ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 3.3.2

Subclass Accession number: 8319
Subclass: 3.3.2

Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 23

Average sequence ID (%) : 13.3 +/- 15.2
Average RMSD (Å) : 0.839 +/- 0.208

Consensus geometry

d (Å): 9

delta (°): 45-90

theta (°): 135-180

rho (°): 135-180

Consensus Sequence:	XpXXphX
(φψ)-conformation:	aapaabb

Pattern:	x	x	[aegknrs]	x	[afiklv]	x	[adeknqst]	x	[dekps]	[adeknrs]	[ACFIKLMTV]	x	x
Conservation:	0.032	-1.333	-0.658	-0.915	1.304	-0.950	0.886	-0.142	1.204	0.891	1.369	-0.814	-0.874

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1amu_A_442	1amu	A	445	457	VESILLKHMYISE	HHHHHTTSTTEEE	aaaaaaapaaxab
1aqu_A_172	1aqu	A	178	190	AWWEKSKNSRVLF	HHHHHTTSTTEEE	aaaaaaaxaabxb
1ati_A_36	1ati	A	50	62	WRRNVYERDDMEG	HHHHTTS-SSEEE	aaaaaaabaabbx
1bgv_A_352	1bgv	A	354	366	ALRFLMQQPNMVV	HHHHHHH-TT-EE	aaaaaaaxaaxbb
1dhp_A_145	1dhp	A	147	159	TVGRLAKVKNIIG	HHHHHTTSTTEEE	aaaaaaaxaaxab
1din_*_176	1din	-	182	194	ITEGFGANPLLQV	HHHHHTT-TTEEE	aaaaaaabaaxbb
1e6u_A_14	1e6u	A	19	31	IRRQLEQRGDVEL	HHHHHTT-TTEEE	aaaaaaabaabbx
1ep3_A_110	1ep3	A	116	128	VCAKIGDAANVKA	HHHHHTTSTTEEE	aaaaaaaxaaxab
1f06_A_13	1f06	A	18	30	VEKLIAKQPDMDL	HHHHHTT-SSEEE	aaaaaaaxaabbx
1f6k_A_148	1f6k	A	150	162	QFGELYKNPKVLG	HHHHHHTSTTEEE	aaaaaaaxaaxae
1feh_A_211	1feh	A	213	225	RVKNALNAPEKHV	HHHHHHH-TT-EE	aaaaaaaxaaxxx
1g3m_A_171	1g3m	A	177	189	SWWEKGKSPRVLF	HHHHHTTSTTEEE	aaaaaaaxaabxx
1gad_O_10	1gad	O	15	27	VFRAAQKRSDIEI	HHHHHHT-SSEEE	aaaaaaabaabbx
1gd1_O_10	1gd1	O	15	27	VFRAALKNPDIEV	HHHHHTT-SSEEE	aaaaaaabaabbx
1itw_A_65	1itw	A	68	80	ELGKLATTPDANI	HHHHHTTSTT-EE	aaaaaaabaapbb
1jy1_A_232	1jy1	A	238	250	LHAQAKPYENISL	HHHHHTT-TTEEE	aaaaaaabaabbb
1kam_A_53	1kam	A	60	72	LKLAIQSNPSFKL	HHHHHTT-TTEEE	aaaaaaabaaxbb
1l8a_A_645	1l8a	A	645	657	SHIQSLTIPNCIS	HHHHHTTSTTEEE	aaaaaaaxaabbb
1lci_*_451	1lci	-	454	466	LESILLQHPNIFD	HHHHHHTSTTEEE	aaaaaaaxaaxab
1lk9_A_314	1lk9	A	329	341	ITALLDQSDRFSY	HHHHHTT-SSEEE	aaaaaaabaabbb
1mdb_A_442	1mdb	A	445	457	VENHLLAHPAVHD	HHHHHTTSTTEEE	aaaaaaaxaabab
1php_*_329	1php	-	334	346	IAEALAEALDTYS	HHHHHHH-TT-EE	aaaaaaaxaabxb
1vgv_A_249	1vgv	A	255	267	VNRILGHVKNVIL	HHHHHTT-TTEEE	aaaaaaaxaabbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1e6u_A_14	1e6u	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	M - 14
1e6u_A_14	1e6u	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	V - 15
1e6u_A_14	1e6u	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	G - 16
1e6u_A_14	1e6u	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	S - 17
1e6u_A_14	1e6u	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	R - 20
1e6u_A_14	1e6u	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	R - 21
1ep3_A_110	1ep3	A	FMNFLAVIN MONONUCLEOTIDE	E - 130
1ep3_A_110	1ep3	A	FMNFLAVIN MONONUCLEOTIDE	L - 131
1ep3_A_110	1ep3	A	FMNFLAVIN MONONUCLEOTIDE	N - 132
1f06_A_13	1f06	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	N - 13
1f06_A_13	1f06	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	L - 14
1f06_A_13	1f06	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	G - 15
1f06_A_13	1f06	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	I - 33
1f06_A_13	1f06	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	F - 34
1f06_A_13	1f06	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	S - 35
1feh_A_211	1feh	A	HC12 IRON/2 SULFUR/5 CARBONYL/2 WATER INORGANIC CLUSTER	M - 229
1g3m_A_171	1g3m	A	EDO1,2-ETHANEDIOL	K - 173
1g3m_A_171	1g3m	A	EDO1,2-ETHANEDIOL	K - 176
1g3m_A_171	1g3m	A	EDO1,2-ETHANEDIOL	S - 177
1g3m_A_171	1g3m	A	EDO1,2-ETHANEDIOL	W - 178
1g3m_A_171	1g3m	A	EDO1,2-ETHANEDIOL	E - 180
1gad_O_10	1gad	O	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	R - 10
1gad_O_10	1gad	O	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	I - 11
1gad_O_10	1gad	O	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 12
1gad_O_10	1gad	O	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	R - 13
1gad_O_10	1gad	O	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	N - 31
1lk9_A_314	1lk9	A	NAGN-ACETYL-D-GLUCOSAMINE	K - 321
1lk9_A_314	1lk9	A	NAGN-ACETYL-D-GLUCOSAMINE	E - 324
1lk9_A_314	1lk9	A	NAGN-ACETYL-D-GLUCOSAMINE	R - 325
1lk9_A_314	1lk9	A	NAGN-ACETYL-D-GLUCOSAMINE	N - 328

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1dhp_A_145	1dhp	A	S1PYRUVATE BINDING RESIDUE.	K - 161
1e6u_A_14	1e6u	A	AC1NAP BINDING SITE FOR CHAIN A	M - 14

Clusters included in this Subclass