Logo
Information on 2dhf
PDB: 2dhf
Compound: Dihydrofolate reductase (DHFR) complex with 5-deaz
Classification: OXIDO-REDUCTASE
Entry date in PDB: 1990-07-15
Resolution [Å]: 2.30
R-Factor: 0.194


CHAIN: A
SWISS-PROT/TREMBL: P00374
   KEYWORD: 3D-structure    NADP    One-carbon metabolism    Oxidoreductase   
EC: 1.5.1.3
SCOP: c.71.1.1 Alpha and beta proteins (a/b)    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases, eukaryotic type    Human (Homo sapiens)
GO:  dihydrofolate reductase activity    glycine biosynthesis    nucleotide biosynthesis   


CHAIN: B
SWISS-PROT/TREMBL: P00374
   KEYWORD: 3D-structure    NADP    One-carbon metabolism    Oxidoreductase   
EC: 1.5.1.3
SCOP: c.71.1.1 Alpha and beta proteins (a/b)    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases, eukaryotic type    Human (Homo sapiens)
GO:  dihydrofolate reductase activity    glycine biosynthesis    nucleotide biosynthesis   
2dhf Image
Image Source: PDB
Homologous structures to 2dhf classified in ArchDB

1kmv A - percentage of sequence identity: 100
8dfr - - percentage of sequence identity: 75