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Information on SUBCLASS 4.25.1
Subclass Accession number: 3119
Subclass: 4.25.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 13

Average sequence ID (%) : 46.7 +/- 27.9
Average RMSD (Å) : 0.300 +/- 0.071

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: YhXhpGXh
(φψ)-conformation: bppbaeaa
Pattern: [iktv][ilv]x[y][fw][dknp][ailmv][kmr][g]x[acmv][ehq]x[cilmt][r][flmwy][ilv][fl][ae]x
Conservation:-0.7450.252-1.3272.4451.079-0.552-0.4900.0671.933-0.398-0.552-0.324-1.116-0.6701.420-0.4200.2410.128-0.179-0.794
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1aqw_A_31aqw   A423TVVYFPVRGRCAALRMLLADEEEE-SS-GGGHHHHHHHHHbbbbxxbaeaaaaaaaaaaa
1dug_A_31dug   A322ILGYWKIKGLVQPTRLLLEYEEEEESSSGGGHHHHHHHHHbbbbxxbaeaaaaaaaaaaa
1ev9_A_61ev9   A625VLHYFNARGRMECIRFLLAAEEEEESS-TTTHHHHHHHHHbbbbxxbaeaaaaaaaaaaa
1gne_*_31gne   -322ILGYWKIKGLVQPTRLLLEYEEEEESSSTTTHHHHHHHHHbbxbxxbaeaaaaaaaaaaa
1gsu_A_21gsu   A322TLGYWDIRGLAHAIRLLLEYEEEEESSSGGGHHHHHHHHHbbbbxxbaeaaaaaaaaaaa
1hna_*_21hna   -322TLGYWNIRGLAHSIRLLLEYEEEEESSSGGGHHHHHHHHHbbbbxxbaeaaaaaaaaaaa
1iyh_A_41iyh   A524KLTYFNMRGRAEIIRYIFAYEEEEESSSGGGHHHHHHHHHbxbbxxbaeaaaaaaaaaaa
1k3y_A_61k3y   A625KLHYFNARGRMESTRWLLAAEEEEESSSTTTHHHHHHHHHbxbbxxbaeaaaaaaaaaaa
1ml6_A_51ml6   A524VLHYFNARGRMECIRWLLAAEEEEESS-GGGHHHHHHHHHbbbbxxbaeaaaaaaaaaaa
1okt_A_51okt   A625VLYYFDARGKAELIRLIFAYEEEEESSSTTTHHHHHHHHHbbbbxxbaeaaaaaaaaaaa
1pd2_1_41pd2   1524KLLYFNMRGRAEIIRYIFAYEEEEESSSTTTHHHHHHHHHbxbbxxbaeaaaaaaaaaaa
2gsq_*_32gsq   -423TLHYFPLMGRAELCRFVLAAEEEE-SSSGGGHHHHHHHHHbbbbxxbaeaaaaaaaaaaa
2gsr_A_32gsr   A423TITYFPVRGRCEAMRMLLADEEEE-SSSTTTHHHHHHHHHbbbbxwbaeaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1aqw_A_31aqw   A     ILGGLUTAMYL GROUP R - 13
1aqw_A_31aqw   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID L - 21
1aqw_A_31aqw   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID A - 22
1aqw_A_31aqw   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID D - 23
1dug_A_31dug   A     GSHGLUTHATHIONE Y - 6
1dug_A_31dug   A     GSHGLUTHATHIONE W - 7
1dug_A_31dug   A     GSHGLUTHATHIONE L - 12
1ev9_A_61ev9   A     GTSGLUTATHIONE SULFONIC ACID Y - 9
1ev9_A_61ev9   A     GTSGLUTATHIONE SULFONIC ACID F - 10
1ev9_A_61ev9   A     GTSGLUTATHIONE SULFONIC ACID G - 14
1ev9_A_61ev9   A     GTSGLUTATHIONE SULFONIC ACID R - 15
1gne_*_31gne   *     GSHGLUTHATHIONE I - 9
1gsu_A_21gsu   A     GTXS-HEXYLGLUTATHIONE Y - 6
1gsu_A_21gsu   A     GTXS-HEXYLGLUTATHIONE W - 7
1gsu_A_21gsu   A     GTXS-HEXYLGLUTATHIONE I - 9
1gsu_A_21gsu   A     GTXS-HEXYLGLUTATHIONE R - 10
1gsu_A_21gsu   A     GTXS-HEXYLGLUTATHIONE G - 11
1gsu_A_21gsu   A     GTXS-HEXYLGLUTATHIONE L - 12
1hna_*_21hna   *     GDNGLUTATHIONE S-(2,4 DINITROBENZENE) Y - 6
1hna_*_21hna   *     GDNGLUTATHIONE S-(2,4 DINITROBENZENE) W - 7
1hna_*_21hna   *     GDNGLUTATHIONE S-(2,4 DINITROBENZENE) L - 12
1iyh_A_41iyh   A     GSHGLUTHATHIONE Y - 8
1iyh_A_41iyh   A     GSHGLUTHATHIONE F - 9
1iyh_A_41iyh   A     GSHGLUTHATHIONE G - 13
1iyh_A_41iyh   A     GSHGLUTHATHIONE R - 14
1k3y_A_61k3y   A     GTXS-HEXYLGLUTATHIONE Y - 9
1k3y_A_61k3y   A     GTXS-HEXYLGLUTATHIONE F - 10
1k3y_A_61k3y   A     GTXS-HEXYLGLUTATHIONE G - 14
1k3y_A_61k3y   A     GTXS-HEXYLGLUTATHIONE R - 15
1k3y_A_61k3y   A     GOLGLYCEROL R - 15
1k3y_A_61k3y   A     GOLGLYCEROL S - 18
1ml6_A_51ml6   A     GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID Y - 8
1ml6_A_51ml6   A     GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID F - 9
1ml6_A_51ml6   A     GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID N - 10
1ml6_A_51ml6   A     GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID A - 11
1ml6_A_51ml6   A     GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID G - 13
1ml6_A_51ml6   A     GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID R - 14
1okt_A_51okt   A     FMTFORMIC ACID F - 10
1okt_A_51okt   A     FMTFORMIC ACID K - 15
1pd2_1_41pd2   1     GTTGLUTATHIONE Y - 8
1pd2_1_41pd2   1     GTTGLUTATHIONE F - 9
1pd2_1_41pd2   1     GTTGLUTATHIONE M - 11
1pd2_1_41pd2   1     GTTGLUTATHIONE G - 13
1pd2_1_41pd2   1     GTTGLUTATHIONE R - 14
2gsq_*_32gsq   *     GBIS-(3-IODOBENZYL)GLUTATHIONE Y - 7
2gsq_*_32gsq   *     GBIS-(3-IODOBENZYL)GLUTATHIONE F - 8
2gsq_*_32gsq   *     GBIS-(3-IODOBENZYL)GLUTATHIONE L - 10
2gsq_*_32gsq   *     GBIS-(3-IODOBENZYL)GLUTATHIONE M - 11
2gsq_*_32gsq   *     GBIS-(3-IODOBENZYL)GLUTATHIONE G - 12
2gsq_*_32gsq   *     GBIS-(3-IODOBENZYL)GLUTATHIONE R - 13
2gsr_A_32gsr   A     OCSCYSTEINESULFONIC ACID Y - 7
2gsr_A_32gsr   A     OCSCYSTEINESULFONIC ACID F - 8
2gsr_A_32gsr   A     OCSCYSTEINESULFONIC ACID V - 10
2gsr_A_32gsr   A     OCSCYSTEINESULFONIC ACID G - 12
2gsr_A_32gsr   A     OCSCYSTEINESULFONIC ACID R - 13
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1okt_A_51okt   A AC1FMT BINDING SITE FOR CHAIN AK - 15

Clusters included in this Subclass
CLUSTER: EH.6.18
CLUSTER: EH.8.125