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Information on SUBCLASS 3.3.2
Subclass Accession number: 125
Subclass: 3.3.2
Type: HE alpha-beta
DB: ArchDB-KI
 Number of loops: 6

Average sequence ID (%) : 46.7 +/- 9.9
Average RMSD (Å) : 0.47 +/- 0.18

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 45-90
Consensus Sequence: ppGhPXI
(φψ)-conformation: aalppbb
Pattern: [AK]{GM}{IT}x[AI]x{FK}x[ACMV]{EN}{AEK}{AY}[G]{IV}[P]x[I]
Conservation:-0.020-0.546-0.575-0.3450.026-0.998-0.743-0.839-0.318-0.247-0.2870.0442.092-0.3312.586-0.6011.103
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a49_A_3051a49   A308324AQKMIIGRCNRAGKPVIHHHHHHHHHHHHT--EEaaaaaaaaaaaavbpbb
1ake_A_131ake   A1329KGTQAQFIMEKYGIPQIHHHHHHHHHHHH---EEaaaaaaaaaaaalbxxb
1ank_A_131ank   A1329KGTQAQFIMEKYGIPQIHHHHHHHHHHHH---EEaaaaaaaaaaaavxxbb
1c3q_A_711c3q   A7692AMIIAGKSANEHGVPVIHHHHHHHHHHHHT--EEaaaaaaaaaaaavxpbb
1zip_*_131zip   -1329KGTQAEKIVAAYGIPHIHHHHHHHHHHHH---EEaaaaaaaaaaaavbxxb
2eck_A_132eck   A1329KGTQAQFIMEKYGIPQIHHHHHHHHHHHH---EEaaaaaaaaaaaagpxxb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a49_A_3051a49   A     OXLOXALATE ION A - 326
1ake_A_131ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE K - 13
1ake_A_131ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 14
1ake_A_131ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE T - 15
1ake_A_131ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 16
1ake_A_131ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE S - 30
1ank_A_131ank   A     AMPADENOSINE MONOPHOSPHATE K - 13
1ank_A_131ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER K - 13
1ank_A_131ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER G - 14
1ank_A_131ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER T - 15
1ank_A_131ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Q - 16
1zip_*_131zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE K - 13
1zip_*_131zip   *     MNMANGANESE (II) ION K - 13
1zip_*_131zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 14
1zip_*_131zip   *     MNMANGANESE (II) ION G - 14
1zip_*_131zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE T - 15
1zip_*_131zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 16
1zip_*_131zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE S - 30
1zip_*_131zip   *     MNMANGANESE (II) ION S - 30
2eck_A_132eck   A     AMPADENOSINE MONOPHOSPHATE K - 13
2eck_A_132eck   A     ADPADENOSINE-5'-DIPHOSPHATE K - 13
2eck_A_132eck   A     ADPADENOSINE-5'-DIPHOSPHATE G - 14
2eck_A_132eck   A     ADPADENOSINE-5'-DIPHOSPHATE T - 15
2eck_A_132eck   A     ADPADENOSINE-5'-DIPHOSPHATE Q - 16
2eck_A_132eck   A     ADPADENOSINE-5'-DIPHOSPHATE A - 17
Bibliographic annotations
LoopPDBChainAnnotationResidue
1ake_A_131ake   RefC.W.MUELLER,G.E.SCHULZ. STRUCTURE OF THE COMPLEX BETWEEN ADENYLATE KINASE FROM ESCHERICHIA COLI AND THE INHIBITOR AP=5=A REFINED AT 1.9 ANGSTROMS RESOLUTION: A MODEL FOR A CATALYTIC TRANSITION STATE  J.MOL.BIOL. v.224;159,1992AP-LOOPK - 13
1c3q_A_711c3q   RefN.CAMPOBASSO,I.I.MATHEWS,T.P.BEGLEY,S.E.EALICK. CRYSTAL STRUCTURE OF 4-METHYL-5-BETA-HYDROXYETHYLTHIAZOLE KINASE FROM BACILLUS SUBTILIS AT 1.5 A RESOLUTION  BIOCHEMISTRY v.39;7868,2000AMg ION BINDING RESIDUED - 94

Clusters included in this Subclass
CLUSTER: HE.2.10
CLUSTER: HE.2.23
CLUSTER: HE.4.9