PDB: 1r7i Compound: 3-hydroxy-3-methylglutaryl-coenzyme a reductase Classification: OXIDOREDUCTASE Entry date in PDB: 2003-11-11 Resolution [Å]: 2.21 R-Factor: 0.256

CHAIN: A SWISS-PROT/TREMBL: P13702    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.1.1.88 SCOP: d.58.20.1 Alpha and beta proteins (a+b)    Ferredoxin-like    NAD-binding domain of HMG-CoA reductase    NAD-binding domain of HMG-CoA reductase    NAD-binding domain of HMG-CoA reductase    Pseudomonas mevalonii SCOP: d.179.1.1 Alpha and beta proteins (a+b)    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Pseudomonas mevalonii SCOP: d.179.1.1 Alpha and beta proteins (a+b)    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Pseudomonas mevalonii GO:  hydroxymethylglutaryl-CoA reductase (NADPH) activity    hydroxymethylglutaryl-CoA reductase activity    biosynthesis    lipid metabolism    CHAIN: B SWISS-PROT/TREMBL: P13702    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.1.1.88 SCOP: d.58.20.1 Alpha and beta proteins (a+b)    Ferredoxin-like    NAD-binding domain of HMG-CoA reductase    NAD-binding domain of HMG-CoA reductase    NAD-binding domain of HMG-CoA reductase    Pseudomonas mevalonii SCOP: d.179.1.1 Alpha and beta proteins (a+b)    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Pseudomonas mevalonii SCOP: d.179.1.1 Alpha and beta proteins (a+b)    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Substrate-binding domain of HMG-CoA reductase    Pseudomonas mevalonii GO:  hydroxymethylglutaryl-CoA reductase (NADPH) activity    hydroxymethylglutaryl-CoA reductase activity    biosynthesis    lipid metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1r7i_A_305 - HA => SUBCLASS : 3.1.1
1r7i_A_77 - EH => SUBCLASS : 4.33.2
1r7i_A_62 - AR => SUBCLASS : 2.2.4
1r7i_A_241 - HH => SUBCLASS : 1.2.1
1r7i_A_241 - HH => SUBCLASS : 1.2.2
1r7i_A_135 - HH => SUBCLASS : 1.2.6
1r7i_A_15 - HH => SUBCLASS : 3.2.2
1r7i_A_15 - HH => SUBCLASS : 3.3.1
1r7i_A_336 - HH => SUBCLASS : 4.2.1

Loops in ArchDB95 clusters

1r7i_A_62 - AR => SUBCLASS : 2.5.3
1r7i_A_62 - AR => SUBCLASS : 2.5.4
1r7i_A_104 - AR => SUBCLASS : 2.9.5
1r7i_A_241 - HH => SUBCLASS : 1.1.1
1r7i_A_241 - HH => SUBCLASS : 1.1.8
1r7i_A_241 - HH => SUBCLASS : 1.2.1
1r7i_A_135 - HH => SUBCLASS : 1.2.3
1r7i_A_15 - HH => SUBCLASS : 3.1.2
1r7i_A_259 - HH => SUBCLASS : 3.2.6
1r7i_A_336 - HH => SUBCLASS : 4.8.1
1r7i_A_305 - HA => SUBCLASS : 3.1.1

Loops not clustered in ArchDB

1r7i_A_73 - AR
1r7i_A_208 - AR
1r7i_A_172 - EH
1r7i_A_315 - EH
1r7i_A_111 - EH
1r7i_A_222 - EH
1r7i_A_69 - HA
1r7i_A_155 - HA
1r7i_A_284 - HE
1r7i_A_187 - HE
1r7i_A_147 - HE
1r7i_A_86 - HE
1r7i_A_44 - HE
1r7i_A_30 - HH
1r7i_A_124 - HH
1r7i_A_231 - HH
1r7i_A_331 - HH

1qax A - percentage of sequence identity: 100
1qax B - percentage of sequence identity: 100
1qay A - percentage of sequence identity: 100
1qay B - percentage of sequence identity: 100
1r31 A - percentage of sequence identity: 100
1r31 B - percentage of sequence identity: 100
1r7i A - percentage of sequence identity: 100
1r7i B - percentage of sequence identity: 100
1t02 A - percentage of sequence identity: 100
1t02 B - percentage of sequence identity: 100