PDB: 1k3t Compound: glyceraldehyde-3-phosphate dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2002-06-19 Resolution [Å]: 1.95 R-Factor: 0.201

CHAIN: A SWISS-PROT/TREMBL: P22513    KEYWORD: 3D-structure    Glycolysis    Glycosome    Multigene family    NAD    Oxidoreductase    EC: 1.2.1.12 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi GO:  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    glucose metabolism    glycolysis    CHAIN: B SWISS-PROT/TREMBL: P22513    KEYWORD: 3D-structure    Glycolysis    Glycosome    Multigene family    NAD    Oxidoreductase    EC: 1.2.1.12 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi GO:  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    glucose metabolism    glycolysis    CHAIN: C SWISS-PROT/TREMBL: P22513    KEYWORD: 3D-structure    Glycolysis    Glycosome    Multigene family    NAD    Oxidoreductase    EC: 1.2.1.12 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi GO:  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    glucose metabolism    glycolysis    CHAIN: D SWISS-PROT/TREMBL: P22513    KEYWORD: 3D-structure    Glycolysis    Glycosome    Multigene family    NAD    Oxidoreductase    EC: 1.2.1.12 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Trypanosoma cruzi GO:  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    glucose metabolism    glycolysis

Image Source: PDB

Loops in ArchDB95 clusters

1k3t_A_222 - EH => SUBCLASS : 0.1.46
1k3t_A_256 - EH => SUBCLASS : 5.10.1
1k3t_A_106 - EH => SUBCLASS : 7.10.1
1k3t_A_57 - AR => SUBCLASS : 2.1.6
1k3t_A_243 - AR => SUBCLASS : 5.79.1
1k3t_A_122 - HE => SUBCLASS : 3.1.1
1k3t_A_270 - HE => SUBCLASS : 6.11.1
1k3t_A_228 - HE => SUBCLASS : 7.10.1
1k3t_A_51 - HA => SUBCLASS : 3.3.2
1k3t_A_63 - HA => SUBCLASS : 6.4.1

Loops in ArchDB-EC clusters

1k3t_A_228 - HE => SUBCLASS : 7.6.1

Loops not clustered in ArchDB

1k3t_A_130 - AR
1k3t_A_243 - AR
1k3t_A_187 - AR
1k3t_A_130 - AR
1k3t_A_57 - AR
1k3t_A_187 - AR
1k3t_A_3 - EH
1k3t_A_31 - EH
1k3t_A_83 - EH
1k3t_A_326 - EH
1k3t_A_160 - EH
1k3t_A_308 - EH
1k3t_A_289 - HA
1k3t_A_63 - HA
1k3t_A_77 - HA
1k3t_A_142 - HA
1k3t_A_51 - HA
1k3t_A_289 - HA
1k3t_A_142 - HA
1k3t_A_77 - HA
1k3t_A_12 - HE
1k3t_A_312 - HE
1k3t_A_166 - HE
1k3t_A_99 - HE
1k3t_A_43 - HE
1k3t_A_117 - HH

1a7k A - percentage of sequence identity: 84
1a7k B - percentage of sequence identity: 84
1a7k C - percentage of sequence identity: 84
1a7k D - percentage of sequence identity: 84
1gga A - percentage of sequence identity: 90
1gga B - percentage of sequence identity: 90
1gga O - percentage of sequence identity: 90
1gga P - percentage of sequence identity: 90
1gga Q - percentage of sequence identity: 90
1gga R - percentage of sequence identity: 90
1gyp A - percentage of sequence identity: 84
1gyp B - percentage of sequence identity: 84
1gyp C - percentage of sequence identity: 84
1gyp D - percentage of sequence identity: 84
1gyq A - percentage of sequence identity: 84
1gyq B - percentage of sequence identity: 84
1gyq C - percentage of sequence identity: 84
1gyq D - percentage of sequence identity: 84
1i32 A - percentage of sequence identity: 84
1i32 B - percentage of sequence identity: 84
1i32 C - percentage of sequence identity: 84
1i32 D - percentage of sequence identity: 84
1i32 E - percentage of sequence identity: 84
1i32 F - percentage of sequence identity: 84
1i33 A - percentage of sequence identity: 84
1i33 B - percentage of sequence identity: 84
1i33 C - percentage of sequence identity: 84
1i33 D - percentage of sequence identity: 84
1i33 E - percentage of sequence identity: 84
1i33 F - percentage of sequence identity: 84
1k3t A - percentage of sequence identity: 100
1k3t B - percentage of sequence identity: 100
1k3t C - percentage of sequence identity: 100
1k3t D - percentage of sequence identity: 100
1ml3 A - percentage of sequence identity: 100
1ml3 B - percentage of sequence identity: 100
1ml3 C - percentage of sequence identity: 100
1ml3 D - percentage of sequence identity: 100
1qxs A - percentage of sequence identity: 100
1qxs B - percentage of sequence identity: 100
1qxs C - percentage of sequence identity: 100
1qxs D - percentage of sequence identity: 100