PDB: 1t2v Compound: breast cancer type 1 susceptibility protein Classification: ANTITUMOR PROTEIN Entry date in PDB: 2004-05-11 Resolution [Å]: 3.30 R-Factor: 0.261

CHAIN: A SWISS-PROT/TREMBL: P38398    KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger    SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination    CHAIN: B SWISS-PROT/TREMBL: P38398    KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger    SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination    CHAIN: C SWISS-PROT/TREMBL: P38398    KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger    SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination    CHAIN: D SWISS-PROT/TREMBL: P38398    KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger    SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination    CHAIN: E SWISS-PROT/TREMBL: P38398    KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger    SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens) GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination

Image Source: PDB

1l0b A - percentage of sequence identity: 65
1t15 A - percentage of sequence identity: 100