PDB: 1s14 Compound: topoisomerase iv subunit b Classification: ISOMERASE Entry date in PDB: 2004-05-04 Resolution [Å]: 2.00 R-Factor: 0.219

CHAIN: A SWISS-PROT/TREMBL: P20083    KEYWORD: Antibiotic resistance    ATP-binding    Complete proteome    Isomerase    Topoisomerase    EC: 5.99.1.- SCOP: d.122.1.2 Alpha and beta proteins (a+b)    ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase    ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase    DNA gyrase/MutL, N-terminal domain    Topoisomerase IV subunit B    Escherichia coli GO:  chromosome    ATP binding    DNA binding    DNA topoisomerase (ATP-hydrolyzing) activity    DNA metabolism    DNA topological change    DNA unwinding    CHAIN: B SWISS-PROT/TREMBL: P20083    KEYWORD: Antibiotic resistance    ATP-binding    Complete proteome    Isomerase    Topoisomerase    EC: 5.99.1.- SCOP: d.122.1.2 Alpha and beta proteins (a+b)    ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase    ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase    DNA gyrase/MutL, N-terminal domain    Topoisomerase IV subunit B    Escherichia coli GO:  chromosome    ATP binding    DNA binding    DNA topoisomerase (ATP-hydrolyzing) activity    DNA metabolism    DNA topological change    DNA unwinding

Image Source: PDB

Loops in ArchDB40 clusters

1s14_A_1033 - HE => SUBCLASS : 4.2.1
1s14_A_1033 - HE => SUBCLASS : 4.2.2
1s14_A_1181 - HE => SUBCLASS : 4.25.1
1s14_A_1054 - HA => SUBCLASS : 3.1.1
1s14_A_1199 - HA => SUBCLASS : 4.1.1
1s14_A_1145 - AR => SUBCLASS : 4.3.6
1s14_A_1086 - HH => SUBCLASS : 1.1.13
1s14_A_1086 - HH => SUBCLASS : 1.1.17

Loops in ArchDB95 clusters

1s14_A_1145 - AR => SUBCLASS : 4.6.4
1s14_A_1086 - HH => SUBCLASS : 1.1.6
1s14_A_1086 - HH => SUBCLASS : 1.1.14
1s14_A_1033 - HE => SUBCLASS : 4.2.1
1s14_A_1181 - HE => SUBCLASS : 4.20.1
1s14_A_1054 - HA => SUBCLASS : 3.1.1
1s14_A_1199 - HA => SUBCLASS : 4.1.1

Loops not clustered in ArchDB

1s14_A_1065 - EH
1s14_A_1162 - EH
1s14_A_1122 - HA
1s14_A_1135 - HA
1s14_A_1118 - HE

1s14 A - percentage of sequence identity: 100
1s14 B - percentage of sequence identity: 100
1s16 A - percentage of sequence identity: 89
1s16 B - percentage of sequence identity: 89