of sequence identity: 99
1fdu A - percentage of sequence identity: 99
1fdu B - percentage of sequence identity: 99
1fdu C - percentage of sequence identity: 99
1fdu D - percentage of sequence identity: 99
1fdv A - percentage of sequence identity: 99
1fdv B - percentage of sequence identity: 99
1fdv C - percentage of sequence identity: 99
1fdv D - percentage of sequence identity: 99
1fdw - - percentage of sequence identity: 99
1i5r A - percentage of sequence identity: 100
1iol - - percentage of sequence identity: 99
1qyv A - percentage of sequence identity: 100
1qyw A - percentage of sequence identity: 100
1qyx A - percentage of sequence identity: 100
3dhe A - percentage of sequence identity: 100