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Information on SUBCLASS 4.12.1
Subclass Accession number: 1265
Subclass: 4.12.1 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1 (>75 %)  1.1 (>50 %)  1.1.1 (>50 %)  1.1.1.37
GO : GO:0004457 (>75 %)  GO:0004459 (>75 %)  GO:0004812 (>75 %)  GO:0008452 (>75 %)  GO:0016614 (>75 %)  GO:0016615 (>50 %)  GO:0016616 (>75 %)  GO:0016874 (>75 %)  GO:0016875 (>75 %)  GO:0016876 (>75 %)  GO:0016886 (>75 %)  GO:0030060 (>50 %)  GO:0030145 (>50 %)  GO:0046914 (>50 %)  
SCOP : 55680 (>75 %)  55681 (>75 %)  55682 (>75 %)  56326 (>75 %)  56327 (>75 %)  56328 (>75 %)  
 Number of loops: 12

Average sequence ID (%) : 16.3 +/- 18.8
Average RMSD (Å) : 0.967 +/- 0.352

Consensus geometry
d (Å): 15 delta (°): 0-45 theta (°): 90-135 rho (°): 0-45
Consensus Sequence: XXXXXpXp
(φψ)-conformation: bbppapaa
Pattern: [grs][afgilv]x[epr]x[hnstw][DEHNRS]x[adegknr]xxx[aekqrt]x
Conservation:2.171-1.018-0.7591.2240.079-0.1771.411-0.774-0.156-0.5030.099-0.8540.421-1.165
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1b5t_A_2071b5t   A210223GILPVSNFKQAKKFEE---S-HHHHHHHxbbwbabaaaaaaa
1b8a_A_3601b8a   A365378GGQREHRHDILVEQEEEB---HHHHHHHbexxxaxaaaaaaa
1bgx_T_3311bgx   T331344RVHRAPEPYKALRDEEE--S-HHHHHHHbxbxbabaaaaaaa
1c0a_A_4811c0a   A486499GSVRIHNGDMQQTVEEEB---HHHHHHHbbxxxabaaaaaaa
1e1o_A_4201e1o   A425438GFSELNDAEDQAEREEEB---HHHHHHHbbxxxaxaaaaaaa
1eov_A_4771eov   A482495GAQRIHDHALLQEREEEB---HHHHHHHbbxxxaxaaaaaaa
1kqf_A_4421kqf   A442455VNALRGHSNIQGLTEEE---BTTHHHHHbxxxxapaaaaaaa
1l0w_A_4751l0w   A480493GSIRIHDPRLQARVEEEB---HHHHHHHbbxxxaxaaaaaaa
1n9w_A_3441n9w   A349362GGQRIHRYEELLESEEEB---HHHHHHHbexbxaxaaaaaaa
1nnh_A_2141nnh   A219232GGEREWEYEKIVAKEEEB---HHHHHHHbbxbxaxaaaaaaa
1r0p_A_11051r0p   A11111124SLNRITDIGEVSQFEE-----HHHHHHHxxppbabaaaaaaa
1v93_A_2041v93   A207220GIMPVTSYRQLRRFEE-----HHHHHHHxbbxxabaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1b8a_A_3601b8a   A     MNMANGANESE (II) ION E - 361
1b8a_A_3601b8a   A     ATPADENOSINE-5'-TRIPHOSPHATE E - 361
1b8a_A_3601b8a   A     ATPADENOSINE-5'-TRIPHOSPHATE I - 362
1b8a_A_3601b8a   A     MNMANGANESE (II) ION S - 363
1b8a_A_3601b8a   A     ATPADENOSINE-5'-TRIPHOSPHATE S - 363
1b8a_A_3601b8a   A     MNMANGANESE (II) ION S - 364
1b8a_A_3601b8a   A     ATPADENOSINE-5'-TRIPHOSPHATE S - 364
1c0a_A_4811c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE E - 482
1c0a_A_4811c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE V - 483
1c0a_A_4811c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE G - 484
1c0a_A_4811c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE G - 485
1c0a_A_4811c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE G - 486
1c0a_A_4811c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE S - 487
1c0a_A_4811c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE R - 489
1e1o_A_4201e1o   A     LYSLYSINE E - 421
1e1o_A_4201e1o   A     GOLGLYCEROL E - 421
1e1o_A_4201e1o   A     LYSLYSINE N - 424
1e1o_A_4201e1o   A     GOLGLYCEROL N - 424
1e1o_A_4201e1o   A     LYSLYSINE G - 425
1e1o_A_4201e1o   A     LYSLYSINE F - 426
1e1o_A_4201e1o   A     GOLGLYCEROL F - 426
1e1o_A_4201e1o   A     LYSLYSINE E - 428
1e1o_A_4201e1o   A     GOLGLYCEROL Q - 442
1e1o_A_4201e1o   A     GOLGLYCEROL K - 446
1kqf_A_4421kqf   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE L - 445
1kqf_A_4421kqf   A     CSESELENOCYSTEINE R - 446
1kqf_A_4421kqf   A     6MOMOLYBDENUM(VI) ION R - 446
1kqf_A_4421kqf   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE R - 446
1kqf_A_4421kqf   A     CSESELENOCYSTEINE G - 447
1kqf_A_4421kqf   A     6MOMOLYBDENUM(VI) ION G - 447
1kqf_A_4421kqf   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE G - 447
1kqf_A_4421kqf   A     CSESELENOCYSTEINE H - 448
1kqf_A_4421kqf   A     6MOMOLYBDENUM(VI) ION H - 448
1kqf_A_4421kqf   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE H - 448
1kqf_A_4421kqf   A     CSESELENOCYSTEINE I - 451
1kqf_A_4421kqf   A     6MOMOLYBDENUM(VI) ION I - 451
1kqf_A_4421kqf   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE I - 451
1r0p_A_11051r0p   A     KSAK-252A A - 1108
1r0p_A_11051r0p   A     KSAK-252A K - 1110

Clusters included in this Subclass
CLUSTER: EH.4.60
CLUSTER: EH.5.148
CLUSTER: EH.5.159
CLUSTER: EH.5.90