PDB: 1n46 Compound: thyroid hormone receptor beta-1 Classification: TRANSCRIPTION Entry date in PDB: 2003-04-22 Resolution [Å]: 2.20 R-Factor: 0.195

CHAIN: A SWISS-PROT/TREMBL: P10828    KEYWORD: 3D-structure    Alternative splicing    Deafness    Disease mutation    DNA-binding    Multigene family    Nuclear protein    Polymorphism    Receptor    Transcription regulation    Zinc-finger    SCOP: a.123.1.1 All alpha proteins    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Thyroid hormone receptor beta (TR-beta)    Human (Homo sapiens) GO:  nucleus    DNA binding    ligand-dependent nuclear receptor activity    steroid hormone receptor activity    thyroid hormone receptor activity    transcription factor activity    regulation of transcription, DNA-dependent    CHAIN: B SWISS-PROT/TREMBL: P10828    KEYWORD: 3D-structure    Alternative splicing    Deafness    Disease mutation    DNA-binding    Multigene family    Nuclear protein    Polymorphism    Receptor    Transcription regulation    Zinc-finger    SCOP: a.123.1.1 All alpha proteins    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Thyroid hormone receptor beta (TR-beta)    Human (Homo sapiens) GO:  nucleus    DNA binding    ligand-dependent nuclear receptor activity    steroid hormone receptor activity    thyroid hormone receptor activity    transcription factor activity    regulation of transcription, DNA-dependent

Image Source: PDB

Loops in ArchDB40 clusters

1n46_A_328 - HA => SUBCLASS : 3.5.1
1n46_A_349 - HH => SUBCLASS : 3.2.13
1n46_A_338 - HH => SUBCLASS : 3.18.1

Loops in ArchDB95 clusters

1n46_A_349 - HH => SUBCLASS : 3.17.1
1n46_A_338 - HH => SUBCLASS : 3.27.1
1n46_A_389 - HH => SUBCLASS : 6.48.1
1n46_A_367 - HH => SUBCLASS : 7.17.1
1n46_A_328 - HA => SUBCLASS : 3.7.1

Loops not clustered in ArchDB

1n46_A_244 - EH
1n46_A_334 - EH
1n46_A_216 - HE
1n46_A_298 - HE
1n46_A_266 - HH
1n46_A_276 - HH
1n46_A_417 - HH

1bsx A - percentage of sequence identity: 100
1bsx B - percentage of sequence identity: 100
1n46 A - percentage of sequence identity: 100
1n46 B - percentage of sequence identity: 100
1nav A - percentage of sequence identity: 83
1nax A - percentage of sequence identity: 100
1nq0 A - percentage of sequence identity: 99
1nq1 A - percentage of sequence identity: 99
1nq2 A - percentage of sequence identity: 99
1nuo A - percentage of sequence identity: 99
1q4x A - percentage of sequence identity: 100
1r6g A - percentage of sequence identity: 99
1xzx X - percentage of sequence identity: 100
1y0x X - percentage of sequence identity: 100