PDB: 1p57 Compound: serine protease hepsin Classification: HYDROLASE Entry date in PDB: 2004-01-20 Resolution [Å]: 1.75 R-Factor: 0.186

CHAIN: A SWISS-PROT/TREMBL: P05981    KEYWORD: Hydrolase    Serine protease    Signal-anchor    Transmembrane    EC: 3.4.21.- SCOP: d.170.1.2 Alpha and beta proteins (a+b)    SRCR-like    SRCR-like    Hepsin, N-terminal domain    Hepsin, N-terminal domain    Human (Homo sapiens) GO:  membrane    chymotrypsin activity    scavenger receptor activity    trypsin activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P05981    KEYWORD: Hydrolase    Serine protease    Signal-anchor    Transmembrane    EC: 3.4.21.- SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Hepsin, catalytic domain    Human (Homo sapiens) GO:  membrane    chymotrypsin activity    scavenger receptor activity    trypsin activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1p57_B_30 - HA => SUBCLASS : 2.4.1
1p57_A_9 - HA => SUBCLASS : 4.1.1
1p57_A_18 - HA => SUBCLASS : 4.1.1
1p57_B_39 - HA => SUBCLASS : 4.3.2
1p57_A_9 - HA => SUBCLASS : 6.1.1
1p57_B_226 - EH => SUBCLASS : 0.1.4
1p57_B_156 - EH => SUBCLASS : 1.1.14
1p57_A_27 - EH => SUBCLASS : 3.8.1
1p57_B_20 - AR => SUBCLASS : 8.4.1
1p57_B_180 - AR => SUBCLASS : 16.2.1
1p57_B_104 - AR => SUBCLASS : 26.1.1

Loops in ArchDB95 clusters

1p57_B_226 - EH => SUBCLASS : 0.1.2
1p57_B_156 - EH => SUBCLASS : 1.1.8
1p57_A_27 - EH => SUBCLASS : 3.8.6
1p57_B_20 - AR => SUBCLASS : 8.3.1
1p57_B_180 - AR => SUBCLASS : 16.1.1
1p57_B_104 - AR => SUBCLASS : 26.1.1
1p57_B_30 - HA => SUBCLASS : 2.1.2
1p57_A_9 - HA => SUBCLASS : 4.1.1
1p57_A_18 - HA => SUBCLASS : 4.1.1
1p57_B_39 - HA => SUBCLASS : 4.2.1
1p57_B_135 - HA => SUBCLASS : 14.4.1

Loops not clustered in ArchDB

1p57_B_51 - AR
1p57_B_81 - AR
1p57_A_90 - AR
1p57_A_53 - EH
1p57_A_72 - HA
1p57_B_208 - HA
1p57_B_198 - HA
1p57_B_85 - HA
1p57_B_65 - HA
1p57_B_165 - HE
1p57_B_235 - HE
1p57_A_37 - HE
1p57_A_61 - HE

1o5e H - percentage of sequence identity: 100
1o5f H - percentage of sequence identity: 100
1z8g A - percentage of sequence identity: 100
null nu - percentage of sequence identity: 0