PDB: 1pme Compound: erk2 Classification: TRANSFERASE Entry date in PDB: 1999-06-08 Resolution [Å]: 2.00 R-Factor: 0.212

CHAIN: - SWISS-PROT/TREMBL: P28482    KEYWORD: 3D-structure    ATP-binding    Cell cycle    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.37 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    MAP kinase Erk2    Human (Homo sapiens) GO:  ATP binding    MAP kinase activity    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation

Image Source: PDB

Loops in ArchDB-EC clusters

1pme_*_284 - HH => SUBCLASS : 9.1.1

Loops in ArchDB-KI clusters

1pme_*_163 - AR => SUBCLASS : 5.1.1
1pme_*_145 - AR => SUBCLASS : 8.1.1
1pme_*_50 - EH => SUBCLASS : 4.2.1
1pme_*_39 - HA => SUBCLASS : 4.1.1
1pme_*_123 - HE => SUBCLASS : 1.1.3
1pme_*_62 - HE => SUBCLASS : 10.2.1
1pme_*_112 - HH => SUBCLASS : 4.4.1
1pme_*_258 - HH => SUBCLASS : 8.1.1
1pme_*_284 - HH => SUBCLASS : 9.1.1
1pme_*_208 - HH => SUBCLASS : 9.2.1

Loops not clustered in ArchDB

1pme_*_163 - AR
1pme_*_145 - AR
1pme_*_101 - AR
1pme_*_50 - EH
1pme_*_110 - EH
1pme_*_172 - EH
1pme_*_155 - HA
1pme_*_88 - HA
1pme_*_39 - HA
1pme_*_25 - HA
1pme_*_123 - HE
1pme_*_62 - HE
1pme_*_304 - HH
1pme_*_275 - HH
1pme_*_249 - HH
1pme_*_233 - HH
1pme_*_208 - HH
1pme_*_112 - HH
1pme_*_258 - HH

Loops not clustered in ArchDB-KI

1pme_*_101 - AR
1pme_*_110 - EH
1pme_*_172 - EH
1pme_*_88 - HA
1pme_*_155 - HA
1pme_*_25 - HA
1pme_*_275 - HH
1pme_*_233 - HH
1pme_*_304 - HH
1pme_*_249 - HH

1erk - - percentage of sequence identity: 91
1gol - - percentage of sequence identity: 91
1tvo A - percentage of sequence identity: 98
1wzy A - percentage of sequence identity: 98
2erk - - percentage of sequence identity: 98
3erk - - percentage of sequence identity: 91
4erk - - percentage of sequence identity: 91