ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 2.4.1

Subclass Accession number: 109
Subclass: 2.4.1
Type: HE alpha-beta
DB: ArchDB-KI

Number of loops: 9

Average sequence ID (%) : 18.1 +/- 5.7
Average RMSD (Å) : 0.76 +/- 0.50

Consensus geometry

d (Å): 7

delta (°): 90-135

theta (°): 90-135

rho (°): 90-135

Consensus Sequence:	pXXphX
(φψ)-conformation:	aalabb

Pattern:	{GLP}	{ILVY}	[FIVY]	{DEKS}	x	{FMY}	x	[EKQT]	x	{DGN}	x	[FLTVW]	x	x	[AIVW]	x
Conservation:	-0.379	-0.033	1.310	0.533	0.012	1.267	-0.694	1.504	-0.920	1.504	-1.254	-0.317	-0.579	-1.681	0.377	-0.650

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ake_A_178	1ake	A	180	195	GYYSKEAEAGNTKYAK	HHHHHHHHTTSSEEEE	aaaaaaaaavabbbbx
1aky_*_186	1aky	-	186	201	PIVDFYKKTGIWAGVD	HHHHHHHHHT-EEEEE	aaaaaaaaavaxbbbx
1gky_*_55	1gky	-	56	71	DEFKSMIKNNEFIEWA	HHHHHHHHTT-EEEEE	aaaaaaaaalababbb
1qf9_A_156	1qf9	A	158	173	LVIDHYNKFDKVKIIP	HHHHHHHHTT-EEEEE	aaaaaaaaavabbxbx
1uky_*_168	1uky	-	169	184	PVIEYFETKSKVVRVR	HHHHHHHHTT-EEEEE	aaaaaaaaalabbxbx
1ukz_*_168	1ukz	-	169	184	PVIEYFETKSKVVRVR	HHHHHHHTTT-EEEEE	aaaaaaaaalabbxbx
1zip_*_181	1zip	-	181	196	PLVDFYEQKGYLRNIN	HHHHHHHHHT-EEEEE	aaaaaaaaavaxbxbx
2eck_A_178	2eck	A	180	195	GYYSKEAEAGNTKYAK	HHHHHHHHHTSSEEEE	aaaaaaaaavabbxbb
3adk_*_158	3adk	-	159	174	PVIAFYEKRGIVRKVN	HHHHHHTTTT-EEEEE	aaaaaaaaavaxbxbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1gky_*_55	1gky	*	5GPGUANOSINE-5'-MONOPHOSPHATE	E - 69
1gky_*_55	1gky	*	5GPGUANOSINE-5'-MONOPHOSPHATE	W - 70
1gky_*_55	1gky	*	5GPGUANOSINE-5'-MONOPHOSPHATE	A - 71
1gky_*_55	1gky	*	5GPGUANOSINE-5'-MONOPHOSPHATE	F - 73
2eck_A_178	2eck	A	ADPADENOSINE-5'-DIPHOSPHATE	D - 197

Clusters included in this Subclass

CLUSTER: HE.3.16

CLUSTER: HE.3.3

CLUSTER: HE.4.22