ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 3.12.1

Subclass Accession number: 1207
Subclass: 3.12.1

Type: EH beta-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
GO : GO:0030151 (>75 %) GO:0046914 (>75 %)
SCOP : 52517 (>75 %) 52518 (>75 %) 52539 (>50 %) 52540 (>50 %) 53705 (>75 %) 53706 (>75 %) 53707 (>75 %)

Number of loops: 9

Average sequence ID (%) : 11.9 +/- 17.0
Average RMSD (Å) : 0.900 +/- 0.278

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 135-180

Consensus Sequence:	XXXXpXp
(φψ)-conformation:	bbpapaa

Pattern:	[fiktv]	[agiltv]	x	[acimtv]	[asv]	[EGPT]	[adqst]	x	[aders]	x	x	[AENPQST]	x	[erst]	[ikltv]
Conservation:	0.311	-0.901	-1.381	-0.255	1.303	1.030	0.208	-0.948	0.273	-0.321	-1.699	0.367	0.087	2.049	-0.123

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bg2_*_295	1bg2	-	299	313	VICCSPSSYNESETK	EEEE--BGGGHHHHH	bxbbxaxaaaaaaaa
1ctq_A_49	1ctq	A	55	69	ILDTAGQEEYSAMRD	EEEE---GGGHHHHH	bbxbxaxaaaaaaaa
1f9v_A_693	1f9v	A	697	711	FVNISPSSSHINETL	EEEE--SGGGHHHHH	bxxbxaxaaaaaaaa
1n6m_A_640	1n6m	A	644	658	FINVSPFQDCFQESV	EEEE--BGGGHHHHH	bxxbbapaaaaaaaa
1ozh_A_134	1ozh	A	134	148	YAIEVTAPDALAEVV	EEEE--SGGGHHHHH	bbbbxabaaaaaaaa
1ozh_A_511	1ozh	A	511	525	KGFAVESAEALEPTL	EEEE--SGGGHHHHH	xbbbxabaaaaaaaa
1pvd_A_135	1pvd	A	135	149	TTAMITDIATAPAEI	EEEE---TTTHHHHH	bbbbxabaaaaaaaa
1ry6_A_301	1ry6	A	305	319	IANISPTISCCEQTL	EEEE--BGGGHHHHH	xxxbxaxaaaaaaaa
3rab_A_69	3rab	A	75	89	IWDTAGQERYRTITT	EEEE--SGGGHHHHH	xxbxxapaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1bg2_*_295	1bg2	*	ADPADENOSINE-5'-DIPHOSPHATE	C - 301
1ctq_A_49	1ctq	A	MGMAGNESIUM ION	D - 57
1ctq_A_49	1ctq	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	D - 57
1ctq_A_49	1ctq	A	MGMAGNESIUM ION	T - 58
1ctq_A_49	1ctq	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	T - 58
1ctq_A_49	1ctq	A	MGMAGNESIUM ION	A - 59
1ctq_A_49	1ctq	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	A - 59
1ctq_A_49	1ctq	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	G - 60
1ctq_A_49	1ctq	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	Q - 61
1f9v_A_693	1f9v	A	ADPADENOSINE-5'-DIPHOSPHATE	K - 693
1f9v_A_693	1f9v	A	ADPADENOSINE-5'-DIPHOSPHATE	T - 694
1f9v_A_693	1f9v	A	ADPADENOSINE-5'-DIPHOSPHATE	L - 695
1f9v_A_693	1f9v	A	ADPADENOSINE-5'-DIPHOSPHATE	M - 696
1f9v_A_693	1f9v	A	ADPADENOSINE-5'-DIPHOSPHATE	N - 699
1n6m_A_640	1n6m	A	ADPADENOSINE-5'-DIPHOSPHATE	N - 646
3rab_A_69	3rab	A	MGMAGNESIUM ION	D - 77
3rab_A_69	3rab	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	D - 77
3rab_A_69	3rab	A	MGMAGNESIUM ION	T - 78
3rab_A_69	3rab	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	T - 78
3rab_A_69	3rab	A	MGMAGNESIUM ION	A - 79
3rab_A_69	3rab	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	A - 79
3rab_A_69	3rab	A	MGMAGNESIUM ION	G - 80
3rab_A_69	3rab	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	G - 80
3rab_A_69	3rab	A	GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	Q - 81

Clusters included in this Subclass

CLUSTER: EH.6.23

CLUSTER: EH.7.27

CLUSTER: EH.7.9