Information on SUBCLASS 12.1.2 |
Subclass Accession number: 6590
Subclass: 12.1.2 Type: HA beta-beta hairpin DB: ArchDB95 Image coordinates: Consensus coordinates: Conserved Annotation EC : 3.4 (>50 %) 3.4.21 (>50 %) 3.4.21 (>50 %) GO : GO:0004175 (>75 %) GO:0004252 (>75 %) GO:0004252 (>75 %) GO:0005509 (>50 %) GO:0008233 (>75 %) GO:0008236 (>75 %) GO:0008236 (>75 %) SCOP : 50493 (>75 %) 50493 (>75 %) 50494 (>75 %) 50494 (>75 %) 50514 (>75 %) 50514 (>75 %) |
Number of loops: 3 Average sequence ID (%) : 20.0 +/- 17.5 Average RMSD (Å) : 0.267 +/- 0.058 Consensus geometry
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Consensus Sequence: | XXpXXhcXXXXXcDhX |
(φψ)-conformation: | bppaapbaaalplpbb |
Pattern: | x | [FIT] | [PSV] | [HY] | [EPS] | x | [FY] | [DN] | [PS] | x | [TV] | x | x | [GN] | [D] | [ILV] | [AK] | [LV] | [IL] | [KQR] |
Conservation: | -1.152 | -0.766 | -1.023 | 1.595 | -0.573 | -0.830 | 1.600 | 0.784 | 0.377 | -1.216 | 0.156 | -1.087 | -1.152 | 0.515 | 2.126 | 0.198 | -0.296 | 0.177 | 0.432 | 0.134 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1azz_A_88 | 1azz | A | 88 | 107 | FTVHENYNSFVISNDIAVIR | EEE-TT-BTTTTBS--EEEE | bbxpaaxbaaalblxbbbbx |
1orf_A_85 | 1orf | A | 88 | 107 | EFPYPCYDPATREGDLKLLQ | EEE-TT--TTT-TT--EEEE | xbxpaapbaaavxlxbbxbx |
2hlc_A_87 | 2hlc | A | 88 | 107 | IISHSMFNPDTYLNDVALIK | EEE-TT-BTTTTBT--EEEE | bbxpaaxbaaavxlxbbbbx |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1orf_A_85 | 1orf | A | DPND-PHENYLALANINE | R - 99 |
1orf_A_85 | 1orf | A | MAIDEOXO-METHYLARGININE | D - 102 |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
2hlc_A_87 | 2hlc | A | CTANULL | D - 102 |
Clusters included in this Subclass |
CLUSTER: HA.12.12 |