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Information on SUBCLASS 3.3.2
Subclass Accession number: 5477
Subclass: 3.3.2 PSSM
Type: HE alpha-beta
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 61

Average sequence ID (%) : 13.5 +/- 15.4
Average RMSD (Å) : 0.728 +/- 0.237

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 270-315
Consensus Sequence: XXphpXh
(φψ)-conformation: aalpabb
Pattern: [adegknqrst]x[afilmv]xxx[adegknqrs][acfilpvy][adegknqrst]x[acfgilmvwy][acfgilmvwy]
Conservation:-0.771-1.6540.928-0.223-0.272-0.9571.2670.1760.416-1.1301.4410.779
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a05_A_871a05   A93104RLRKGLDLYANLHHHHHHT--EEEaaaaaalxabxb
1a9x_B_17251a9x   B17261737EDVLKMNPDGIFHHHHTT--SEEEaaaaaavxabbb
1ako_*_151ako   -2031AIVEKHQPDVIGHHHHHH--SEEEaaaaaalxabbb
1ass_*_501ass   -6677EKIKKSGANVVLHHHHHTT-SEEEaaaaaagpabbb
1b0u_A_1561b0u   A165176ARALAMEPDVLLHHHHHT--SEEEaaaaaalxabbb
1bxk_A_631bxk   A6879RVFTEHQPDCVMHHHHHH--SEEEaaaaaalxabbb
1bzy_A_1401bzy   A147158SLVRQYNPKMVKHHHHTT--SEEEaaaaaalxabbb
1c4x_A_811c4x   A94105GLMNHFGIEKSHHHHHHHT-SSEEaaaaaavxabbx
1cm7_A_901cm7   A97108PLRKHFKLFSNLHHHHHTT--EEEaaaaaavxabbb
1cnz_A_921cnz   A97108PLRKHFKLFSNLHHHHHHT--EEEaaaaaalxabbb
1coz_A_771coz   A7990QDIIDHNIDVFVHHHHHTT-SEEEaaaaaalxabbb
1cs1_A_1271cs1   A131142RAALAEKPKLVLHHHHHT--SEEEaaaaaalxabbx
1db3_A_671db3   A7283RILREVQPDEVYHHHHHH--SEEEaaaaaalxabbb
1ddz_A_1821ddz   A190201YAVQYLKVKHILHHHHTS--SEEEaaaaaalxabbb
1e3m_A_1681e3m   A168179AELQRTNPAELLHHHHHH--SEEEaaaaaalpabbx
1e5d_A_881e5d   A90101ALIEACQPEKIFHHHHHH--SEEEaaaaaalxabbx
1e6u_A_441e6u   A4960DFFASERIDQVYHHHHHH--SEEEaaaaaalxabbb
1efd_N_891efd   N90101ELLTEMKPSFMVHHHHHH--SEEEaaaaaalxabbb
1efv_A_891efv   A98109ATQKQFNYTHICHHHHHH--SEEEaaaaaalxabbb
1g55_A_621g55   A6374EEFDRLSFDMILHHHHHH--SEEEaaaaaalxabbb
1g5c_A_641g5c   A7283VAIYALGDNEIIHHHHHH---EEEaaaaaavxabbb
1g6h_A_1561g6h   A165176GRALMTNPKMIVHHHHHT--SEEEaaaaaalxabbb
1gg4_A_1661gg4   A169180WTVSLTRPEAALHHHHHH--SEEEaaaaaalxabbb
1gml_A_2641gml   A280291EDIIQLKPDVVIHHHHTT--SEEEaaaaaalxabbb
1gpm_A_431gpm   A4455AQIRDFNPSGIIHHHHHH--SEEEaaaaaalxabbb
1gr0_A_1301gr0   A132143QALKEAKVDVLVHHHHHTT-SEEEaaaaaalxabbb
1hjr_A_401hjr   A5364EIITQFQPDYFAHHHHHH--SEEEaaaaaavxabbb
1hp1_A_981hp1   A102113RGMNLVGYDAMAHHHHHHT--EEEaaaaaavxabbx
1hrd_A_3281hrd   A332343KKIVANNVKYYIHHHHHTT--EEEaaaaaalxabbb
1i24_A_791i24   A8495ESFKSFEPDSVVHHHHHH--SEEEaaaaaalxabbb
1ihn_A_601ihn   A6374EELLEEKPESIIHHHHTT--SEEEaaaaaalxabbb
1iho_A_1261iho   A136147KLFNLVQPDIACHHHHHH--SEEEaaaaaalxabbb
1iuk_A_871iuk   A8899PEVLALRPGLVWHHHHHH--S-EEaaaaaalxabbb
1iwe_A_3441iwe   A349360YAHMVNGFTALAHHHHHH--SEEEaaaaaalpabbb
1j0h_A_3031j0h   A315326YWIREFDIDGWRHHHHHH---EEEaaaaaavxabbx
1jla_A_5001jla   A503513LGIIQAQPDQS.HHHHHH--SEE.aaaaaalxabb.
1kcf_A_911kcf   A104115TLHEKFNPHVILHHHHHH--SEEEaaaaaalxabbb
1kht_A_1071kht   A108119WVLNELNPDLIIHHHHHH--SEEEaaaaaalxabbb
1l2t_A_1481l2t   A157168ARALANNPPIILHHHHTT--SEEEaaaaaalxabbb
1lc5_A_851lc5   A91102TVASGLKPRRAMHHHHHH--SEEEaaaaaalxabbb
1mxi_A_631mxi   A6576AFLESEKPKRLFHHHHHH--SEEEaaaaaalpabbb
1n2z_A_2011n2z   A202213EQVLARSPQAIVHHHHTT--SEEEaaaaaalxabbb
1n7h_A_951n7h   A100111RWIDVIKPDEVYHHHHHH--SEEEaaaaaalxabbb
1o0s_A_3901o0s   A392403EVIRAARPGALIHHHHHH--SEEEaaaaaalxabbb
1orr_A_621orr   A6778RLITKYMPDSCFHHHHHH--SEEEaaaaaalxabbb
1pb1_A_1141pb1   A117128ALRQELDLYICLHHHHHTT--EEEaaaaaalxabbb
1pq4_A_2691pq4   A277288DTAKENNLTMVFHHHHTTT--EEEaaaaaalxabbb
1q3q_A_2621q3q   A281292DHIAQTGANVVFHHHHHHT--EEEaaaaaagpabbb
1q8i_A_2011q8i   A210221AWFANYDPDVIIHHHHHH--SEEEaaaaaalxabbb
1qht_A_1871qht   A196207RVVREKDPDVLIHHHHHH--SEEEaaaaaalxabbb
1qjc_A_741qjc   A7687NFARNQHATVLIHHHHHTT--EEEaaaaaalxabbx
1qv9_A_571qv9   A5869DIAEDFEPDFIVHHHHHH--SEEEaaaaaalxabbb
1rj9_B_2261rj9   B232243AFDEKVGVTGLVHHHHHH---EEEaaaaaavxabbb
1rkx_A_691rkx   A7485ESIREFQPEIVFHHHHHH--SEEEaaaaaalxabbb
1s4n_A_2601s4n   A262273KWMQENEKVYGFHHHHHTT--EEEaaaaaalbabbb
1ui0_A_1051ui0   A107118KQIELIAPQIIVHHHHHH--SEEEaaaaaalxabbb
1vjn_A_1421vjn   A147158EVADLLNAKVIIHHHHHTT-SEEEaaaaaalxaxbb
1vjo_A_1361vjo   A141152TALETHRPAILAHHHHHH--SEEEaaaaaalxabbb
1vrt_A_5001vrt   A503513LGIIQAQPDQS.HHHHHT--SEE.aaaaaalxabb.
1xva_A_421xva   A5061GLLRQHGCHRVLHHHHHTT--EEEaaaaaavxaxbb
1yac_A_941yac   A98109KAVKATGKKQLIHHHHHTT-SEEEaaaaaavxaxbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID E - 88
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID L - 91
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID L - 92
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID R - 95
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID R - 105
1a05_A_871a05   A     MGMAGNESIUM ION R - 105
1a9x_B_17251a9x   B     CYG2-AMINO-4-(AMINO-3-OXO-PROPYLSULFANYLCARBONYL)-BUTYRIC ACID L - 1738
1ass_*_501ass   *     PO4PHOSPHATE ION I - 50
1b0u_A_1561b0u   A     ATPADENOSINE-5'-TRIPHOSPHATE D - 178
1bxk_A_631bxk   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 80
1bzy_A_1401bzy   A     IMUPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN -2-YLMETHYL] ESTER K - 140
1bzy_A_1401bzy   A     IMUPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN -2-YLMETHYL] ESTER T - 141
1bzy_A_1401bzy   A     POPPYROPHOSPHATE 2- T - 141
1bzy_A_1401bzy   A     MGMAGNESIUM ION T - 141
1bzy_A_1401bzy   A     IMUPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN -2-YLMETHYL] ESTER M - 142
1bzy_A_1401bzy   A     IMUPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN -2-YLMETHYL] ESTER K - 165
1cnz_A_921cnz   A     MNMANGANESE (II) ION R - 109
1coz_A_771coz   A     CTPCYTIDINE-5'-TRIPHOSPHATE V - 90
1coz_A_771coz   A     CTPCYTIDINE-5'-TRIPHOSPHATE M - 91
1coz_A_771coz   A     CTPCYTIDINE-5'-TRIPHOSPHATE G - 92
1cs1_A_1271cs1   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) E - 144
1ddz_A_1821ddz   A     ZNZINC ION H - 205
1e3m_A_1681e3m   A     MSESELENOMETHIONINE A - 168
1e3m_A_1681e3m   A     MSESELENOMETHIONINE E - 169
1e3m_A_1681e3m   A     MSESELENOMETHIONINE L - 170
1e3m_A_1681e3m   A     MSESELENOMETHIONINE Q - 171
1e3m_A_1681e3m   A     MSESELENOMETHIONINE R - 172
1e3m_A_1681e3m   A     MSESELENOMETHIONINE Y - 180
1e3m_A_1681e3m   A     MSESELENOMETHIONINE A - 181
1e6u_A_441e6u   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 61
1g55_A_621g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE M - 75
1g5c_A_641g5c   A     ZNZINC ION H - 87
1g5c_A_641g5c   A     EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID H - 87
1g6h_A_1561g6h   A     MGMAGNESIUM ION D - 178
1g6h_A_1561g6h   A     ADPADENOSINE-5'-DIPHOSPHATE D - 178
1gg4_A_1661gg4   A     MSESELENOMETHIONINE A - 179
1gg4_A_1661gg4   A     MSESELENOMETHIONINE L - 180
1gg4_A_1661gg4   A     MSESELENOMETHIONINE V - 181
1gr0_A_1301gr0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 144
1i24_A_791i24   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 96
1ihn_A_601ihn   A     MSESELENOMETHIONINE E - 61
1ihn_A_601ihn   A     MSESELENOMETHIONINE L - 62
1ihn_A_601ihn   A     MSESELENOMETHIONINE I - 75
1ihn_A_601ihn   A     MSESELENOMETHIONINE G - 76
1iho_A_1261iho   A     EDO1,2-ETHANEDIOL G - 129
1iho_A_1261iho   A     EDO1,2-ETHANEDIOL V - 130
1iho_A_1261iho   A     EDO1,2-ETHANEDIOL I - 133
1iho_A_1261iho   A     EDO1,2-ETHANEDIOL V - 134
1iho_A_1261iho   A     EDO1,2-ETHANEDIOL L - 137
1iho_A_1261iho   A     EDO1,2-ETHANEDIOL F - 148
1l2t_A_1481l2t   A     ATPADENOSINE-5'-TRIPHOSPHATE G - 148
1l2t_A_1481l2t   A     ATPADENOSINE-5'-TRIPHOSPHATE G - 149
1l2t_A_1481l2t   A     ATPADENOSINE-5'-TRIPHOSPHATE Q - 150
1l2t_A_1481l2t   A     ATPADENOSINE-5'-TRIPHOSPHATE R - 153
1l2t_A_1481l2t   A     ATPADENOSINE-5'-TRIPHOSPHATE D - 170
1lc5_A_851lc5   A     PIHYDROGENPHOSPHATE ION E - 85
1lc5_A_851lc5   A     PIHYDROGENPHOSPHATE ION T - 86
1lc5_A_851lc5   A     PIHYDROGENPHOSPHATE ION E - 87
1mxi_A_631mxi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE A - 77
1mxi_A_631mxi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE L - 78
1n2z_A_2011n2z   A     CDCADMIUM ION I - 214
1n2z_A_2011n2z   A     CDCADMIUM ION T - 215
1n7h_A_951n7h   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 112
1o0s_A_3901o0s   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE G - 404
1orr_A_621orr   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 79
1pb1_A_1141pb1   A     ICIISOCITRIC ACID L - 114
1pb1_A_1141pb1   A     ICIISOCITRIC ACID N - 115
1pb1_A_1141pb1   A     ICIISOCITRIC ACID V - 116
1pb1_A_1141pb1   A     ICIISOCITRIC ACID R - 119
1pb1_A_1141pb1   A     GOLGLYCEROL I - 126
1pb1_A_1141pb1   A     ICIISOCITRIC ACID C - 127
1pb1_A_1141pb1   A     GOLGLYCEROL L - 128
1pb1_A_1141pb1   A     ICIISOCITRIC ACID R - 129
1qv9_A_571qv9   A     MSESELENOMETHIONINE L - 57
1qv9_A_571qv9   A     MSESELENOMETHIONINE D - 58
1qv9_A_571qv9   A     MSESELENOMETHIONINE I - 59
1qv9_A_571qv9   A     MSESELENOMETHIONINE A - 60
1qv9_A_571qv9   A     MSESELENOMETHIONINE V - 69
1qv9_A_571qv9   A     MSESELENOMETHIONINE Y - 70
1qv9_A_571qv9   A     MSESELENOMETHIONINE G - 71
1rj9_B_2261rj9   B     GCPPHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER L - 244
1rj9_B_2261rj9   B     GCPPHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER T - 245
1vjn_A_1421vjn   A     MSESELENOMETHIONINE I - 158
1vjo_A_1361vjo   A     PLPPYRIDOXAL-5'-PHOSPHATE V - 154
1xva_A_421xva   A     SAMS-ADENOSYLMETHIONINE Y - 44
1xva_A_421xva   A     SAMS-ADENOSYLMETHIONINE D - 62

Clusters included in this Subclass
CLUSTER: HE.2.37
CLUSTER: HE.3.14
CLUSTER: HE.3.233
CLUSTER: HE.4.42
CLUSTER: HE.4.52
CLUSTER: HE.5.130
CLUSTER: HE.5.346
CLUSTER: HE.6.280