ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.4.2

Subclass Accession number: 110
Subclass: 2.4.2
Type: HE alpha-beta
DB: ArchDB-KI

Number of loops: 4

Average sequence ID (%) : 33.9 +/- 1.2
Average RMSD (Å) : 0.42 +/- 0.20

Consensus geometry

d (Å): 3

delta (°): 90-135

theta (°): 90-135

rho (°): 135-180

Consensus Sequence:	KpGhhp
(φψ)-conformation:	aalabb

Pattern:	{AIP}	[DEK]	x	[ILV]	{K}	{K}	[R]	[FL]	{AEK}	{A}	[FY]	[EHN]	{AV}	[Q]	[T]	[EKT]	[LP]	[ILV]	[ILV]	[DE]	{FY}	[Y]	[KNRS]	[K]	{KRT}	[DG]	{IV}	{LVW}	{AEK}	{AGI}	[FIV]	[DPS]
Conservation:	-1.481	-0.010	-0.372	0.063	-0.341	-0.554	1.474	-0.031	-0.964	-0.095	1.552	0.058	-0.602	1.474	1.474	-0.528	-0.137	0.129	0.111	0.749	0.630	2.657	-0.594	1.474	-1.296	0.243	-0.808	-1.370	-0.816	-1.370	-0.178	-0.543

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ak2_*_181	1ak2	-	181	212	KKALKIRLEAYHTQTTPLVEYYSKRGIHSAID	HHHHHHHHHHHHHHHHHHHHHHHHTT-EEEEE	aaaaaaaaaaaaaaaaaaaaaaaaavaxbbbx
1dvr_A_170	1dvr	A	170	201	ADALKKRLAAYHAQTEPIVDFYKKTGIWAGVD	HHHHHHHHHHHHHHHHHHHHHHHHTT-EEEEE	aaaaaaaaaaaaaaaaaaaaaaaaavaxbxbx
1uke_*_142	1uke	-	142	173	IESIKKRFNTFNVQTKLVIDHYNKFDKVKIIP	HHHHHHHHHHHHHHHHHHHHHHHTTT-EEEEE	aaaaaaaaaaaaaaaaaaaaaaaaalabbbbx
2ak3_A_164	2ak3	A	164	195	PETVVKRLKAYEAQTEPVLEYYRKKGVLETFS	HHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEE	aaaaaaaaaaaaaaaaaaaaaaaaavaxbbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1uke_*_142	1uke	*	UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE	R - 148
1uke_*_142	1uke	*	UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE	T - 151

Bibliographic annotations

Loop	PDB	Chain	Annotation	Residue
2ak3_A_164	2ak3 RefK.DIEDERICHS,G.E.SCHULZ. THE THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN MITOCHONDRIAL MATRIX ADENYLATE KINASE AND ITS SUBSTRATE AMP AT 1.85 ANGSTROMS RESOLUTION J.MOL.BIOL v.217;541,1991	A	HIGHCONSERVATION	P - 180
2ak3_A_164	2ak3 RefK.DIEDERICHS,G.E.SCHULZ. THE THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN MITOCHONDRIAL MATRIX ADENYLATE KINASE AND ITS SUBSTRATE AMP AT 1.85 ANGSTROMS RESOLUTION J.MOL.BIOL v.217;541,1991	A	HIGHCONSERVATION	P - 180

Clusters included in this Subclass