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Information on SUBCLASS 4.28.1
Subclass Accession number: 1316
Subclass: 4.28.1 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.1 (>75 %)  1.1.1 (>75 %)  5.3 (>50 %)  5.3.1 (>50 %)  5.3.1.1
GO : GO:0004457 (>75 %)  GO:0004459 (>75 %)  GO:0016614 (>75 %)  GO:0016615 (>75 %)  GO:0016616 (>75 %)  GO:0016853 (>75 %)  GO:0016860 (>75 %)  GO:0016861 (>75 %)  
SCOP : 51351 (>75 %)  51352 (>75 %)  51734 (>75 %)  51735 (>75 %)  51848 (>75 %)  
Number of loops: 12

Average sequence ID (%) : 36.3 +/- 25.5
Average RMSD (Å) : 0.317 +/- 0.134

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: hhhpNPhD
(φψ)-conformation: bbappwaa
Pattern: [CFIKLV][filvy][FGILMV][ILMTV][AITV][AGNST][N][P][CLV][DN][AILTV][ailmt][ANTV]x[aiklv][ACFLT]x[ehkq]
Conservation:-0.703-0.418-0.4430.0870.047-0.1972.1742.6840.1471.103-0.208-0.584-0.261-0.696-0.722-0.647-0.919-0.445
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ez4_A_1321ez4   A132149IFLVAANPVDILTYATWKEEEE-SSSHHHHHHHHHHbxbbaxxwaaaaaaaaaa
1gv1_A_1131gv1   A113130IIIVVSNPLDIMTHVAWVEEEE--SSHHHHHHHHHHbbbxaxxwaaaaaaaaaa
1hye_A_1171hye   A117134KIFVITNPVDVMTYKALVEEEE-SSSHHHHHHHHHHbbbxaxxwaaaaaaaaaa
1hyh_A_1371hyh   A137154VLVVISNPVDVITALFQHEEEE-SSSHHHHHHHHHHxbbxapxwaaaaaaaaaa
1ldn_A_1321ldn   A132149LFLVATNPVDILTYATWKEEEE-SSSHHHHHHHHHHxbbbaxbwaaaaaaaaaa
1lld_A_1191lld   A119136IYMLITNPVDIATHVAQKEEEE--SSHHHHHHHHHHxbbbapxwaaaaaaaaaa
1o6z_A_1341o6z   A134151ISLTTSNPVDLLNRHLYEEEEE--SSHHHHHHHHHHxbbbapxwaaaaaaaaaa
1t2d_A_1201t2d   A120137FIIVVTNPVDVMVQLLHQEEEE-SSSHHHHHHHHHHxbbbapxwaaaaaaaaaa
1ur5_A_1141ur5   A114131VIIMVNNPLDAMTYLAAEEEEE--SSHHHHHHHHHHbxbxapbwaaaaaaaaaa
2cmd_*_1132cmd   -113130CIGIITNPVNTTVAIAAEEEEE-SSSHHHHHHHHHHxbbxapxwaaaaaaaaaa
6ldh_*_1326ldh   -132149IILVVSNPVDVLTYVAWKEEEE--SSHHHHHHHHHHbbbxapbwaaaaaaaaaa
7mdh_A_1677mdh   A167184KVLVVGNPCNTNALICLKEEEE-SSSHHHHHHHHHHxbbbaxxwaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ez4_A_1321ez4   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 135
1ez4_A_1321ez4   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 136
1ez4_A_1321ez4   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 137
1ez4_A_1321ez4   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 138
1ez4_A_1321ez4   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 140
1hye_A_1171hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 121
1hye_A_1171hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 122
1hye_A_1171hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 123
1hye_A_1171hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE V - 125
1hyh_A_1371hyh   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 141
1hyh_A_1371hyh   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 142
1hyh_A_1371hyh   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 143
1hyh_A_1371hyh   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 145
1ldn_A_1321ldn   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 137
1ldn_A_1321ldn   A     OXMOXAMIC ACID N - 138
1ldn_A_1321ldn   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE P - 139
1lld_A_1191lld   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 123
1lld_A_1191lld   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 124
1lld_A_1191lld   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 125
1lld_A_1191lld   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 127
1o6z_A_1341o6z   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 138
1o6z_A_1341o6z   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 139
1o6z_A_1341o6z   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 140
1o6z_A_1341o6z   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 142
1t2d_A_1201t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 123
1t2d_A_1201t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 124
1t2d_A_1201t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 125
1t2d_A_1201t2d   A     OXLOXALATE ION N - 126
1t2d_A_1201t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 126
1t2d_A_1201t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 128
1ur5_A_1141ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 118
1ur5_A_1141ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 119
1ur5_A_1141ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 120
1ur5_A_1141ur5   A     CDCADMIUM ION P - 121
1ur5_A_1141ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 122
1ur5_A_1141ur5   A     CDCADMIUM ION L - 122
1ur5_A_1141ur5   A     CDCADMIUM ION D - 123
1ur5_A_1141ur5   A     CDCADMIUM ION A - 124
2cmd_*_1132cmd   *     CITCITRIC ACID I - 117
2cmd_*_1132cmd   *     CITCITRIC ACID T - 118
2cmd_*_1132cmd   *     CITCITRIC ACID N - 119
2cmd_*_1132cmd   *     CITCITRIC ACID V - 121
7mdh_A_1677mdh   A     ZNZINC ION V - 170
7mdh_A_1677mdh   A     ZNZINC ION V - 171
7mdh_A_1677mdh   A     ZNZINC ION G - 172
7mdh_A_1677mdh   A     ZNZINC ION N - 173
7mdh_A_1677mdh   A     ZNZINC ION P - 174
7mdh_A_1677mdh   A     ZNZINC ION C - 175
7mdh_A_1677mdh   A     ZNZINC ION N - 176
7mdh_A_1677mdh   A     ZNZINC ION L - 180
7mdh_A_1677mdh   A     ZNZINC ION K - 184
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1ur5_A_1141ur5   A AC9CL BINDING SITE FOR CHAIN AD - 123
1ur5_A_1141ur5   A AC9CL BINDING SITE FOR CHAIN AA - 124

Clusters included in this Subclass
CLUSTER: EH.4.13