PDB: 1zfj Compound: inosine monophosphate dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2000-03-29 Resolution [Å]: 1.90 R-Factor: 0.232

CHAIN: A SWISS-PROT/TREMBL: P50099    KEYWORD: 3D-structure    CBS domain    Complete proteome    GMP biosynthesis    NAD    Oxidoreductase    Purine biosynthesis    Repeat    EC: 1.1.1.205 SCOP: c.1.5.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Inosine monophosphate dehydrogenase (IMPDH)    Inosine monophosphate dehydrogenase (IMPDH)    Inosine monophosphate dehydrogenase (IMPDH)    Streptococcus pyogenes SCOP: c.1.5.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Inosine monophosphate dehydrogenase (IMPDH)    Inosine monophosphate dehydrogenase (IMPDH)    Inosine monophosphate dehydrogenase (IMPDH)    Streptococcus pyogenes SCOP: d.37.1.1 Alpha and beta proteins (a+b)    CBS-domain    CBS-domain    CBS-domain    Type II inosine monophosphate dehydrogenase CBS domains    Streptococcus pyogenes SCOP: d.37.1.1 Alpha and beta proteins (a+b)    CBS-domain    CBS-domain    CBS-domain    Type II inosine monophosphate dehydrogenase CBS domains    Streptococcus pyogenes GO:  catalytic activity    IMP dehydrogenase activity    nicotinate-nucleotide diphosphorylase (carboxylating) activity    GMP biosynthesis    NAD biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

1zfj_A_379 - HA => SUBCLASS : 2.1.1
1zfj_A_36 - HA => SUBCLASS : 2.2.1
1zfj_A_187 - HA => SUBCLASS : 3.1.1
1zfj_A_167 - EH => SUBCLASS : 3.4.5
1zfj_A_167 - EH => SUBCLASS : 4.23.2
1zfj_A_339 - EH => SUBCLASS : 5.39.1

Loops in ArchDB95 clusters

1zfj_A_226 - EH => SUBCLASS : 2.4.2
1zfj_A_167 - EH => SUBCLASS : 3.6.6
1zfj_A_339 - EH => SUBCLASS : 5.12.1
1zfj_A_42 - AR => SUBCLASS : 3.4.1
1zfj_A_379 - HA => SUBCLASS : 2.1.1
1zfj_A_36 - HA => SUBCLASS : 2.2.1
1zfj_A_187 - HA => SUBCLASS : 3.1.1

Loops in ArchDB-EC clusters

1zfj_A_260 - HE => SUBCLASS : 4.1.1

Loops not clustered in ArchDB

1zfj_A_19 - AR
1zfj_A_136 - AR
1zfj_A_19 - AR
1zfj_A_42 - AR
1zfj_A_136 - AR
1zfj_A_49 - EH
1zfj_A_465 - EH
1zfj_A_424 - EH
1zfj_A_299 - EH
1zfj_A_278 - EH
1zfj_A_71 - EH
1zfj_A_249 - EH
1zfj_A_197 - EH
1zfj_A_124 - HA
1zfj_A_385 - HA
1zfj_A_36 - HA
1zfj_A_124 - HA
1zfj_A_379 - HA
1zfj_A_187 - HA
1zfj_A_385 - HA
1zfj_A_456 - HE
1zfj_A_63 - HE
1zfj_A_110 - HE
1zfj_A_173 - HE
1zfj_A_203 - HE
1zfj_A_235 - HE
1zfj_A_286 - HE
1zfj_A_322 - HE
1zfj_A_349 - HE
1zfj_A_80 - HH
1zfj_A_312 - HH
1zfj_A_442 - HH
1zfj_A_433 - HH

1eep B - percentage of sequence identity: 62