ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 5.2.2

Subclass Accession number: 1370
Subclass: 5.2.2

Type: EH beta-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.4 (>75 %)  1.4.1 (>75 %)  1.4.1.3 (>75 %)
GO : GO:0004353 (>50 %)  GO:0016638 (>50 %)  GO:0016639 (>50 %)
SCOP : 53222 (>75 %)  53223 (>75 %)  53224 (>75 %)

Number of loops: 8

Average sequence ID (%) : 16.2 +/- 16.9
Average RMSD (Å) : 0.550 +/- 0.245

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 90-135

rho (°): 180-225

Consensus Sequence:	hXhpphXXX
(φψ)-conformation:	bpaaappaa

Pattern:	x	x	[fgkv]	[dnprt]	[afipv]	[aden]	[EST]	[LMVW]	[adpt]	[KPR]	[ADEGS]	x	[aikt]
Conservation:	-1.000	-1.000	-1.317	-0.524	-0.875	0.837	1.163	1.044	-0.333	1.371	0.481	-1.205	-0.641

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bt3_A_47	1bt3	A	48	60	VRPAAHTMDKDAI	EE-BGGG--HHHH	bxxxaaaxxaaaa
1gt9_1_131	1gt9	1	131	141	..GPEDSWAPASI	..EEGGGS-HHHH	..bpaaaxxaaaa
1h16_A_736	1h16	A	736	747	.AVRFNSLTKEQQ	.EEEGGGS-HHHH	.bbxaaaxxaaaa
1js8_A_2504	1js8	A	2505	2517	IRKNVNSLTPSDI	EE-BGGG--HHHH	xbbpaaaxxaaaa
1jvw_A_112	1jvw	A	112	124	TTFRPNEVIKGWT	EEE-GGGS-HHHH	bxbxaaabxaaaa
1k7k_A_167	1k7k	A	167	177	..KTAAELTREEK	..EEGGGS-HHHH	..bxaaaxxaaaa
1nyk_A_103	1nyk	A	106	118	ARFDPEELAPEVA	EE--GGGS-HHHH	bbbpaaaxxaaaa
3gcb_*_414	3gcb	-	418	430	IVVDINELPKELA	EEEEGGGS-HHHH	bbbxaaaxxaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1h16_A_736	1h16	A	DTLD-TREITOL	S - 741
1h16_A_736	1h16	A	DTLD-TREITOL	L - 742
1h16_A_736	1h16	A	DTLD-TREITOL	T - 743
1h16_A_736	1h16	A	DTLD-TREITOL	Q - 746
1nyk_A_103	1nyk	A	MGMAGNESIUM ION	E - 112
1nyk_A_103	1nyk	A	MGMAGNESIUM ION	L - 113
1nyk_A_103	1nyk	A	MGMAGNESIUM ION	A - 114
3gcb_*_414	3gcb	*	GOLGLYCEROL	V - 419
3gcb_*_414	3gcb	*	GOLGLYCEROL	V - 420
3gcb_*_414	3gcb	*	GOLGLYCEROL	D - 421

Clusters included in this Subclass

CLUSTER: EH.6.37

CLUSTER: EH.7.38