Information on SUBCLASS 8.17.1 |
Subclass Accession number: 3494
Subclass: 8.17.1 Type: EH beta-alpha DB: ArchDB95 Image coordinates: Consensus coordinates: Conserved Annotation EC : 1 (>75 %) 1.1 (>75 %) 1.1.1 (>75 %) 4.1 (>75 %) 4.1.1 (>75 %) 4.1.1.39 GO : GO:0000287 (>50 %) GO:0004497 (>75 %) GO:0016614 (>75 %) GO:0016616 (>75 %) GO:0016830 (>75 %) GO:0016831 (>75 %) GO:0016984 (>75 %) SCOP : 51734 (>75 %) 51735 (>75 %) 51830 (>75 %) 54861 (>75 %) 54966 (>75 %) 54967 (>75 %) |
Number of loops: 4 Average sequence ID (%) : 45.5 +/- 21.0 Average RMSD (Å) : 0.350 +/- 0.058 Consensus geometry
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Consensus Sequence: | hNXXRhXLhDpp |
(φψ)-conformation: | bbaabaaabpaa |
Pattern: | [AV] | [IVY] | [IV] | [IV] | [N] | [TV] | [AS] | [R] | [GP] | [DKNP] | [L] | [CIV] | [D] | [NRT] | [DEQ] | [AL] | [MV] | [AILV] | [ARS] | [AGN] | [L] | [DEK] |
Conservation: | -0.436 | -0.601 | 0.463 | 0.494 | 2.204 | -0.131 | -0.124 | 1.508 | -0.245 | -1.278 | 0.811 | -0.488 | 2.204 | -0.851 | -0.075 | -0.723 | -0.054 | -0.930 | -1.111 | -1.118 | 0.811 | -0.330 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1dxy_*_227 | 1dxy | - | 227 | 248 | AIVINTARPNLIDTQAMLSNLK | EEEEE-S-TTSB-HHHHHHHHH | xbbbbaabaaabxaaaaaaaaa |
1gdh_A_233 | 1gdh | A | 233 | 254 | AIVVNTARGDLVDNELVVAALE | EEEEE-S-GGGB-HHHHHHHHH | xbbbbaabaaabxaaaaaaaaa |
1j4a_A_229 | 1j4a | A | 229 | 250 | VVIVNVSRGPLVDTDAVIRGLD | EEEEE-S-GGGB-HHHHHHHHH | xbbbbaabaaabxaaaaaaaaa |
2nac_A_277 | 2nac | A | 277 | 298 | AYIVNTARGKLCDRDAVARALE | EEEEE-S-GGGB-HHHHHHHHH | xbbbbaabaaabxaaaaaaaaa |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1dxy_*_227 | 1dxy | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | T - 232 |
1dxy_*_227 | 1dxy | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | A - 233 |
1dxy_*_227 | 1dxy | * | COI2-OXO-4-METHYLPENTANOIC ACID | A - 233 |
1dxy_*_227 | 1dxy | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | R - 234 |
1dxy_*_227 | 1dxy | * | COI2-OXO-4-METHYLPENTANOIC ACID | R - 234 |
1j4a_A_229 | 1j4a | A | SULSULFATE ANION | S - 235 |
1j4a_A_229 | 1j4a | A | SULSULFATE ANION | R - 236 |
1j4a_A_229 | 1j4a | A | SULSULFATE ANION | G - 237 |
1j4a_A_229 | 1j4a | A | SULSULFATE ANION | P - 238 |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
1dxy_*_227 | 1dxy | * | CATACTIVE SITE. | T - 232 |
1dxy_*_227 | 1dxy | * | CATACTIVE SITE. | R - 234 |
Clusters included in this Subclass |
CLUSTER: EH.7.128 |