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Information on SUBCLASS 5.2.3
Subclass Accession number: 5747
Subclass: 5.2.3 PSSM
Type: HE alpha-beta
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.2 (>50 %)  1.2.1 (>50 %)  
GO : GO:0016620 (>50 %)  GO:0016903 (>50 %)  
SCOP : 53719 (>75 %)  53720 (>75 %)  53721 (>75 %)  
 Number of loops: 9

Average sequence ID (%) : 33.9 +/- 28.8
Average RMSD (Å) : 0.400 +/- 0.158

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 90-135 rho (°): 90-135
Consensus Sequence: hXpXphXXV
(φψ)-conformation: aapaapabb
Pattern: xxx[acmv]x[dhw][adepq][adenr][itv][adknr][aefk][iv][agns][cf][gt]
Conservation:-0.883-1.1040.063-0.533-0.8540.977-0.809-0.4730.871-0.681-1.0081.803-0.0051.6251.010
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a4s_A_2221a4s   A226240SLLCHHPNVAKVSFTHHHHH-TT--EEEEEaaaaaxaaxabbbbb
1bxs_A_2281bxs   A230244AAISSHMDVDKVAFTHHHHT-TT-SEEEEEaaaaaxaababbbbb
1euh_A_2101euh   A215229DYIVEHQAVNFINFTHHHHH-TT--EEEEEaaaaapaaxabbbbb
1ez0_A_2111ez0   A214228QALVSHPEIKAVGFTHHHHH-TT--EEEEEaaaaaxaaxabbbbb
1ky8_A_2281ky8   A228242EKIVADDRVAAVSFTHHHHH-TT--EEEEEaaaaaxaaxabbxbb
1o04_A_2281o04   A230244AAIASHEDVDKVAFTHHHHT-TT--EEEEEaaaaaxaaxabbbbb
1o9j_A_2281o9j   A230244AAISSHMDVDKVAFTHHHHT-TT--EEEEEaaaaaxaaxabbbbb
1qnx_A_1511qnx   A157171YTQMVWANTKEVGCGHHHHT-TT--EEEEEaaaaaxaaxabbbbb
1uzb_A_2421uzb   A245259AYLVEHPRIRFINFTHHHHT-TT--EEEEEaaaaaxaaxabbbbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bxs_A_2281bxs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 229
1bxs_A_2281bxs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 230
1bxs_A_2281bxs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 233
1bxs_A_2281bxs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE F - 243
1bxs_A_2281bxs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 244
1ez0_A_2111ez0   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE A - 211
1ez0_A_2111ez0   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 212
1ez0_A_2111ez0   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 213
1ez0_A_2111ez0   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Q - 214
1ez0_A_2111ez0   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 227
1ez0_A_2111ez0   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 228
1ky8_A_2281ky8   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 228
1ky8_A_2281ky8   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE V - 231
1ky8_A_2281ky8   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 241
1ky8_A_2281ky8   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 242
1o04_A_2281o04   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 228
1o04_A_2281o04   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 231
1o04_A_2281o04   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 233
1o04_A_2281o04   A     GAIGUANIDINE D - 239
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1o9j_A_2281o9j   A NDANAD BINDING SITE FOR CHAIN AG - 229
1o9j_A_2281o9j   A NDANAD BINDING SITE FOR CHAIN AA - 230
1o9j_A_2281o9j   A NDANAD BINDING SITE FOR CHAIN AF - 243
1o9j_A_2281o9j   A NDANAD BINDING SITE FOR CHAIN AT - 244

Clusters included in this Subclass
CLUSTER: HE.5.259
CLUSTER: HE.6.46