PDB: 1nbu Compound: probable dihydroneopterin aldolase Classification: LYASE Entry date in PDB: 2004-01-13 Resolution [Å]: 1.60 R-Factor: 0.177

CHAIN: A SWISS-PROT/TREMBL: O06275    KEYWORD: Complete proteome    Folate biosynthesis    Lyase    EC: 4.1.2.25 SCOP: d.96.1.3 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    DHN aldolase/epimerase    7,8-dihydroneopterin aldolase    Bacteria (Mycobacterium tuberculosis) GO:  dihydroneopterin aldolase activity    folic acid and derivative metabolism    CHAIN: B SWISS-PROT/TREMBL: O06275    KEYWORD: Complete proteome    Folate biosynthesis    Lyase    EC: 4.1.2.25 SCOP: d.96.1.3 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    DHN aldolase/epimerase    7,8-dihydroneopterin aldolase    Bacteria (Mycobacterium tuberculosis) GO:  dihydroneopterin aldolase activity    folic acid and derivative metabolism    CHAIN: C SWISS-PROT/TREMBL: O06275    KEYWORD: Complete proteome    Folate biosynthesis    Lyase    EC: 4.1.2.25 SCOP: d.96.1.3 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    DHN aldolase/epimerase    7,8-dihydroneopterin aldolase    Bacteria (Mycobacterium tuberculosis) GO:  dihydroneopterin aldolase activity    folic acid and derivative metabolism    CHAIN: D SWISS-PROT/TREMBL: O06275    KEYWORD: Complete proteome    Folate biosynthesis    Lyase    EC: 4.1.2.25 SCOP: d.96.1.3 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    DHN aldolase/epimerase    7,8-dihydroneopterin aldolase    Bacteria (Mycobacterium tuberculosis) GO:  dihydroneopterin aldolase activity    folic acid and derivative metabolism    CHAIN: E SWISS-PROT/TREMBL: O06275    KEYWORD: Complete proteome    Folate biosynthesis    Lyase    EC: 4.1.2.25 SCOP: d.96.1.3 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    DHN aldolase/epimerase    7,8-dihydroneopterin aldolase    Bacteria (Mycobacterium tuberculosis) GO:  dihydroneopterin aldolase activity    folic acid and derivative metabolism    CHAIN: F SWISS-PROT/TREMBL: O06275    KEYWORD: Complete proteome    Folate biosynthesis    Lyase    EC: 4.1.2.25 SCOP: d.96.1.3 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    DHN aldolase/epimerase    7,8-dihydroneopterin aldolase    Bacteria (Mycobacterium tuberculosis) GO:  dihydroneopterin aldolase activity    folic acid and derivative metabolism    CHAIN: G SWISS-PROT/TREMBL: O06275    KEYWORD: Complete proteome    Folate biosynthesis    Lyase    EC: 4.1.2.25 SCOP: d.96.1.3 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    DHN aldolase/epimerase    7,8-dihydroneopterin aldolase    Bacteria (Mycobacterium tuberculosis) GO:  dihydroneopterin aldolase activity    folic acid and derivative metabolism    CHAIN: H SWISS-PROT/TREMBL: O06275    KEYWORD: Complete proteome    Folate biosynthesis    Lyase    EC: 4.1.2.25 SCOP: d.96.1.3 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    DHN aldolase/epimerase    7,8-dihydroneopterin aldolase    Bacteria (Mycobacterium tuberculosis) GO:  dihydroneopterin aldolase activity    folic acid and derivative metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1nbu_A_27 - EH => SUBCLASS : 1.1.45
1nbu_A_40 - HH => SUBCLASS : 8.8.1

Loops in ArchDB95 clusters

1nbu_A_27 - EH => SUBCLASS : 2.2.17
1nbu_A_40 - HH => SUBCLASS : 8.15.1
1nbu_A_73 - HE => SUBCLASS : 5.2.1

Loops not clustered in ArchDB

1nbu_A_4 - EH
1nbu_A_92 - HA
1nbu_A_22 - HE
1nbu_A_54 - HH

1nbu A - percentage of sequence identity: 100
1nbu B - percentage of sequence identity: 99
1nbu C - percentage of sequence identity: 98
1nbu D - percentage of sequence identity: 99
1nbu E - percentage of sequence identity: 100
1nbu F - percentage of sequence identity: 100
1nbu G - percentage of sequence identity: 100
1nbu H - percentage of sequence identity: 100
1z9w A - percentage of sequence identity: 100