PDB: 1pvd Compound: Pyruvate decarboxylase (pdc) Classification: LYASE (CARBON-CARBON) Entry date in PDB: 1995-07-31 Resolution [Å]: 2.30 R-Factor: 0.165

CHAIN: A SWISS-PROT/TREMBL: P06169    KEYWORD: 3D-structure    Acetylation    Decarboxylase    Flavoprotein    Lyase    Magnesium    Metal-binding    Multigene family    Thiamine pyrophosphate    EC: 4.1.1.1 SCOP: c.31.1.3 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Pyruvate oxidase and decarboxylase, middle domain    Pyruvate decarboxylase    Baker's yeast (Saccharomyces cerevisiae) SCOP: c.36.1.5 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase Pyr module    Pyruvate decarboxylase    Baker's yeast (Saccharomyces cerevisiae) SCOP: c.36.1.9 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase PP module    Pyruvate decarboxylase    Baker's yeast (Saccharomyces cerevisiae) GO:  catalytic activity    thiamin pyrophosphate binding    CHAIN: B SWISS-PROT/TREMBL: P06169    KEYWORD: 3D-structure    Acetylation    Decarboxylase    Flavoprotein    Lyase    Magnesium    Metal-binding    Multigene family    Thiamine pyrophosphate    EC: 4.1.1.1 SCOP: c.31.1.3 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Pyruvate oxidase and decarboxylase, middle domain    Pyruvate decarboxylase    Baker's yeast (Saccharomyces cerevisiae) SCOP: c.36.1.5 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase Pyr module    Pyruvate decarboxylase    Baker's yeast (Saccharomyces cerevisiae) SCOP: c.36.1.9 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase PP module    Pyruvate decarboxylase    Baker's yeast (Saccharomyces cerevisiae) GO:  catalytic activity    thiamin pyrophosphate binding

Image Source: PDB

Loops in ArchDB40 clusters

1pvd_A_305 - HA => SUBCLASS : 2.2.1
1pvd_A_313 - HA => SUBCLASS : 2.3.1
1pvd_A_68 - EH => SUBCLASS : 1.7.1
1pvd_A_507 - EH => SUBCLASS : 2.1.1
1pvd_A_507 - EH => SUBCLASS : 2.4.1
1pvd_A_135 - EH => SUBCLASS : 3.7.5
1pvd_A_135 - EH => SUBCLASS : 3.12.1
1pvd_A_383 - EH => SUBCLASS : 3.14.1
1pvd_A_319 - EH => SUBCLASS : 4.20.1
1pvd_A_259 - EH => SUBCLASS : 5.2.3

Loops in ArchDB95 clusters

1pvd_A_507 - EH => SUBCLASS : 2.1.10
1pvd_A_507 - EH => SUBCLASS : 2.3.1
1pvd_A_68 - EH => SUBCLASS : 2.16.1
1pvd_A_135 - EH => SUBCLASS : 3.3.4
1pvd_A_135 - EH => SUBCLASS : 3.10.1
1pvd_A_383 - EH => SUBCLASS : 3.12.3
1pvd_A_383 - EH => SUBCLASS : 3.12.5
1pvd_A_383 - EH => SUBCLASS : 3.36.1
1pvd_A_319 - EH => SUBCLASS : 4.23.1
1pvd_A_465 - EH => SUBCLASS : 4.75.1
1pvd_A_259 - EH => SUBCLASS : 5.2.3
1pvd_A_214 - EH => SUBCLASS : 7.28.1
1pvd_A_145 - HE => SUBCLASS : 2.1.1
1pvd_A_76 - HE => SUBCLASS : 2.1.1
1pvd_A_228 - HE => SUBCLASS : 2.1.2
1pvd_A_194 - HE => SUBCLASS : 2.2.1
1pvd_A_270 - HE => SUBCLASS : 2.2.3
1pvd_A_194 - HE => SUBCLASS : 2.2.6
1pvd_A_124 - HE => SUBCLASS : 2.2.7
1pvd_A_124 - HE => SUBCLASS : 2.3.4
1pvd_A_228 - HE => SUBCLASS : 3.2.1
1pvd_A_6 - HE => SUBCLASS : 3.3.1
1pvd_A_417 - HE => SUBCLASS : 5.6.2
1pvd_A_454 - HE => SUBCLASS : 5.35.1
1pvd_A_305 - HA => SUBCLASS : 2.2.1
1pvd_A_313 - HA => SUBCLASS : 2.3.1

Loops in ArchDB-EC clusters

1pvd_A_498 - HE => SUBCLASS : 4.3.4

Loops not clustered in ArchDB

1pvd_A_163 - AR
1pvd_A_163 - AR
1pvd_A_533 - EH
1pvd_A_438 - EH
1pvd_A_405 - EH
1pvd_A_175 - EH
1pvd_A_21 - EH
1pvd_A_3 - EH
1pvd_A_44 - EH
1pvd_A_95 - EH
1pvd_A_305 - HA
1pvd_A_281 - HA
1pvd_A_281 - HA
1pvd_A_242 - HA
1pvd_A_242 - HA
1pvd_A_313 - HA
1pvd_A_390 - HE
1pvd_A_367 - HE
1pvd_A_51 - HE
1pvd_A_31 - HE
1pvd_A_515 - HE
1pvd_A_475 - HH
1pvd_A_444 - HH
1pvd_A_326 - HH

1pvd A - percentage of sequence identity: 100
1pvd B - percentage of sequence identity: 100
1pyd A - percentage of sequence identity: 100
1pyd B - percentage of sequence identity: 100
1qpb A - percentage of sequence identity: 98
1qpb B - percentage of sequence identity: 98