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Information on SUBCLASS 1.2.3
Subclass Accession number: 1001
Subclass: 1.2.3 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.4 (>50 %)  3.4.25 (>50 %)  3.4.25.1
SCOP : 56234 (>75 %)  56235 (>75 %)  56251 (>75 %)  
 Number of loops: 16

Average sequence ID (%) : 16.9 +/- 19.4
Average RMSD (Å) : 0.419 +/- 0.160

Consensus geometry
d (Å): 5 delta (°): 45-90 theta (°): 90-135 rho (°): 135-180
Consensus Sequence: hXcXX
(φψ)-conformation: bbeaa
Pattern: [acgilvy]x[CDGS]x[aegks][afklmv]x
Conservation:-0.214-0.6141.872-1.1800.4370.321-0.622
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bup_A_491bup   A5056LIGDAAKEETHHHHbbeaaaa
1cfz_A_741cfz   A7783LRDEEVPEETTHHHbbeaaaa
1dci_A_1691dci   A170176CIGGGVDEETHHHHbbeaaaa
1ef8_A_1061ef8   A107113VWGGAFEEETHHHHbbeaaaa
1fep_A_1211fep   A125131LRGPAAAEETHHHHbbeaaaa
1hzd_A_1811hzd   A183189ALGGGLEEETHHHHbbeaaaa
1k9v_F_3791k9v   F382388GVCLGMQEETHHHHxbeaaaa
1nt4_A_1981nt4   A199205VSGPLKVEESHHHHbbeaaaa
1nzy_A_1101nzy   A111117AAGGGLGEETHHHHbbeaaaa
1oao_C_1821oao   C185191ICDEAVEEETHHHHbbeaaaa
1qtr_A_1071qtr   A111117GGSWGSTEETHHHHbbeaaaa
1qz5_A_531qz5   A5359YVGDEAQEETHHHHbbeaaaa
1r89_A_4131r89   A415421ISGEKLFEETHHHHbbeaaaa
1su8_A_4701su8   A473479ATGCGAGEEHHHHHbbeaaaa
1tht_A_1081tht   A112118AASLSAREETHHHHbbeaaaa
1uyr_A_17321uyr   A17321738SVGIGAYEETHHHHbbeaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1fep_A_1211fep   A     MSESELENOMETHIONINE V - 124
1fep_A_1211fep   A     MSESELENOMETHIONINE R - 126
1fep_A_1211fep   A     MSESELENOMETHIONINE P - 128
1nt4_A_1981nt4   A     G1PALPHA-D-GLUCOSE-1-PHOSPHATE N - 207
1nt4_A_1981nt4   A     G1PALPHA-D-GLUCOSE-1-PHOSPHATE D - 211
1nzy_A_1101nzy   A     CACALCIUM ION V - 110
1nzy_A_1101nzy   A     BCA4-HYDROXYBENZOYL COENZYME A V - 110
1nzy_A_1101nzy   A     CACALCIUM ION A - 112
1nzy_A_1101nzy   A     BCA4-HYDROXYBENZOYL COENZYME A A - 112
1nzy_A_1101nzy   A     CACALCIUM ION G - 113
1nzy_A_1101nzy   A     BCA4-HYDROXYBENZOYL COENZYME A G - 113
1nzy_A_1101nzy   A     CACALCIUM ION G - 114
1nzy_A_1101nzy   A     BCA4-HYDROXYBENZOYL COENZYME A G - 114
1nzy_A_1101nzy   A     CACALCIUM ION G - 115
1nzy_A_1101nzy   A     BCA4-HYDROXYBENZOYL COENZYME A G - 115
1su8_A_4701su8   A     NFSFE(4)-NI(1)-S(5) CLUSTER T - 474
1su8_A_4701su8   A     NFSFE(4)-NI(1)-S(5) CLUSTER G - 475
1su8_A_4701su8   A     NFSFE(4)-NI(1)-S(5) CLUSTER C - 476
1su8_A_4701su8   A     NFSFE(4)-NI(1)-S(5) CLUSTER G - 477
1uyr_A_17321uyr   A     D1L2-[4-(2,4-DICHLOROPHENOXY)PHENOXY]PROPANOIC ACID V - 1733
1uyr_A_17321uyr   A     D1L2-[4-(2,4-DICHLOROPHENOXY)PHENOXY]PROPANOIC ACID G - 1734
1uyr_A_17321uyr   A     D1L2-[4-(2,4-DICHLOROPHENOXY)PHENOXY]PROPANOIC ACID I - 1735
1uyr_A_17321uyr   A     D1L2-[4-(2,4-DICHLOROPHENOXY)PHENOXY]PROPANOIC ACID G - 1736
1uyr_A_17321uyr   A     D1L2-[4-(2,4-DICHLOROPHENOXY)PHENOXY]PROPANOIC ACID Y - 1738
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1uyr_A_17321uyr   A AC1D1L BINDING SITE FOR CHAIN AI - 1735
1uyr_A_17321uyr   A AC1D1L BINDING SITE FOR CHAIN AY - 1738

Clusters included in this Subclass
CLUSTER: EH.0.24
CLUSTER: EH.1.36
CLUSTER: EH.2.72